SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f7c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 VAL A 553
TRP A 520
TRP A 505
 None
 1.18A 1c4dA-5f7cA:
undetectable
1c4dB-5f7cA:
undetectable		 1c4dA-5f7cA:
3.94
1c4dB-5f7cA:
3.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_1
(FTSJ)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A  55
ASP A 177
ASP A  16
 None
 0.79A 1eizA-5f7cA:
undetectable		 1eizA-5f7cA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_1
(FTSJ)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A  55
ASP A 177
ASP A  16
 None
 0.78A 1ej0A-5f7cA:
undetectable		 1ej0A-5f7cA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A 210
TYR A 238
PHE A 212
 None
 0.67A 1eqbB-5f7cA:
undetectable		 1eqbB-5f7cA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A 210
TYR A 238
PHE A 212
 None
 0.67A 1eqbA-5f7cA:
undetectable		 1eqbA-5f7cA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A 210
TYR A 238
PHE A 212
 None
 0.68A 1eqbD-5f7cA:
undetectable		 1eqbD-5f7cA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A 210
TYR A 238
PHE A 212
 None
 0.69A 1eqbC-5f7cA:
undetectable		 1eqbC-5f7cA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_A_FOLA605_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A  28
LEU A 195
THR A  44
ILE A  71
LEU A 155
 None
 1.13A 1qzfA-5f7cA:
undetectable		 1qzfA-5f7cA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_B_FOLB609_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A  28
LEU A 195
THR A  44
ILE A  71
LEU A 155
 None
 1.13A 1qzfB-5f7cA:
undetectable		 1qzfB-5f7cA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_C_FOLC613_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A  28
LEU A 195
THR A  44
ILE A  71
LEU A 155
 None
 1.12A 1qzfC-5f7cA:
undetectable		 1qzfC-5f7cA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_D_FOLD617_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A  28
LEU A 195
THR A  44
ILE A  71
LEU A 155
 None
 1.13A 1qzfD-5f7cA:
undetectable		 1qzfD-5f7cA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_E_FOLE621_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A  28
LEU A 195
THR A  44
ILE A  71
LEU A 155
 None
 1.13A 1qzfE-5f7cA:
undetectable		 1qzfE-5f7cA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_2
(TRANSTHYRETIN)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 LEU A  69
THR A  79
LEU A  83
VAL A 285
 None
 0.90A 1sn5C-5f7cA:
undetectable		 1sn5C-5f7cA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ALA A 509
PHE A 212
ARG A 236
ASN A 226
 None
 1.27A 1t9wA-5f7cA:
2.4		 1t9wA-5f7cA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 LEU A  69
THR A  79
LEU A  83
VAL A 285
 None
 0.80A 1tyrB-5f7cA:
undetectable		 1tyrB-5f7cA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 TRP A 596
GLU A 338
TYR A 340
 None
 1.22A 2a3aA-5f7cA:
2.8		 2a3aA-5f7cA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 GLY A 207
PHE A 243
PRO A 242
TYR A 244
 None
 1.18A 2aouB-5f7cA:
undetectable		 2aouB-5f7cA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D0K_A_FOLA1161_0
(DIHYDROFOLATE
REDUCTASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ALA A  28
LEU A 195
ILE A  71
LEU A 155
PRO A 157
ILE A 153
 None
 1.42A 2d0kA-5f7cA:
undetectable		 2d0kA-5f7cA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_A_SAMA801_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 10 GLU A 210
GLY A 537
LEU A 535
HIS A 519
PHE A 546
 None
 1.47A 2h21A-5f7cA:
undetectable		 2h21A-5f7cA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_B_SAMB802_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 11 GLU A 210
GLY A 537
LEU A 535
HIS A 519
PHE A 546
 None
 1.48A 2h21B-5f7cA:
undetectable		 2h21B-5f7cA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 TYR A 675
ASP A 644
TRP A 648
