SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f42'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_2
(HIV-II PROTEASE)		 5f42 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Francisella
tularensis) 		5 / 9 ALA A  60
ILE A  93
ILE A  86
ILE A  50
ILE A  62
 None
 0.83A 1hshB-5f42A:
undetectable		 1hshB-5f42A:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_1
(HIV-II PROTEASE)		 5f42 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Francisella
tularensis) 		5 / 12 ALA A  60
ILE A  93
ILE A  86
ILE A  50
ILE A  62
 None
 0.82A 1hshC-5f42A:
undetectable		 1hshC-5f42A:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_1
(HIV-1 PROTEASE)		 5f42 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Francisella
tularensis) 		5 / 12 ALA A  48
ILE A  32
GLY A  33
GLY A  51
ILE A  62
 None
 0.89A 1hxbA-5f42A:
undetectable		 1hxbA-5f42A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 5f42 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Francisella
tularensis) 		5 / 10 LEU A 136
ILE A  81
GLY A  82
GLY A 107
ILE A 118
 None
 0.94A 1sdtA-5f42A:
undetectable		 1sdtA-5f42A:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 5f42 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Francisella
tularensis) 		5 / 11 LEU A 136
ILE A  81
GLY A  82
GLY A 107
ILE A 118
 None
 0.93A 1sduA-5f42A:
undetectable		 1sduA-5f42A:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 5f42 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Francisella
tularensis) 		5 / 10 LEU A 136
ILE A  81
GLY A  82
GLY A 107
ILE A 118
 None
 0.91A 1sdvA-5f42A:
undetectable		 1sdvA-5f42A:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 5f42 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Francisella
tularensis) 		5 / 12 LEU A 130
ALA A 164
ALA A 170
GLY A 135
ILE A 128
 None
 1.04A 3c6gA-5f42A:
undetectable		 3c6gA-5f42A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5f42 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Francisella
tularensis) 		5 / 10 ILE A 194
ILE A 212
VAL A 242
LYS A 241
LEU A 219
 None
 1.13A 3em0A-5f42A:
undetectable		 3em0A-5f42A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_1
(PROTEASE)		 5f42 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Francisella
tularensis) 		5 / 9 ALA A  60
ILE A  93
ILE A  86
ILE A  50
ILE A  62
 None
 0.86A 3s43A-5f42A:
undetectable		 3s43A-5f42A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_1
(PROTEASE)		 5f42 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Francisella
tularensis) 		5 / 9 ALA A  60
ILE A  93
ILE A  86
ILE A  50
ILE A  62
 None
 0.97A 3s45A-5f42A:
undetectable		 3s45A-5f42A:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 5f42 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Francisella
tularensis) 		5 / 12 ILE A 166
ALA A 164
LEU A 148
LEU A 136
ILE A 124
 None
 0.89A 3uvvA-5f42A:
undetectable		 3uvvA-5f42A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_1
(PROTEASE)		 5f42 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Francisella
tularensis) 		5 / 12 ALA A  60
ILE A  93
ILE A  86
ILE A  50
ILE A  62
 None
 0.84A 5e5jA-5f42A:
undetectable		 5e5jA-5f42A:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 5f42 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Francisella
tularensis) 		4 / 8 VAL A  42
ILE A  26
ALA A  18
THR A  36
 None
 0.75A 5og9A-5f42A:
undetectable		 5og9A-5f42A:
21.93