SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f7r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 5f7r LMO0178 PROTEIN
(Listeria
monocytogenes) 		4 / 8 ILE E 321
LEU E 317
PHE E 346
GLY E 339
 None
 1.08A 1os6A-5f7rE:
undetectable		 1os6A-5f7rE:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDT_A_VIAA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5f7r LMO0178 PROTEIN
(Listeria
monocytogenes) 		5 / 12 TYR E 188
ILE E 185
VAL E 386
ALA E 383
LEU E 102
 None
 1.11A 1udtA-5f7rE:
undetectable		 1udtA-5f7rE:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 5f7r LMO0178 PROTEIN
(Listeria
monocytogenes) 		3 / 3 GLY E 159
GLU E 175
ASN E 155
 None
 0.57A 1zq9A-5f7rE:
undetectable		 1zq9A-5f7rE:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5f7r LMO0178 PROTEIN
(Listeria
monocytogenes) 		5 / 12 GLU E 304
GLY E 302
ARG E 300
ASP E 303
ALA E 299
 None
 1.21A 2br4B-5f7rE:
undetectable		 2br4B-5f7rE:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5f7r LMO0178 PROTEIN
(Listeria
monocytogenes) 		5 / 12 GLU E 304
GLY E 302
ASP E 303
ALA E 299
ALA E 296
 None
 1.21A 2br4B-5f7rE:
undetectable		 2br4B-5f7rE:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 5f7r LMO0178 PROTEIN
(Listeria
monocytogenes) 		3 / 3 CYH E 256
CYH E 261
HIS E 244
 ZN  E 503 (-2.2A)
ZN  E 503 (-2.3A)
ZN  E 503 ( 3.1A)
 0.84A 2iwkA-5f7rE:
undetectable		 2iwkA-5f7rE:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 5f7r LMO0178 PROTEIN
(Listeria
monocytogenes) 		3 / 3 CYH E 256
CYH E 261
HIS E 244
 ZN  E 503 (-2.2A)
ZN  E 503 (-2.3A)
ZN  E 503 ( 3.1A)
 0.84A 2iwkB-5f7rE:
undetectable		 2iwkB-5f7rE:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 5f7r LMO0178 PROTEIN
(Listeria
monocytogenes) 		5 / 9 ILE E 148
GLY E 147
LEU E  95
SER E 111
LEU E  96
 None
 1.07A 3ai9X-5f7rE:
undetectable		 3ai9X-5f7rE:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_B_CUB1022_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 5f7r LMO0178 PROTEIN
(Listeria
monocytogenes) 		3 / 3 CYH E 256
CYH E 261
HIS E 244
 ZN  E 503 (-2.2A)
ZN  E 503 (-2.3A)
ZN  E 503 ( 3.1A)
 0.77A 3dtuB-5f7rE:
undetectable		 3dtuB-5f7rE:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_D_CUD3_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 5f7r LMO0178 PROTEIN
(Listeria
monocytogenes) 		3 / 3 CYH E 256
CYH E 261
HIS E 244
 ZN  E 503 (-2.2A)
ZN  E 503 (-2.3A)
ZN  E 503 ( 3.1A)
 0.74A 3dtuD-5f7rE:
undetectable		 3dtuD-5f7rE:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ0_X_DXCX75_0
(CYTOCHROME C7)		 5f7r LMO0178 PROTEIN
(Listeria
monocytogenes) 		4 / 7 ILE E 227
LYS E 332
PHE E 212
GLY E 206
 None
 1.14A 3sj0X-5f7rE:
undetectable		 3sj0X-5f7rE:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 5f7r LMO0178 PROTEIN
(Listeria
monocytogenes) 		5 / 11 ILE E 127
ILE E 148
GLY E 147
VAL E 161
GLY E 159
 None
 1.08A 4ac9B-5f7rE:
undetectable
4ac9C-5f7rE:
undetectable		 4ac9B-5f7rE:
23.31
4ac9C-5f7rE:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 5f7r LMO0178 PROTEIN
(Listeria
monocytogenes) 		4 / 7 ILE E 321
LEU E 317
PHE E 346
GLY E 339
 None
 1.04A 4hc3A-5f7rE:
undetectable		 4hc3A-5f7rE:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5f7r LMO0178 PROTEIN
(Listeria
monocytogenes) 		4 / 7 MET E 264
GLU E 263
GLU E 268
GLU E  92
 None
GLC  E 501 (-2.7A)
None
GLC  E 502 (-3.3A)
 1.34A 4mj8C-5f7rE:
undetectable		 4mj8C-5f7rE:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5f7r LMO0178 PROTEIN
(Listeria
monocytogenes) 		5 / 12 ALA E 149
GLY E 381
THR E 100
LEU E  99
LEU E 143
 None
 1.24A 4n48B-5f7rE:
undetectable		 4n48B-5f7rE:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5f7r LMO0178 PROTEIN
(Listeria
monocytogenes) 		5 / 12 ALA E 180
ILE E 148
ALA E 128
VAL E 187
VAL E 146
 None
 0.89A 4nkxA-5f7rE:
undetectable		 4nkxA-5f7rE:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5f7r LMO0178 PROTEIN
(Listeria
monocytogenes) 		5 / 12 THR E 214
GLY E 204
GLY E 206
ALA E 104
THR E 100
 None
 1.12A 4uckB-5f7rE:
undetectable		 4uckB-5f7rE:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWZ_D_010D6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
PEDV MAIN PROTEASE)		 5f7r LMO0178 PROTEIN
(Listeria
monocytogenes) 		3 / 3 MET E 264
HIS E 255
GLY E 243
 None
None
GLC  E 501 ( 4.5A)
 0.79A 5gwzB-5f7rE:
undetectable		 5gwzB-5f7rE:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 5f7r LMO0178 PROTEIN
(Listeria
monocytogenes) 		5 / 10 GLY E 337
GLY E 339
LEU E 340
LEU E 347
ARG E 343
 GLC  E 502 ( 4.9A)
None
None
None
None
 1.27A 5hwkA-5f7rE:
undetectable		 5hwkA-5f7rE:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 5f7r LMO0178 PROTEIN
(Listeria
monocytogenes) 		5 / 10 GLY E 337
GLY E 339
LEU E 340
LEU E 347
ARG E 343
 GLC  E 502 ( 4.9A)
None
None
None
None
 1.27A 5hwkB-5f7rE:
undetectable		 5hwkB-5f7rE:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5f7r LMO0178 PROTEIN
(Listeria
monocytogenes) 		5 / 12 GLY E 311
VAL E 215
LEU E 221
GLY E 318
ILE E 350
 None
 1.17A 5vopB-5f7rE:
3.0		 5vopB-5f7rE:
22.78