TRP A 695
 None
 1.30A 2ha2A-5f7cA:
undetectable		 2ha2A-5f7cA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 TYR A 675
ASP A 644
TRP A 648
TRP A 695
 None
 1.24A 2ha2B-5f7cA:
undetectable		 2ha2B-5f7cA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 TYR A 516
TYR A 298
PHE A 253
GLY A 303
 None
 1.15A 2ha4A-5f7cA:
undetectable		 2ha4A-5f7cA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_C_TPFC2471_1
(CYTOCHROME P450 121)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ASN A 481
PHE A 546
ALA A 509
GLN A 514
 None
 1.13A 2ij7C-5f7cA:
undetectable		 2ij7C-5f7cA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A 182
GLN A  48
LEU A  69
LEU A 165
PHE A  13
 None
 1.41A 2oaxE-5f7cA:
undetectable		 2oaxE-5f7cA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A 182
GLN A  48
LEU A  69
LEU A 165
PHE A  13
 None
 1.41A 2oaxF-5f7cA:
undetectable		 2oaxF-5f7cA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_D_MTXD617_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A  28
LEU A 195
THR A  44
ILE A  71
LEU A 155
 None
 1.16A 2oipD-5f7cA:
undetectable		 2oipD-5f7cA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_E_MTXE621_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A  28
LEU A 195
THR A  44
ILE A  71
LEU A 155
 None
 1.09A 2oipE-5f7cA:
undetectable		 2oipE-5f7cA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A 144
PRO A 145
ARG A 175
 None
 0.37A 2qd4B-5f7cA:
undetectable		 2qd4B-5f7cA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A 144
PRO A 145
ARG A 175
 None
 0.54A 2qd5A-5f7cA:
undetectable		 2qd5A-5f7cA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		7 / 12 ASN A 233
ASP A 348
ASP A 460
ARG A 507
ASP A 523
PHE A 556
HIS A 588
 None
 1.12A 2qmjA-5f7cA:
31.0		 2qmjA-5f7cA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		7 / 12 ASP A 228
ASP A 348
ASP A 460
ARG A 507
ASP A 523
PHE A 556
HIS A 588
 None
 0.45A 2qmjA-5f7cA:
31.0		 2qmjA-5f7cA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_GLYA333_0
(CHOLOYLGLYCINE
HYDROLASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASN A 226
ASN A 240
ARG A 211
 None
 0.90A 2rlcA-5f7cA:
undetectable		 2rlcA-5f7cA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ASP A 228
ASP A 348
ASP A 460
ASP A 523
PHE A 556
HIS A 588
 None
 0.63A 2x2iA-5f7cA:
28.8		 2x2iA-5f7cA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 THR A 459
THR A 237
GLY A 462
ALA A 484
GLN A 488
 None
 1.22A 2x2iA-5f7cA:
28.8		 2x2iA-5f7cA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ASP A 228
ASP A 348
ASP A 460
ASP A 523
PHE A 556
HIS A 588
 None
 0.61A 2x2iB-5f7cA:
21.6		 2x2iB-5f7cA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 228
GLN A 230
ASP A 523
PHE A 556
HIS A 588
 None
 1.03A 2x2iB-5f7cA:
21.6		 2x2iB-5f7cA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ASP A 228
ASP A 348
ASP A 460
ASP A 523
PHE A 556
HIS A 588
 None
 0.54A 2x2iC-5f7cA:
28.6		 2x2iC-5f7cA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 228
GLN A 230
ASP A 523
PHE A 556
HIS A 588
 None
 1.04A 2x2iC-5f7cA:
28.6		 2x2iC-5f7cA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 THR A 459
THR A 237
GLY A 462
ALA A 484
GLN A 488
 None
 1.24A 2x2iC-5f7cA:
28.6		 2x2iC-5f7cA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_D_QPSD1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ASP A 228
ASP A 348
ASP A 460
ASP A 523
PHE A 556
HIS A 588
 None
 0.55A 2x2iD-5f7cA:
26.0		 2x2iD-5f7cA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BSZ_E_RTLE177_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A  25
ALA A  28
ALA A 182
LEU A  12
GLN A 148
 None
 1.30A 3bszE-5f7cA:
undetectable		 3bszE-5f7cA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 HIS A 597
ILE A 331
TRP A 596
ARG A 319
 None
 1.46A 3ccfB-5f7cA:
