SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f5y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2E5D_A_NCAA1501_0 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	5f5y	PROTEIN CYCLE (Drosophila melanogaster)	4 / 7	PHE A 311 ARG A 327 ALA A 407 ASP A 325	None None EDO A 501 (-3.3A) None	1.08A	2e5dA-5f5yA: undetectable 2e5dB-5f5yA: undetectable	2e5dA-5f5yA: 12.45 2e5dB-5f5yA: 12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2E5D_B_NCAB1502_0 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	5f5y	PROTEIN CYCLE (Drosophila melanogaster)	4 / 7	ASP A 325 PHE A 311 ARG A 327 ALA A 407	None None None EDO A 501 (-3.3A)	1.07A	2e5dA-5f5yA: undetectable 2e5dB-5f5yA: undetectable	2e5dA-5f5yA: 12.45 2e5dB-5f5yA: 12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VMY_B_GLYB502_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	5f5y	PROTEIN CYCLE (Drosophila melanogaster)	4 / 8	TYR A 375 SER A 389 HIS A 315 SER A 313	EDO A 501 (-4.3A) EDO A 501 (-3.4A) EDO A 501 (-4.0A) EDO A 501 (-3.7A)	1.32A	2vmyA-5f5yA: undetectable 2vmyB-5f5yA: undetectable	2vmyA-5f5yA: 13.72 2vmyB-5f5yA: 13.72

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2E5D_A_NCAA1501_0","NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE","5f5y","PROTEIN CYCLE","Drosophila melanogaster",4,"PHE A 311;ARG A 327;ALA A 407;ASP A 325","None;None;EDO A 501 (-3.3A);None","1.08A","2e5dA-5f5yA:undetectable;2e5dB-5f5yA:undetectable","2e5dA-5f5yA:12.45;2e5dB-5f5yA:12.45"],["2E5D_B_NCAB1502_0","NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE","5f5y","PROTEIN CYCLE","Drosophila melanogaster",4,"ASP A 325;PHE A 311;ARG A 327;ALA A 407","None;None;None;EDO A 501 (-3.3A)","1.07A","2e5dA-5f5yA:undetectable;2e5dB-5f5yA:undetectable","2e5dA-5f5yA:12.45;2e5dB-5f5yA:12.45"],["2VMY_B_GLYB502_0","SERINE HYDROXYMETHYLTRANSFERASE","5f5y","PROTEIN CYCLE","Drosophila melanogaster",4,"TYR A 375;SER A 389;HIS A 315;SER A 313","EDO A 501 (-4.3A);EDO A 501 (-3.4A);EDO A 501 (-4.0A);EDO A 501 (-3.7A)","1.32A","2vmyA-5f5yA:undetectable;2vmyB-5f5yA:undetectable","2vmyA-5f5yA:13.72;2vmyB-5f5yA:13.72"]]