SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f72'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)		 5f72 SINGLE CHAIN FV FROM
A FAB
(Homo
sapiens) 		6 / 12 TYR T 177
GLN T 230
PHE T 239
VAL T  37
ALA T  97
TRP T 111
 None
 0.74A 1h8sA-5f72T:
21.8		 1h8sA-5f72T:
32.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		 5f72 SINGLE CHAIN FV FROM
A FAB
(Homo
sapiens) 		3 / 3 PHE T 212
TYR T 233
LEU T 188
 None
 0.75A 3keeB-5f72T:
undetectable		 3keeB-5f72T:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 5f72 SINGLE CHAIN FV FROM
A FAB
(Homo
sapiens) 		3 / 3 LYS T 183
LYS T 180
PRO T 181
 None
 1.19A 4dv1L-5f72T:
undetectable		 4dv1L-5f72T:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 5f72 SINGLE CHAIN FV FROM
A FAB
(Homo
sapiens) 		6 / 12 GLY T  26
ASP T 109
VAL T 110
VAL T   5
ALA T  23
LEU T   4
 None
 1.45A 5kocA-5f72T:
undetectable		 5kocA-5f72T:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4E_D_EDPD402_1
(PROTON-GATED ION
CHANNEL)		 5f72 SINGLE CHAIN FV FROM
A FAB
(Homo
sapiens) 		4 / 8 THR T 215
SER T 204
THR T 213
SER T 206
 None
 1.01A 5l4eA-5f72T:
undetectable
5l4eB-5f72T:
undetectable
5l4eC-5f72T:
undetectable
5l4eD-5f72T:
undetectable
5l4eE-5f72T:
undetectable		 5l4eA-5f72T:
21.25
5l4eB-5f72T:
21.25
5l4eC-5f72T:
21.25
5l4eD-5f72T:
21.25
5l4eE-5f72T:
21.25