SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f6q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_1
(HYPOTHETICAL PROTEIN
RV2118C)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		3 / 3 GLU A 115
HIS A  66
ASP A 100
 ZN  A 201 ( 2.4A)
ZN  A 201 ( 3.2A)
None
 0.85A 1i9gA-5f6qA:
undetectable		 1i9gA-5f6qA:
19.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NKI_A_PPFA5001_1
(PROBABLE FOSFOMYCIN
RESISTANCE PROTEIN)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		5 / 9 TYR A  64
HIS A  66
TYR A 105
GLU A 115
ARG A 124
 SO4  A 202 (-4.5A)
ZN  A 201 ( 3.2A)
SO4  A 202 (-4.8A)
ZN  A 201 ( 2.4A)
SO4  A 202 (-3.2A)
 0.39A 1nkiA-5f6qA:
18.0
1nkiB-5f6qA:
17.7		 1nkiA-5f6qA:
33.33
1nkiB-5f6qA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NKI_B_PPFB5002_1
(PROBABLE FOSFOMYCIN
RESISTANCE PROTEIN)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		5 / 9 TYR A  64
HIS A  66
TYR A 105
GLU A 115
ARG A 124
 SO4  A 202 (-4.5A)
ZN  A 201 ( 3.2A)
SO4  A 202 (-4.8A)
ZN  A 201 ( 2.4A)
SO4  A 202 (-3.2A)
 0.40A 1nkiA-5f6qA:
18.0
1nkiB-5f6qA:
17.7		 1nkiA-5f6qA:
33.33
1nkiB-5f6qA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_A_URFA999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		4 / 5 ALA A  38
TYR A  22
ILE A  19
ASP A 108
 None
 1.09A 1upfA-5f6qA:
undetectable		 1upfA-5f6qA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_C_URFC999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		4 / 5 ALA A  38
TYR A  22
ILE A  19
ASP A 108
 None
 1.03A 1upfC-5f6qA:
undetectable		 1upfC-5f6qA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		4 / 6 LEU A  42
PHE A  69
LEU A  26
PHE A  21
 None
 1.02A 3wg7P-5f6qA:
undetectable
3wg7W-5f6qA:
undetectable		 3wg7P-5f6qA:
19.26
3wg7W-5f6qA:
20.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IR0_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		5 / 11 HIS A   7
CYH A   9
TRP A  46
ALA A  48
ASN A  50
 None
 0.26A 4ir0A-5f6qA:
21.9
4ir0B-5f6qA:
22.8		 4ir0A-5f6qA:
97.89
4ir0B-5f6qA:
97.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IR0_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		6 / 11 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 SO4  A 202 (-4.5A)
ZN  A 201 ( 3.2A)
SO4  A 202 (-3.9A)
SO4  A 202 (-4.8A)
ZN  A 201 ( 2.4A)
SO4  A 202 (-3.2A)
 0.22A 4ir0A-5f6qA:
21.9
4ir0B-5f6qA:
22.8		 4ir0A-5f6qA:
97.89
4ir0B-5f6qA:
97.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IR0_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		5 / 11 HIS A   7
CYH A   9
TRP A  46
ALA A  48
ASN A  50
 None
 0.22A 4ir0A-5f6qA:
21.9
4ir0B-5f6qA:
22.8		 4ir0A-5f6qA:
97.89
4ir0B-5f6qA:
97.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IR0_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		6 / 11 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 SO4  A 202 (-4.5A)
ZN  A 201 ( 3.2A)
SO4  A 202 (-3.9A)
SO4  A 202 (-4.8A)
ZN  A 201 ( 2.4A)
SO4  A 202 (-3.2A)
 0.23A 4ir0A-5f6qA:
21.9
4ir0B-5f6qA:
22.8		 4ir0A-5f6qA:
97.89
4ir0B-5f6qA:
97.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JD1_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		6 / 12 HIS A   7
CYH A   9
TYR A  39
TRP A  46
ALA A  48
ASN A  50
 None
 0.31A 4jd1A-5f6qA:
21.9
4jd1B-5f6qA:
21.8		 4jd1A-5f6qA:
97.89
4jd1B-5f6qA:
97.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JD1_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		6 / 12 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 SO4  A 202 (-4.5A)
