SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f3y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		4 / 6 ILE A1093
TRP A1110
TYR A1141
VAL A1076
 None
 1.05A 1db1A-5f3yA:
undetectable		 1db1A-5f3yA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_A_SALA3005_1
(XANTHINE
DEHYDROGENASE)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		5 / 9 LEU A1408
ARG A1389
VAL A1471
LEU A1436
ALA A1466
 None
 1.47A 1fo4A-5f3yA:
2.5		 1fo4A-5f3yA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		4 / 4 ALA A1009
VAL A1013
ALA A1010
HIS A1007
 None
 1.22A 1q23F-5f3yA:
undetectable		 1q23F-5f3yA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		4 / 4 ALA A1009
VAL A1013
ALA A1010
HIS A1007
 None
 1.20A 1q23K-5f3yA:
undetectable		 1q23K-5f3yA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_B_BEZB1503_0
(RAS-RELATED PROTEIN
RAB-9A)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		4 / 6 VAL A1352
GLU A1308
LEU A1310
ARG A1312
 None
 1.12A 1s8fB-5f3yA:
undetectable		 1s8fB-5f3yA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BLA_A_CP6A302_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5f3y ANKYRIN REPEAT AND
SAM
DOMAIN-CONTAINING
PROTEIN 4B
(Mus
musculus) 		5 / 11 PHE B 275
ASN B 266
SER B 263
ILE B 264
ILE B 273
 None
 1.22A 2blaA-5f3yB:
undetectable		 2blaA-5f3yB:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		4 / 6 ILE A1544
MET A1434
THR A1452
LEU A1453
 None
 0.96A 2einN-5f3yA:
2.8
2einW-5f3yA:
undetectable		 2einN-5f3yA:
20.92
2einW-5f3yA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		4 / 5 LEU A1436
LEU A1408
ILE A1410
ALA A1466
 None
 0.76A 2i2zA-5f3yA:
undetectable		 2i2zA-5f3yA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_A_SC2A1290_1
(FICOLIN-2)		 5f3y ANKYRIN REPEAT AND
SAM
DOMAIN-CONTAINING
PROTEIN 4B
UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		4 / 5 SER A1295
LEU B 270
GLY B 269
ARG A1265
 None
 1.16A 2j2pA-5f3yA:
undetectable
2j2pB-5f3yA:
undetectable		 2j2pA-5f3yA:
18.00
2j2pB-5f3yA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA803_0
(FERROCHELATASE)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		4 / 5 LEU A1115
LEU A1112
ILE A1111
ARG A1108
 None
 0.85A 2qd4A-5f3yA:
undetectable		 2qd4A-5f3yA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		5 / 12 LEU A1478
VAL A1547
SER A1232
SER A1218
ASN A1214
 None
 1.42A 2y00A-5f3yA:
undetectable		 2y00A-5f3yA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		4 / 8 ARG A1151
ASP A1239
GLU A1245
GLU A1166
 None
 1.20A 3dh0A-5f3yA:
undetectable		 3dh0A-5f3yA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWS_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		5 / 12 ALA A 977
ALA A 985
LEU A 998
ILE A 990
PHE A1133
 None
 1.05A 3gwsX-5f3yA:
undetectable		 3gwsX-5f3yA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_H_TRUH800_1
(GLUTAMATE RECEPTOR 2)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		3 / 3 ILE A1262
SER A1198
SER A1218
 None
 0.55A 3iltH-5f3yA:
undetectable		 3iltH-5f3yA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_C_P77C203_1
(PROTEIN S100-A4)		 5f3y ANKYRIN REPEAT AND
SAM
DOMAIN-CONTAINING
PROTEIN 4B
UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		5 / 10 SER A1198
SER A1229
ILE B 273
GLU A1267
LEU A1390
 None
 1.45A 3m0wC-5f3yA:
undetectable
3m0wD-5f3yA:
undetectable
3m0wE-5f3yA:
undetectable
3m0wF-5f3yA:
1.3		 3m0wC-5f3yA:
11.55
3m0wD-5f3yA:
11.55
3m0wE-5f3yA:
11.55
3m0wF-5f3yA:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_C_ACHC323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		4 / 8 PHE A1417
GLU A1455
TYR A1457
LEU A1450
 None
 0.94A 3rqwC-5f3yA:
undetectable
3rqwD-5f3yA:
undetectable		 3rqwC-5f3yA:
19.65
3rqwD-5f3yA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		4 / 8 PHE A1417
GLU A1455
TYR A1457
LEU A1450
 None
 0.95A 3rqwI-5f3yA:
undetectable
3rqwJ-5f3yA:
undetectable		 3rqwI-5f3yA:
19.65
3rqwJ-5f3yA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_J_ACHJ323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		4 / 8 GLU A1455
TYR A1457
LEU A1450
PHE A1417
 None
 0.98A 3rqwF-5f3yA:
undetectable
