SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f6j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_1
(MODIFICATION
METHYLASE RSRI)		 5f6j ENVELOPE
GLYCOPROTEIN GP120
OF HIV-1 CLADE C
(Human
immunodeficiency
virus
1) 		3 / 3 ASP G  78
HIS G 216
ASP G  57
 None
 0.70A 1nw5A-5f6jG:
undetectable		 1nw5A-5f6jG:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 5f6j ENVELOPE
GLYCOPROTEIN GP120
OF HIV-1 CLADE C
(Human
immunodeficiency
virus
1) 		4 / 8 PHE G 468
ILE G 359
GLY G 393
PHE G 361
 None
 0.66A 1rtsA-5f6jG:
undetectable		 1rtsA-5f6jG:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_0
(AMINOMETHYLTRANSFERA
SE)		 5f6j ENVELOPE
GLYCOPROTEIN GP120
OF HIV-1 CLADE C
(Human
immunodeficiency
virus
1) 		5 / 12 MET G 100
THR G 244
LEU G 226
ILE G 225
ARG G 480
 None
 1.34A 1wsvA-5f6jG:
undetectable		 1wsvA-5f6jG:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)		 5f6j ENVELOPE
GLYCOPROTEIN GP120
OF HIV-1 CLADE C
(Human
immunodeficiency
virus
1) 		5 / 12 ASN G 276
GLY G 235
MET G  95
PHE G  93
LYS G  97
 None
 1.50A 3r24A-5f6jG:
undetectable		 3r24A-5f6jG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 5f6j ENVELOPE
GLYCOPROTEIN GP120
OF HIV-1 CLADE C
(Human
immunodeficiency
virus
1) 		3 / 3 ARG G 379
PRO G 212
ASN G 262
 None
 0.86A 5jwaA-5f6jG:
undetectable
5jwaH-5f6jG:
undetectable		 5jwaA-5f6jG:
21.90
5jwaH-5f6jG:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 5f6j ENVELOPE
GLYCOPROTEIN GP120
OF HIV-1 CLADE C
(Human
immunodeficiency
virus
1) 		4 / 7 PHE G 468
ILE G 359
GLY G 393
PHE G 361
 None
 0.73A 5x5qC-5f6jG:
undetectable		 5x5qC-5f6jG:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 5f6j ENVELOPE
GLYCOPROTEIN GP120
OF HIV-1 CLADE C
(Human
immunodeficiency
virus
1) 		4 / 8 PHE G 468
ILE G 359
GLY G 393
PHE G 361
 None
 0.73A 5x5qD-5f6jG:
undetectable		 5x5qD-5f6jG:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 5f6j ENVELOPE
GLYCOPROTEIN GP120
OF HIV-1 CLADE C
(Human
immunodeficiency
virus
1) 		4 / 8 PHE G 468
ILE G 359
GLY G 393
PHE G 361
 None
 0.70A 5x5qF-5f6jG:
undetectable		 5x5qF-5f6jG:
17.22