SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f4y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_1
(ESTROGEN RECEPTOR)		 5f4y PROTEIN SHROOM2
(Homo
sapiens) 		4 / 6 ALA A1572
ASP A1573
GLU A1575
ARG A1556
 None
 1.22A 2ouzA-5f4yA:
4.2		 2ouzA-5f4yA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)		 5f4y PROTEIN SHROOM2
(Homo
sapiens) 		4 / 4 LEU A1447
GLY A1598
LEU A1602
GLU A1599
 None
 0.88A 3tgvB-5f4yA:
undetectable		 3tgvB-5f4yA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZPH_A_PRLA501_0
(ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
ENDOTHELIAL PAS
DOMAIN-CONTAINING
PROTEIN 1)		 5f4y PROTEIN SHROOM2
(Homo
sapiens) 		4 / 7 VAL A1461
GLN A1588
LEU A1457
GLU A1455
 None
 1.06A 4zphA-5f4yA:
undetectable
4zphB-5f4yA:
undetectable		 4zphA-5f4yA:
19.25
4zphB-5f4yA:
20.29