SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f7o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_1
(FTSJ)		 5f7o METHYLTHIOADENOSINE
PHOSPHORYLASE
(Schistosoma
mansoni) 		3 / 3 ASP A  95
ASP A 202
ASP A 164
 None
 0.66A 1eizA-5f7oA:
undetectable		 1eizA-5f7oA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_1
(FTSJ)		 5f7o METHYLTHIOADENOSINE
PHOSPHORYLASE
(Schistosoma
mansoni) 		3 / 3 ASP A  95
ASP A 202
ASP A 164
 None
 0.65A 1ej0A-5f7oA:
undetectable		 1ej0A-5f7oA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5f7o METHYLTHIOADENOSINE
PHOSPHORYLASE
(Schistosoma
mansoni) 		5 / 10 GLY A  90
PHE A 187
VAL A 204
MET A 206
THR A 229
 ADE  A 301 (-3.5A)
ADE  A 301 (-4.8A)
ADE  A 301 (-4.1A)
ADE  A 301 (-4.3A)
ADE  A 301 (-4.3A)
 0.36A 1pwyE-5f7oA:
22.7		 1pwyE-5f7oA:
26.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 5f7o METHYLTHIOADENOSINE
PHOSPHORYLASE
(Schistosoma
mansoni) 		5 / 12 GLY A  42
ASN A  71
SER A  36
GLY A  10
ILE A   9
 None
 1.18A 1q8jB-5f7oA:
undetectable		 1q8jB-5f7oA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3Q_E_2DIE290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5f7o METHYLTHIOADENOSINE
PHOSPHORYLASE
(Schistosoma
mansoni) 		5 / 10 GLY A  90
PHE A 187
VAL A 204
MET A 206
THR A 229
 ADE  A 301 (-3.5A)
ADE  A 301 (-4.8A)
ADE  A 301 (-4.1A)
ADE  A 301 (-4.3A)
ADE  A 301 (-4.3A)
 0.29A 1v3qE-5f7oA:
23.0		 1v3qE-5f7oA:
26.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_F_SAMF301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5f7o METHYLTHIOADENOSINE
PHOSPHORYLASE
(Schistosoma
mansoni) 		3 / 3 LYS A 197
ASP A 100
CYH A 168
 None
 1.34A 2br4F-5f7oA:
undetectable		 2br4F-5f7oA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_F_SAMF301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5f7o METHYLTHIOADENOSINE
PHOSPHORYLASE
(Schistosoma
mansoni) 		3 / 3 LYS A 235
ASP A 100
CYH A 168
 None
 1.21A 2br4F-5f7oA:
undetectable		 2br4F-5f7oA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_A_ADNA300_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 5f7o METHYLTHIOADENOSINE
PHOSPHORYLASE
(Schistosoma
mansoni) 		5 / 12 ALA A  88
GLY A  90
VAL A 204
MET A 206
VAL A 246
 ADE  A 301 (-4.1A)
ADE  A 301 (-3.5A)
ADE  A 301 (-4.1A)
ADE  A 301 (-4.3A)
ADE  A 301 ( 4.7A)
 0.55A 3f8wA-5f7oA:
23.8		 3f8wA-5f7oA:
26.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_C_ADNC302_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 5f7o METHYLTHIOADENOSINE
PHOSPHORYLASE
(Schistosoma
mansoni) 		5 / 12 ALA A  88
GLY A  90
VAL A 204
MET A 206
VAL A 246
 ADE  A 301 (-4.1A)
ADE  A 301 (-3.5A)
ADE  A 301 (-4.1A)
ADE  A 301 (-4.3A)
ADE  A 301 ( 4.7A)
 0.52A 3f8wC-5f7oA:
24.0		 3f8wC-5f7oA:
26.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5f7o METHYLTHIOADENOSINE
PHOSPHORYLASE
(Schistosoma
mansoni) 		3 / 3 CYH A 172
PRO A  98
ASP A  95
 None
 1.00A 3hlwB-5f7oA:
undetectable		 3hlwB-5f7oA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_2
(BETA-LACTAMASE
CTX-M-14)		 5f7o METHYLTHIOADENOSINE
PHOSPHORYLASE
(Schistosoma
mansoni) 		3 / 3 CYH A 172
PRO A  98
ASP A  95
 None
 1.01A 4pm5A-5f7oA:
undetectable		 4pm5A-5f7oA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)		 5f7o METHYLTHIOADENOSINE
PHOSPHORYLASE
(Schistosoma
mansoni) 		3 / 3 ARG A  54
TYR A 222
GLU A 211
 None
 0.52A 4zzbE-5f7oA:
undetectable		 4zzbE-5f7oA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_D_SAMD301_0
(NS5)		 5f7o METHYLTHIOADENOSINE
PHOSPHORYLASE
(Schistosoma
mansoni) 		5 / 12 GLY A  42
GLU A  41
VAL A 265
ASP A  15
ILE A   8
 None
 0.98A 5njvD-5f7oA:
undetectable		 5njvD-5f7oA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 5f7o METHYLTHIOADENOSINE
PHOSPHORYLASE
(Schistosoma
mansoni) 		3 / 3 HIS A 170
ASP A 100
HIS A 174
 None
 0.64A 5oexA-5f7oA:
undetectable		 5oexA-5f7oA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 5f7o METHYLTHIOADENOSINE
PHOSPHORYLASE
(Schistosoma
mansoni) 		3 / 3 HIS A 170
ASP A 100
HIS A 174
 None
 0.66A 5oexB-5f7oA:
undetectable		 5oexB-5f7oA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 5f7o METHYLTHIOADENOSINE
PHOSPHORYLASE
(Schistosoma
mansoni) 		3 / 3 HIS A 170
ASP A 100
HIS A 174
 None
 0.66A 5oexC-5f7oA:
undetectable		 5oexC-5f7oA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 5f7o METHYLTHIOADENOSINE
PHOSPHORYLASE
(Schistosoma
mansoni) 		3 / 3 HIS A 170
ASP A 100
HIS A 174
 None
 0.65A 5oexD-5f7oA:
undetectable		 5oexD-5f7oA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM2_A_ACTA605_0
(SALICYLATE-AMP
LIGASE)		 5f7o METHYLTHIOADENOSINE
PHOSPHORYLASE
(Schistosoma
mansoni) 		3 / 3 THR A 181
THR A 111
ARG A 114
 None
 1.02A 5wm2A-5f7oA:
2.1		 5wm2A-5f7oA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5f7o METHYLTHIOADENOSINE
PHOSPHORYLASE
(Schistosoma
mansoni) 		4 / 5 ARG A 151
ALA A 150
GLN A 148
ILE A 145
 None
 1.08A 6f6sA-5f7oA:
undetectable
6f6sB-5f7oA:
undetectable		 6f6sA-5f7oA:
14.57
6f6sB-5f7oA:
12.58