SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f67'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN0_A_TDZA501_1
(CYTOCHROME P450 2C8)
5f67 INACTIVATION-NO-AFTE
R-POTENTIAL D
PROTEIN

(Drosophila
melanogaster)
5 / 12 LEU A 375
ASN A 401
VAL A 379
VAL A 407
GLU A 403
None
1.15A 2vn0A-5f67A:
undetectable
2vn0A-5f67A:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
5f67 INACTIVATION-NO-AFTE
R-POTENTIAL D
PROTEIN

(Drosophila
melanogaster)
3 / 3 GLY A 376
VAL A 367
MET A 442
None
0.61A 5ycpA-5f67A:
undetectable
5ycpA-5f67A:
22.94