SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f6v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)
5f6v SUMO-CONJUGATING
ENZYME UBC9

(Homo
sapiens)
4 / 7 ILE A 116
LEU A 120
PHE A  58
GLY A  56
None
1.05A 4hbfA-5f6vA:
undetectable
4hbfA-5f6vA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)
5f6v SUMO-CONJUGATING
ENZYME UBC9

(Homo
sapiens)
4 / 6 ASN A 140
GLU A 145
TYR A 144
GLU A 143
None
1.29A 4mi4A-5f6vA:
undetectable
4mi4A-5f6vA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)
5f6v SUMO-CONJUGATING
ENZYME UBC9

(Homo
sapiens)
4 / 7 ASN A 140
GLU A 145
TYR A 144
GLU A 143
None
1.31A 4mj8C-5f6vA:
undetectable
4mj8C-5f6vA:
18.08