SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f5p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 5f5p PROTEIN SHROOM2
RHO-ASSOCIATED
PROTEIN KINASE 1
(Homo
sapiens;
Homo
sapiens) 		5 / 12 LEU A1501
ILE A1586
SER A1506
ALA C 848
PHE C 852
 None
None
None
None
CL  A1701 ( 4.5A)
 1.02A 2ejtA-5f5pA:
undetectable		 2ejtA-5f5pA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 5f5p PROTEIN SHROOM2
(Homo
sapiens) 		4 / 8 TYR A1575
GLU A1556
PHE A1491
VAL A1472
 None
 1.14A 2fl5E-5f5pA:
undetectable
2fl5F-5f5pA:
undetectable		 2fl5E-5f5pA:
23.11
2fl5F-5f5pA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 5f5p RHO-ASSOCIATED
PROTEIN KINASE 1
(Homo
sapiens) 		3 / 3 TYR C 851
LEU C 863
LYS C 861
 None
 0.78A 3sueD-5f5pC:
undetectable		 3sueD-5f5pC:
17.50