ZN  A 201 ( 3.2A)
SO4  A 202 (-3.9A)
SO4  A 202 (-4.8A)
ZN  A 201 ( 2.4A)
SO4  A 202 (-3.2A)
 0.30A 4jd1A-5f6qA:
21.9
4jd1B-5f6qA:
21.8		 4jd1A-5f6qA:
97.89
4jd1B-5f6qA:
97.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JD1_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		6 / 12 HIS A   7
CYH A   9
TYR A  39
TRP A  46
ALA A  48
ASN A  50
 None
 0.22A 4jd1A-5f6qA:
21.9
4jd1B-5f6qA:
21.8		 4jd1A-5f6qA:
97.89
4jd1B-5f6qA:
97.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JD1_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		6 / 12 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 SO4  A 202 (-4.5A)
ZN  A 201 ( 3.2A)
SO4  A 202 (-3.9A)
SO4  A 202 (-4.8A)
ZN  A 201 ( 2.4A)
SO4  A 202 (-3.2A)
 0.19A 4jd1A-5f6qA:
21.9
4jd1B-5f6qA:
21.8		 4jd1A-5f6qA:
97.89
4jd1B-5f6qA:
97.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH3_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		6 / 12 HIS A   7
CYH A   9
TYR A  39
TRP A  46
ALA A  48
ASN A  50
 None
 0.13A 4jh3A-5f6qA:
22.6
4jh3B-5f6qA:
22.7		 4jh3A-5f6qA:
68.12
4jh3B-5f6qA:
68.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH3_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		6 / 12 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 SO4  A 202 (-4.5A)
ZN  A 201 ( 3.2A)
SO4  A 202 (-3.9A)
SO4  A 202 (-4.8A)
ZN  A 201 ( 2.4A)
SO4  A 202 (-3.2A)
 0.16A 4jh3A-5f6qA:
22.6
4jh3B-5f6qA:
22.7		 4jh3A-5f6qA:
68.12
4jh3B-5f6qA:
68.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH3_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		5 / 11 HIS A   7
CYH A   9
TRP A  46
ALA A  48
ASN A  50
 None
 0.15A 4jh3A-5f6qA:
22.6
4jh3B-5f6qA:
22.7		 4jh3A-5f6qA:
68.12
4jh3B-5f6qA:
68.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH3_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		6 / 11 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 SO4  A 202 (-4.5A)
ZN  A 201 ( 3.2A)
SO4  A 202 (-3.9A)
SO4  A 202 (-4.8A)
ZN  A 201 ( 2.4A)
SO4  A 202 (-3.2A)
 0.21A 4jh3A-5f6qA:
22.6
4jh3B-5f6qA:
22.7		 4jh3A-5f6qA:
68.12
4jh3B-5f6qA:
68.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH4_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		5 / 11 HIS A   7
CYH A   9
TRP A  46
ALA A  48
ASN A  50
 None
 0.17A 4jh4A-5f6qA:
22.6
4jh4B-5f6qA:
22.5		 4jh4A-5f6qA:
68.12
4jh4B-5f6qA:
68.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH4_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		6 / 11 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 SO4  A 202 (-4.5A)
ZN  A 201 ( 3.2A)
SO4  A 202 (-3.9A)
SO4  A 202 (-4.8A)
ZN  A 201 ( 2.4A)
SO4  A 202 (-3.2A)
 0.25A 4jh4A-5f6qA:
22.6
4jh4B-5f6qA:
22.5		 4jh4A-5f6qA:
68.12
4jh4B-5f6qA:
68.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH4_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		5 / 11 HIS A   7
CYH A   9
TRP A  46
ALA A  48
ASN A  50
 None
 0.17A 4jh4A-5f6qA:
22.6
4jh4B-5f6qA:
22.5		 4jh4A-5f6qA:
68.12
4jh4B-5f6qA:
68.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH4_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		6 / 11 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 SO4  A 202 (-4.5A)
ZN  A 201 ( 3.2A)
SO4  A 202 (-3.9A)
SO4  A 202 (-4.8A)
ZN  A 201 ( 2.4A)
SO4  A 202 (-3.2A)
 0.22A 4jh4A-5f6qA:
22.6
4jh4B-5f6qA:
22.5		 4jh4A-5f6qA:
68.12
4jh4B-5f6qA:
68.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH5_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		5 / 11 HIS A   7
