SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f5r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5f5r HEAT SHOCK PROTEIN
75 KDA,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 THR A  94
GLY A 173
GLY A 235
LEU A  98
SER A 233
 None
 0.97A 1jhoA-5f5rA:
undetectable		 1jhoA-5f5rA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5f5r HEAT SHOCK PROTEIN
75 KDA,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 THR A  94
GLY A 173
GLY A 235
LEU A  98
SER A 233
 None
 1.00A 1jhrA-5f5rA:
undetectable		 1jhrA-5f5rA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5f5r HEAT SHOCK PROTEIN
75 KDA,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 THR A  94
GLY A 173
GLY A 235
LEU A  98
SER A 233
 None
 1.00A 1jhyA-5f5rA:
undetectable		 1jhyA-5f5rA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5f5r HEAT SHOCK PROTEIN
75 KDA,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 THR A  94
GLY A 173
GLY A 235
LEU A  98
SER A 233
 None
 1.01A 1l4nA-5f5rA:
undetectable		 1l4nA-5f5rA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5f5r HEAT SHOCK PROTEIN
75 KDA,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 THR A  94
GLY A 173
GLY A 235
LEU A  98
SER A 233
 None
 1.01A 1l5kA-5f5rA:
undetectable		 1l5kA-5f5rA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5f5r HEAT SHOCK PROTEIN
75 KDA,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 THR A  94
GLY A 173
GLY A 235
LEU A  98
SER A 233
 None
 1.00A 1l5lA-5f5rA:
undetectable		 1l5lA-5f5rA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5f5r HEAT SHOCK PROTEIN
75 KDA,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 THR A  94
GLY A 173
GLY A 235
LEU A  98
SER A 233
 None
 1.01A 1l5mA-5f5rA:
undetectable		 1l5mA-5f5rA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 5f5r HEAT SHOCK PROTEIN
75 KDA,
MITOCHONDRIAL
(Homo
sapiens) 		3 / 3 TRP A 231
THR A  94
TYR A 206
 None
 1.26A 2a3aA-5f5rA:
undetectable		 2a3aA-5f5rA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 5f5r HEAT SHOCK PROTEIN
75 KDA,
MITOCHONDRIAL
(Homo
sapiens) 		3 / 3 TRP A 231
THR A  94
TYR A 206
 None
 1.29A 2a3bA-5f5rA:
undetectable		 2a3bA-5f5rA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA502_1
(CYTOCHROME P450 2C8)		 5f5r HEAT SHOCK PROTEIN
75 KDA,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 ILE A 253
ILE A 255
LEU A 116
VAL A 211
ILE A 143
 None
 0.96A 2nnhA-5f5rA:
undetectable		 2nnhA-5f5rA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3A_A_TOPA1190_1
(DIHYDROFOLATE
REDUCTASE)		 5f5r HEAT SHOCK PROTEIN
75 KDA,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 11 ILE A  75
GLU A  79
THR A 153
ILE A 255
THR A  78
 None
 1.23A 2w3aA-5f5rA:
undetectable		 2w3aA-5f5rA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGQ_A_PCFA1275_0
(WNT INHIBITORY
FACTOR 1)		 5f5r HEAT SHOCK PROTEIN
75 KDA,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 LEU A 116
LEU A 168
ILE A 253
PHE A 205
PHE A  90
 None
 0.86A 2ygqA-5f5rA:
undetectable		 2ygqA-5f5rA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_B_SALB104_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 5f5r HEAT SHOCK PROTEIN
75 KDA,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 VAL A 211
ARG A 269
VAL A 270
ILE A 113
ILE A 154
 None
 0.85A 3hgxB-5f5rA:
undetectable		 3hgxB-5f5rA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB201_1
(PROTEIN S100-A4)		 5f5r HEAT SHOCK PROTEIN
75 KDA,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 8 GLY A 162
ILE A 241
PHE A 209
PHE A 205
 ANP  A 300 ( 4.5A)
None
None
None
 0.87A 3ko0B-5f5rA:
undetectable
3ko0J-5f5rA:
undetectable		 3ko0B-5f5rA:
18.22
3ko0J-5f5rA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK201_1
(PROTEIN S100-A4)		 5f5r HEAT SHOCK PROTEIN
75 KDA,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 8 GLY A 162
ILE A 241
PHE A 209
PHE A 205
 ANP  A 300 ( 4.5A)
None
None
None
 0.88A 3ko0K-5f5rA:
undetectable
3ko0S-5f5rA:
undetectable		 3ko0K-5f5rA:
18.22
3ko0S-5f5rA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_A_SALA301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 5f5r HEAT SHOCK PROTEIN
75 KDA,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 8 VAL A 211
ARG A 269
VAL A 270
ILE A 154
 None
 0.77A 3remA-5f5rA:
undetectable		 3remA-5f5rA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_B_SALB301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 5f5r HEAT SHOCK PROTEIN
75 KDA,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 8 VAL A 211
ARG A 269
VAL A 270
ILE A 154
 None
 0.78A 3remB-5f5rA:
undetectable		 3remB-5f5rA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_F_BEZF501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 5f5r HEAT SHOCK PROTEIN
75 KDA,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 8 ALA A 208
SER A 207
LEU A 116
TYR A 206
 None
 1.22A 4ijiF-5f5rA:
undetectable		 4ijiF-5f5rA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5f5r HEAT SHOCK PROTEIN
75 KDA,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 THR A  94
GLY A 173
GLY A 235
LEU A  98
SER A 233
 None
 0.95A 4kqiA-5f5rA:
undetectable		 4kqiA-5f5rA:
21.07