undetectable		 3ccfB-5f7cA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_A_1GNA998_1
(GALECTIN-7)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ASN A 670
ASN A 667
TRP A 528
GLU A 669
 None
 1.44A 3galA-5f7cA:
undetectable		 3galA-5f7cA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 543
GLY A 207
LEU A 245
ILE A 638
ASP A 216
 None
 1.03A 3gwvA-5f7cA:
undetectable		 3gwvA-5f7cA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWW_A_SFXA801_1
(TRANSPORTER)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 543
GLY A 207
LEU A 245
ILE A 638
ASP A 216
 None
 1.02A 3gwwA-5f7cA:
undetectable		 3gwwA-5f7cA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4W_A_MIGA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ASP A 348
ASP A 460
TRP A 520
ASP A 523
PHE A 556
HIS A 588
 None
 0.39A 3l4wA-5f7cA:
28.6		 3l4wA-5f7cA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 PRO A  31
ILE A 153
LEU A 155
THR A  44
 None
 0.83A 3p50A-5f7cA:
undetectable		 3p50A-5f7cA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 PRO A  31
ILE A 153
LEU A 155
THR A  44
 None
 0.83A 3p50B-5f7cA:
undetectable		 3p50B-5f7cA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 PRO A  31
ILE A 153
LEU A 155
THR A  44
 None
 0.83A 3p50C-5f7cA:
undetectable		 3p50C-5f7cA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_D_PFLD320_1
(GLR4197 PROTEIN)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 PRO A  31
ILE A 153
LEU A 155
THR A  44
 None
 0.82A 3p50D-5f7cA:
undetectable		 3p50D-5f7cA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_E_PFLE319_1
(GLR4197 PROTEIN)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 PRO A  31
ILE A 153
LEU A 155
THR A  44
 None
 0.85A 3p50E-5f7cA:
undetectable		 3p50E-5f7cA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_1
(ALPHA-GLUCOSIDASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		8 / 12 ASP A 228
ASP A 348
ASP A 460
ARG A 507
TRP A 520
ASP A 523
PHE A 556
HIS A 588
 None
 0.46A 3phaA-5f7cA:
34.0		 3phaA-5f7cA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		7 / 12 ASP A 228
ASP A 348
ASP A 460
ARG A 507
ASP A 523
PHE A 556
HIS A 588
 None
 0.43A 3phaB-5f7cA:
30.8		 3phaB-5f7cA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_C_ACRC701_1
(ALPHA-GLUCOSIDASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		8 / 12 ASP A 228
ASP A 348
ASP A 460
ARG A 507
TRP A 520
ASP A 523
PHE A 556
HIS A 588
 None
 0.42A 3phaC-5f7cA:
34.3		 3phaC-5f7cA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_D_ACRD701_1
(ALPHA-GLUCOSIDASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		7 / 12 ASP A 228
ASP A 348
ASP A 460
ARG A 507
ASP A 523
PHE A 556
HIS A 588
 None
 0.46A 3phaD-5f7cA:
34.1		 3phaD-5f7cA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_A_ACRA664_1
(ALPHA-GLUCOSIDASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ASP A 348
ARG A 507
TRP A 520
ASP A 523
PHE A 556
HIS A 588
 None
 0.33A 3pocA-5f7cA:
34.4		 3pocA-5f7cA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB664_1
(ALPHA-GLUCOSIDASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ASP A 348
ARG A 507
TRP A 520
ASP A 523
PHE A 556
HIS A 588
 None
 0.35A 3pocB-5f7cA:
32.2		 3pocB-5f7cA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_A_ACRA1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		7 / 12 ASP A 228
ASP A 348
ASP A 460
ARG A 507
ASP A 523
PHE A 556
HIS A 588
 None
 0.62A 3topA-5f7cA:
28.4		 3topA-5f7cA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_B_ACRB1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		7 / 12 ASP A 228
ASP A 348
ASP A 460
ARG A 507
ASP A 523
PHE A 556
HIS A 588
 None
 0.61A 3topB-5f7cA:
28.4		 3topB-5f7cA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A 182
GLN A  48
LEU A  69
LEU A 165
PHE A  13
 None
 1.34A 3vhuA-5f7cA:
