SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f7h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA256_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)		 5f7h T-CELL
IMMUNOGLOBULIN AND
MUCIN
DOMAIN-CONTAINING
PROTEIN 4
(Homo
sapiens) 		4 / 7 LEU B  79
THR B  77
LEU B  76
VAL B  55
 None
 0.96A 1jgsA-5f7hB:
undetectable		 1jgsA-5f7hB:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_1
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 5f7h T-CELL
IMMUNOGLOBULIN AND
MUCIN
DOMAIN-CONTAINING
PROTEIN 4
(Homo
sapiens) 		3 / 3 ARG B  64
ARG B  58
ILE B  69
 None
 0.71A 1uobA-5f7hB:
undetectable		 1uobA-5f7hB:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 5f7h T-CELL
IMMUNOGLOBULIN AND
MUCIN
DOMAIN-CONTAINING
PROTEIN 4
(Homo
sapiens) 		3 / 3 ASN B  29
TRP B  24
ASP B 101
 None
None
CA  B 201 ( 3.1A)
 1.28A 4a7tA-5f7hB:
undetectable
4a7tF-5f7hB:
undetectable		 4a7tA-5f7hB:
22.67
4a7tF-5f7hB:
22.67