SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f5o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5f5o NUCLEOPROTEIN
(Marburg
marburgvirus) 		4 / 7 ILE A 191
PHE A  72
ARG A  82
ALA A  78
 None
 1.11A 1oniG-5f5oA:
undetectable
1oniI-5f5oA:
undetectable		 1oniG-5f5oA:
18.09
1oniI-5f5oA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZQ_A_PCFA954_0
(CATECHOL
1,2-DIOXYGENASE)		 5f5o NUCLEOPROTEIN
(Marburg
marburgvirus) 		5 / 9 GLU A 333
HIS A 330
ALA A 329
LEU A 325
LEU A 313
 None
 1.33A 2azqA-5f5oA:
undetectable		 2azqA-5f5oA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2003_1
(SERUM ALBUMIN)		 5f5o NUCLEOPROTEIN
(Marburg
marburgvirus) 		5 / 10 LEU A  59
PHE A 132
LEU A  52
ILE A 185
ALA A  41
 None
 1.10A 2bxeB-5f5oA:
undetectable		 2bxeB-5f5oA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_C_SC2C1289_1
(FICOLIN-2)		 5f5o NUCLEOPROTEIN
(Marburg
marburgvirus) 		4 / 6 ASP A 208
SER A 134
LEU A 131
GLY A 130
 None
 0.96A 2j2pA-5f5oA:
undetectable
2j2pC-5f5oA:
undetectable		 2j2pA-5f5oA:
20.61
2j2pC-5f5oA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 5f5o NUCLEOPROTEIN
(Marburg
marburgvirus) 		4 / 6 ASP A 208
SER A 134
LEU A 131
GLY A 130
 None
 0.97A 2j2pD-5f5oA:
undetectable
2j2pF-5f5oA:
undetectable		 2j2pD-5f5oA:
20.61
2j2pF-5f5oA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 5f5o NUCLEOPROTEIN
(Marburg
marburgvirus) 		4 / 8 ASP A 211
ILE A 214
HIS A  63
ASP A 208
 None
 1.02A 2xadC-5f5oA:
undetectable		 2xadC-5f5oA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5f5o NUCLEOPROTEIN
(Marburg
marburgvirus) 		5 / 12 GLY A  55
LEU A 133
LEU A 196
VAL A 195
ILE A 191
 None
 1.02A 3adsB-5f5oA:
undetectable		 3adsB-5f5oA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)		 5f5o NUCLEOPROTEIN
(Marburg
marburgvirus) 		3 / 3 GLU A  62
VAL A  32
CYH A  35
 None
 0.81A 3fbxA-5f5oA:
undetectable		 3fbxA-5f5oA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 5f5o NUCLEOPROTEIN
(Marburg
marburgvirus) 		5 / 12 LEU A  51
GLY A  49
TYR A 109
ILE A 103
ALA A  41
 None
 1.01A 3gwvA-5f5oA:
undetectable		 3gwvA-5f5oA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWW_A_SFXA801_1
(TRANSPORTER)		 5f5o NUCLEOPROTEIN
(Marburg
marburgvirus) 		5 / 12 LEU A  51
GLY A  49
TYR A 109
ILE A 103
ALA A  41
 None
 0.95A 3gwwA-5f5oA:
undetectable		 3gwwA-5f5oA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 5f5o NUCLEOPROTEIN
(Marburg
marburgvirus) 		5 / 12 CYH A 136
LEU A 133
LEU A  56
ILE A 182
ILE A  42
 None
 0.93A 3ut5B-5f5oA:
undetectable		 3ut5B-5f5oA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5f5o NUCLEOPROTEIN
(Marburg
marburgvirus) 		5 / 11 LEU A 140
SER A 217
ILE A  42
ILE A 182
VAL A 158
 None
 1.07A 3w67A-5f5oA:
0.8		 3w67A-5f5oA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5f5o NUCLEOPROTEIN
(Marburg
marburgvirus) 		5 / 12 ILE A 129
LEU A 140
SER A 217
ILE A 182
VAL A 158
 None
 1.14A 3w67C-5f5oA:
undetectable		 3w67C-5f5oA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1477_0
(MJ0495-LIKE PROTEIN)		 5f5o NUCLEOPROTEIN
(Marburg
marburgvirus) 		4 / 6 GLY A  54
ARG A  82
ILE A 191
LEU A  59
 None
 0.83A 4ac9C-5f5oA:
undetectable		 4ac9C-5f5oA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1477_0
(MJ0495-LIKE PROTEIN)		 5f5o NUCLEOPROTEIN
(Marburg
marburgvirus) 		4 / 6 THR A  58
GLY A  54
ARG A  82
ILE A 191
 None
 1.24A 4ac9C-5f5oA:
undetectable		 4ac9C-5f5oA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5f5o NUCLEOPROTEIN
(Marburg
marburgvirus) 		4 / 6 GLY A  54
ARG A  82
ILE A 191
LEU A  59
 None
 0.85A 4acaC-5f5oA:
undetectable		 4acaC-5f5oA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5f5o NUCLEOPROTEIN
(Marburg
marburgvirus) 		4 / 6 THR A  58
GLY A  54
ARG A  82
ILE A 191
 None
 1.26A 4acaC-5f5oA:
undetectable		 4acaC-5f5oA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5f5o NUCLEOPROTEIN
(Marburg
marburgvirus) 		4 / 6 GLY A  54
ARG A  82
ILE A 191
LEU A  59
 None
 0.83A 4acbC-5f5oA:
undetectable		 4acbC-5f5oA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 5f5o NUCLEOPROTEIN
(Marburg
marburgvirus) 		4 / 8 SER A 217
GLN A 220
VAL A 160
THR A 159
 None
 0.90A 4lnwA-5f5oA:
undetectable		 4lnwA-5f5oA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 5f5o NUCLEOPROTEIN
(Marburg
marburgvirus) 		4 / 6 SER A 217
GLN A 220
VAL A 160
THR A 159
 None
 0.72A 4lnxA-5f5oA:
undetectable		 4lnxA-5f5oA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5f5o NUCLEOPROTEIN
(Marburg
marburgvirus) 		5 / 12 GLY A  45
ASN A  43
ASP A  40
ALA A 115
PHE A  99
 None
 1.11A 4u8vB-5f5oA:
undetectable		 4u8vB-5f5oA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5f5o NUCLEOPROTEIN
(Marburg
marburgvirus) 		5 / 12 GLY A  45
ASN A  43
ASP A  40
ALA A 115
PHE A  99
 None
 1.13A 4u95B-5f5oA:
undetectable		 4u95B-5f5oA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_C_ANWC601_0
(RHODOPSIN KINASE)		 5f5o NUCLEOPROTEIN
(Marburg
marburgvirus) 		4 / 6 ARG A 280
LEU A 226
ALA A 276
LEU A 266
 None
 0.73A 4wboC-5f5oA:
undetectable		 4wboC-5f5oA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		 5f5o NUCLEOPROTEIN
(Marburg
marburgvirus) 		4 / 6 LEU A 119
LEU A 112
ILE A  34
PHE A  99
 None
 1.27A 4y4dA-5f5oA:
undetectable		 4y4dA-5f5oA:
20.82