undetectable		 3vhuA-5f7cA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W37_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		7 / 12 ASP A 228
ASP A 348
ASP A 460
ARG A 507
ASP A 523
PHE A 556
HIS A 588
 None
 0.44A 3w37A-5f7cA:
32.8		 3w37A-5f7cA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 228
ASN A 234
ASP A 460
ARG A 507
PHE A 556
 None
 1.02A 3welA-5f7cA:
38.7		 3welA-5f7cA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		7 / 12 ASP A 228
ASP A 348
ASP A 460
ARG A 507
ASP A 523
PHE A 556
HIS A 588
 None
 0.44A 3welA-5f7cA:
38.7		 3welA-5f7cA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEM_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ASP A 228
ASN A 234
ASP A 348
ASP A 460
ARG A 507
PHE A 556
 None
 1.02A 3wemA-5f7cA:
33.7		 3wemA-5f7cA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEM_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		7 / 12 ASP A 228
ASP A 348
ASP A 460
ARG A 507
ASP A 523
PHE A 556
HIS A 588
 None
 0.49A 3wemA-5f7cA:
33.7		 3wemA-5f7cA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEN_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ASP A 228
ASN A 234
ASP A 348
ASP A 460
ARG A 507
PHE A 556
 None
 1.01A 3wenA-5f7cA:
32.6		 3wenA-5f7cA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEN_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		7 / 12 ASP A 228
ASP A 348
ASP A 460
ARG A 507
ASP A 523
PHE A 556
HIS A 588
 None
 0.50A 3wenA-5f7cA:
32.6		 3wenA-5f7cA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASN A 233
ASP A 348
ASP A 523
PHE A 556
HIS A 588
 None
 1.47A 3weoA-5f7cA:
29.8		 3weoA-5f7cA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ASP A 228
ASN A 234
ASP A 348
ASP A 460
ARG A 507
PHE A 556
 None
 0.99A 3weoA-5f7cA:
29.8		 3weoA-5f7cA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		7 / 12 ASP A 228
ASP A 348
ASP A 460
ARG A 507
ASP A 523
PHE A 556
HIS A 588
 None
 0.46A 3weoA-5f7cA:
29.8		 3weoA-5f7cA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ILE A  76
TYR A 304
ARG A 299
THR A 302
 None
 1.06A 3wg7A-5f7cA:
undetectable
3wg7J-5f7cA:
undetectable		 3wg7A-5f7cA:
21.92
3wg7J-5f7cA:
6.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B9Z_A_ACRA1818_1
(ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ASP A 348
ASP A 460
ARG A 507
ASP A 523
PHE A 556
HIS A 588
 None
 0.49A 4b9zA-5f7cA:
33.5		 4b9zA-5f7cA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_B_SFYB806_0
(SEPIAPTERIN
REDUCTASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A  51
CYH A  29
PRO A 147
MET A  56
ALA A  58
 None
 1.29A 4hwkB-5f7cA:
undetectable		 4hwkB-5f7cA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_C_SFYC804_0
(SEPIAPTERIN
REDUCTASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A  51
CYH A  29
PRO A 147
MET A  56
ALA A  58
 None
 1.30A 4hwkC-5f7cA:
1.8		 4hwkC-5f7cA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_D_SFYD803_0
(SEPIAPTERIN
REDUCTASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A  51
CYH A  29
PRO A 147
MET A  56
ALA A  58
 None
 1.33A 4hwkD-5f7cA:
1.8		 4hwkD-5f7cA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 LEU A  69
THR A  79
LEU A  83
VAL A 285
 None
 0.86A 4ik7B-5f7cA:
undetectable		 4ik7B-5f7cA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 176
THR A  44
LEU A  69
THR A 194
 None
 1.31A 4mbsB-5f7cA:
undetectable		 4mbsB-5f7cA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 PRO A 677
LEU A 676
GLN A 680
 None
 0.60A 4pevB-5f7cA:
undetectable		 4pevB-5f7cA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 GLY A 288
ASP A 289
GLY A  77
ARG A 296
 None
 1.04A 4z53A-5f7cA:
undetectable
4z53B-5f7cA:
undetectable		 4z53A-5f7cA:
24.48
4z53B-5f7cA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 GLY A 530
SER A 524
VAL A 232
HIS A 551
 None
 1.14A 5ewuA-5f7cA:
undetectable		 5ewuA-5f7cA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 10 GLY A 693
GLY A 679
LEU A 676
LEU A 661
TYR A 655
 None
 1.24A 5hwkA-5f7cA:
undetectable		 5hwkA-5f7cA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 10 GLY A 693
GLY A 679
LEU A 676
LEU A 661
TYR A 655
 None
 1.23A 5hwkB-5f7cA:
undetectable		 5hwkB-5f7cA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEF_A_NBVA1005_1
(NEUTRAL
ALPHA-GLUCOSIDASE AB)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 348
ASP A 460
ASP A 523
PHE A 556
HIS A 588
 None
 0.45A 5iefA-5f7cA:
29.2		 5iefA-5f7cA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEF_A_NBVA1005_2
(NEUTRAL
ALPHA-GLUCOSIDASE AB)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 4 ARG A 507
TRP A 520
ASP A 552
ARG A 586
 None
 0.59A 5iefA-5f7cA:
29.2		 5iefA-5f7cA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_2
(CDL2.3B)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 9 ILE A 181
PRO A 180
VAL A 285
LEU A 155
ILE A 163
 None
 1.42A 5iepA-5f7cA:
undetectable		 5iepA-5f7cA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 VAL A 232
LYS A 214
MET A 215
 None
 1.09A 5nknA-5f7cA:
undetectable		 5nknA-5f7cA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN6_A_MIGA1013_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ASP A 348
ASP A 460
TRP A 520
ASP A 523
PHE A 556
HIS A 588
 None
 0.45A 5nn6A-5f7cA:
37.3		 5nn6A-5f7cA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN8_A_ACRA1015_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		7 / 12 ASP A 228
ASP A 348
ASP A 460
ARG A 507
ASP A 523
PHE A 556
HIS A 588
 None
 0.54A 5nn8A-5f7cA:
30.6		 5nn8A-5f7cA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1401_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		6 / 10 ASP A 460
ARG A 507
TRP A 520
ASP A 523
PHE A 556
HIS A 588
 None
 0.42A 5x7pA-5f7cA:
13.2		 5x7pA-5f7cA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 TYR A 304
ARG A 299
THR A 302
 None
 0.73A 5z84J-5f7cA:
undetectable		 5z84J-5f7cA:
6.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ILE A  76
TYR A 304
ARG A 299
THR A 302
 None
 1.05A 5z84N-5f7cA:
undetectable
5z84W-5f7cA:
undetectable		 5z84N-5f7cA:
21.92
5z84W-5f7cA:
6.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ASP A 228
ASP A 460
ARG A 507
TRP A 520
PHE A 556
HIS A 588
 None
 0.31A 6c9xA-5f7cA:
30.9		 6c9xA-5f7cA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ASP A 228
ASP A 460
ARG A 507
TRP A 520
PHE A 556
HIS A 588
 None
 0.31A 6c9xB-5f7cA:
34.1		 6c9xB-5f7cA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ASP A 460
ARG A 507
TRP A 520
ASP A 523
PHE A 556
HIS A 588
 None
 0.26A 6c9zA-5f7cA:
32.0		 6c9zA-5f7cA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		6 / 12 ASP A 228
ASP A 460
ARG A 507
TRP A 520
PHE A 556
HIS A 588
 None
 0.33A 6c9zB-5f7cA:
30.9		 6c9zB-5f7cA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		7 / 12 ASP A 348
ASP A 460
ARG A 507
TRP A 520
ASP A 523
PHE A 556
HIS A 588
 None
 0.33A 6ca1A-5f7cA:
34.5		 6ca1A-5f7cA:
8.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		7 / 12 ASP A 348
ASP A 460
ARG A 507
TRP A 520
ASP A 523
PHE A 556
HIS A 588
 None
 0.33A 6ca1B-5f7cA:
36.7		 6ca1B-5f7cA:
8.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		7 / 12 ASP A 348
ASP A 460
ARG A 507
TRP A 520
ASP A 523
PHE A 556
HIS A 588
 None
 0.38A 6ca3A-5f7cA:
30.8		 6ca3A-5f7cA:
8.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		7 / 12 ASP A 348
ASP A 460
ARG A 507
TRP A 520
ASP A 523
PHE A 556
HIS A 588
 None
 0.39A 6ca3B-5f7cA:
32.2		 6ca3B-5f7cA:
8.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_2
(-)		 5f7c ALPHA-GLUCOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 222
LEU A 262
GLY A 207
ASN A 481
LYS A 225
 None
 1.02A 6ce2B-5f7cA:
undetectable		 6ce2B-5f7cA:
9.34