3rqwJ-5f3yA:
undetectable		 3rqwF-5f3yA:
19.65
3rqwJ-5f3yA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_B_08JB2_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		4 / 7 VAL A1433
LEU A1450
LEU A1436
ILE A1410
 None
 0.87A 3u5kB-5f3yA:
undetectable		 3u5kB-5f3yA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		4 / 8 VAL A1433
LEU A1450
LEU A1436
ILE A1410
 None
 0.90A 3u5kD-5f3yA:
2.5		 3u5kD-5f3yA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		5 / 12 CYH A1334
TYR A1286
LEU A1331
VAL A1335
VAL A1352
 None
 1.19A 3u9fP-5f3yA:
undetectable
3u9fS-5f3yA:
undetectable		 3u9fP-5f3yA:
15.00
3u9fS-5f3yA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_A_SALA1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		5 / 9 LEU A1408
ARG A1389
VAL A1471
LEU A1436
ALA A1466
 None
 1.47A 3unaA-5f3yA:
2.4		 3unaA-5f3yA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		5 / 9 LEU A1408
ARG A1389
VAL A1471
LEU A1436
ALA A1466
 None
 1.47A 3unaB-5f3yA:
undetectable		 3unaB-5f3yA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_A_SALA1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		5 / 9 LEU A1408
ARG A1389
VAL A1471
LEU A1436
ALA A1466
 None
 1.49A 3uncA-5f3yA:
0.6		 3uncA-5f3yA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		4 / 6 ILE A1544
MET A1434
THR A1452
LEU A1453
 None
 0.94A 3wg7N-5f3yA:
1.6
3wg7W-5f3yA:
undetectable		 3wg7N-5f3yA:
20.92
3wg7W-5f3yA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		4 / 5 VAL A1433
LEU A1450
LEU A1436
ILE A1410
 None
 0.95A 4a9jB-5f3yA:
undetectable		 4a9jB-5f3yA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYS_A_ACTA402_0
(MCCC FAMILY PROTEIN)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		4 / 6 SER A1194
ASP A1193
ARG A1151
GLU A1200
 None
 1.01A 4eysA-5f3yA:
undetectable		 4eysA-5f3yA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		5 / 12 MET A1470
LEU A1473
GLY A1476
ILE A1410
PHE A1430
 None
 1.16A 4p6xA-5f3yA:
undetectable		 4p6xA-5f3yA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		5 / 12 MET A1470
LEU A1473
GLY A1477
ILE A1410
PHE A1430
 None
 1.11A 4p6xA-5f3yA:
undetectable		 4p6xA-5f3yA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA703_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 5f3y ANKYRIN REPEAT AND
SAM
DOMAIN-CONTAINING
PROTEIN 4B
UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		4 / 4 LEU B 270
PHE A1227
LEU A1386
GLU A1297
 None
 1.33A 4p7nA-5f3yB:
undetectable		 4p7nA-5f3yB:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		3 / 3 PRO A1122
VAL A1157
HIS A1236
 None
 0.83A 4pevC-5f3yA:
undetectable		 4pevC-5f3yA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_1
(GLUCOCORTICOID
RECEPTOR)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		5 / 12 MET A1470
LEU A1473
GLY A1476
ILE A1410
PHE A1430
 None
 1.15A 4udcA-5f3yA:
undetectable		 4udcA-5f3yA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_1
(GLUCOCORTICOID
RECEPTOR)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		5 / 12 MET A1470
LEU A1473
GLY A1477
ILE A1410
PHE A1430
 None
 1.23A 4udcA-5f3yA:
undetectable		 4udcA-5f3yA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		4 / 6 VAL A1072
LEU A1117
SER A1114
ILE A1134
 None
 1.00A 5jw1A-5f3yA:
1.4		 5jw1A-5f3yA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		4 / 6 ILE A1544
MET A1434
THR A1452
LEU A1453
 None
 0.95A 5z86N-5f3yA:
undetectable
5z86W-5f3yA:
undetectable		 5z86N-5f3yA:
20.92
5z86W-5f3yA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		4 / 6 ILE A1544
MET A1434
THR A1452
LEU A1453
 None
 0.96A 5zcoN-5f3yA:
1.5
5zcoW-5f3yA:
undetectable		 5zcoN-5f3yA:
20.92
5zcoW-5f3yA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_0
(SERUM ALBUMIN)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		5 / 12 LEU A1408
ILE A1467
PHE A1430
LEU A1557
LEU A1450
 None
 1.10A 6a7pA-5f3yA:
2.1		 6a7pA-5f3yA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA607_0
(ALPHA-AMYLASE)		 5f3y UNCONVENTIONAL
MYOSIN-VIIB
(Mus
musculus) 		4 / 4 ARG A1151
SER A1194
ASP A1193
ASN A1155
 None
 1.29A 6ag0A-5f3yA:
undetectable		 6ag0A-5f3yA:
8.90