CYH A   9
TRP A  46
ALA A  48
ASN A  50
 None
 0.19A 4jh5A-5f6qA:
22.7
4jh5B-5f6qA:
22.4		 4jh5A-5f6qA:
68.12
4jh5B-5f6qA:
68.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH5_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		6 / 11 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 SO4  A 202 (-4.5A)
ZN  A 201 ( 3.2A)
SO4  A 202 (-3.9A)
SO4  A 202 (-4.8A)
ZN  A 201 ( 2.4A)
SO4  A 202 (-3.2A)
 0.23A 4jh5A-5f6qA:
22.7
4jh5B-5f6qA:
22.4		 4jh5A-5f6qA:
68.12
4jh5B-5f6qA:
68.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH5_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		5 / 11 HIS A   7
CYH A   9
TRP A  46
ALA A  48
ASN A  50
 None
 0.20A 4jh5A-5f6qA:
22.7
4jh5B-5f6qA:
22.4		 4jh5A-5f6qA:
68.12
4jh5B-5f6qA:
68.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH5_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		6 / 11 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 SO4  A 202 (-4.5A)
ZN  A 201 ( 3.2A)
SO4  A 202 (-3.9A)
SO4  A 202 (-4.8A)
ZN  A 201 ( 2.4A)
SO4  A 202 (-3.2A)
 0.18A 4jh5A-5f6qA:
22.7
4jh5B-5f6qA:
22.4		 4jh5A-5f6qA:
68.12
4jh5B-5f6qA:
68.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH6_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		6 / 10 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 SO4  A 202 (-4.5A)
ZN  A 201 ( 3.2A)
SO4  A 202 (-3.9A)
SO4  A 202 (-4.8A)
ZN  A 201 ( 2.4A)
SO4  A 202 (-3.2A)
 0.22A 4jh6A-5f6qA:
22.6
4jh6B-5f6qA:
22.6		 4jh6A-5f6qA:
68.12
4jh6B-5f6qA:
68.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH6_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		6 / 10 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 SO4  A 202 (-4.5A)
ZN  A 201 ( 3.2A)
SO4  A 202 (-3.9A)
SO4  A 202 (-4.8A)
ZN  A 201 ( 2.4A)
SO4  A 202 (-3.2A)
 0.16A 4jh6A-5f6qA:
22.6
4jh6B-5f6qA:
22.6		 4jh6A-5f6qA:
68.12
4jh6B-5f6qA:
68.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH8_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		6 / 10 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 SO4  A 202 (-4.5A)
ZN  A 201 ( 3.2A)
SO4  A 202 (-3.9A)
SO4  A 202 (-4.8A)
ZN  A 201 ( 2.4A)
SO4  A 202 (-3.2A)
 0.17A 4jh8A-5f6qA:
22.5
4jh8B-5f6qA:
22.4		 4jh8A-5f6qA:
68.12
4jh8B-5f6qA:
68.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JH8_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		6 / 10 TYR A  64
HIS A  66
ARG A  94
TYR A 105
GLU A 115
ARG A 124
 SO4  A 202 (-4.5A)
ZN  A 201 ( 3.2A)
SO4  A 202 (-3.9A)
SO4  A 202 (-4.8A)
ZN  A 201 ( 2.4A)
SO4  A 202 (-3.2A)
 0.12A 4jh8A-5f6qA:
22.5
4jh8B-5f6qA:
22.4		 4jh8A-5f6qA:
68.12
4jh8B-5f6qA:
68.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_F_URFF301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		3 / 3 ARG A  94
HIS A 117
ARG A  96
 SO4  A 202 (-3.9A)
None
SO4  A 202 ( 4.9A)
 1.17A 5iaoF-5f6qA:
undetectable		 5iaoF-5f6qA:
19.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V3D_A_FCNA205_1
(FOSFOMYCIN
RESISTANCE PROTEIN)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		5 / 10 TYR A  64
HIS A  66
TYR A 105
GLU A 115
ARG A 124
 SO4  A 202 (-4.5A)
ZN  A 201 ( 3.2A)
SO4  A 202 (-4.8A)
ZN  A 201 ( 2.4A)
SO4  A 202 (-3.2A)
 0.39A 5v3dA-5f6qA:
17.6
5v3dB-5f6qA:
17.6		 5v3dA-5f6qA:
34.04
5v3dB-5f6qA:
34.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5f6q METALLOTHIOL
TRANSFERASE FOSB 2
(Bacillus
anthracis) 		3 / 3 ASN A  89
VAL A  12
HIS A 112
 None
 0.81A 6a5yD-5f6qA:
undetectable		 6a5yD-5f6qA:
18.31