SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f7v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_A_NIOA604_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		4 / 5 SER A 223
THR A 220
GLU A 225
GLY A 208
 None
 1.29A 1icrA-5f7vA:
undetectable
1icrB-5f7vA:
undetectable		 1icrA-5f7vA:
19.41
1icrB-5f7vA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_B_NIOB602_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		4 / 5 GLU A 225
GLY A 208
SER A 223
THR A 220
 None
 1.27A 1icrA-5f7vA:
undetectable
1icrB-5f7vA:
undetectable		 1icrA-5f7vA:
19.41
1icrB-5f7vA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_C_NIOC708_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		4 / 5 SER A 223
THR A 220
GLU A 225
GLY A 208
 None
 1.25A 1icvC-5f7vA:
undetectable
1icvD-5f7vA:
undetectable		 1icvC-5f7vA:
19.41
1icvD-5f7vA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_D_NIOD706_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		4 / 5 GLU A 225
GLY A 208
SER A 223
THR A 220
 None
 1.26A 1icvC-5f7vA:
undetectable
1icvD-5f7vA:
undetectable		 1icvC-5f7vA:
19.41
1icvD-5f7vA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_B_BEZB525_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		4 / 5 GLU A 225
GLY A 208
SER A 223
THR A 220
 None
 1.28A 1kqbA-5f7vA:
undetectable
1kqbB-5f7vA:
undetectable		 1kqbA-5f7vA:
20.69
1kqbB-5f7vA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		3 / 3 GLU A 228
ASN A 207
TRP A 171
 None
 1.14A 1r15C-5f7vA:
undetectable		 1r15C-5f7vA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		3 / 3 GLU A 228
ASN A 207
TRP A 171
 None
 1.18A 1r15D-5f7vA:
undetectable		 1r15D-5f7vA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		3 / 3 GLU A 228
ASN A 207
TRP A 171
 None
 1.16A 1r15E-5f7vA:
undetectable		 1r15E-5f7vA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		3 / 3 GLU A 228
ASN A 207
TRP A 171
 None
 1.14A 1r15F-5f7vA:
undetectable		 1r15F-5f7vA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_A_SAMA500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		5 / 11 GLU A 326
ALA A 329
ILE A 331
ASP A 334
PRO A 340
 None
 1.34A 2admA-5f7vA:
undetectable		 2admA-5f7vA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		4 / 7 VAL A 195
THR A 196
THR A 386
LYS A 392
 None
GLC  A 501 ( 4.9A)
None
None
 1.16A 2kotA-5f7vA:
undetectable		 2kotA-5f7vA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		4 / 8 VAL A 195
THR A 196
THR A 386
LYS A 392
 None
GLC  A 501 ( 4.9A)
None
None
 1.10A 2kotB-5f7vA:
undetectable		 2kotB-5f7vA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		4 / 7 ASN A 387
GLU A 391
LEU A 394
TYR A 201
 None
 1.24A 2w8yA-5f7vA:
undetectable		 2w8yA-5f7vA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_B_V2HB602_0
(CYTOCHROME P450 2R1)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		5 / 12 THR A 150
VAL A 242
ALA A 243
ALA A 264
GLU A 174
 None
 1.15A 3dl9B-5f7vA:
undetectable		 3dl9B-5f7vA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		4 / 8 SER A 407
ILE A 221
PHE A 200
GLU A 389
 None
 1.12A 4cx7A-5f7vA:
undetectable
4cx7B-5f7vA:
undetectable		 4cx7A-5f7vA:
20.13
4cx7B-5f7vA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_B_1FLB201_1
(TRANSTHYRETIN)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		4 / 4 LYS A 330
ALA A 329
SER A 323
THR A 342
 None
 1.28A 4i89B-5f7vA:
undetectable		 4i89B-5f7vA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		4 / 6 ILE A 211
THR A 219
VAL A 203
SER A 407
 None
 1.03A 4iaqA-5f7vA:
undetectable		 4iaqA-5f7vA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_2
(DIHYDROFOLATE
REDUCTASE)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		3 / 3 TRP A 379
GLN A  78
THR A  96
 None
 1.04A 4m2xA-5f7vA:
undetectable		 4m2xA-5f7vA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		5 / 12 ALA A 205
ALA A 204
GLN A 206
ALA A 295
ILE A 382
 None
 0.80A 4nqaH-5f7vA:
undetectable		 4nqaH-5f7vA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		3 / 3 GLU A 236
THR A 150
HIS A 267
 None
 0.84A 4q15A-5f7vA:
undetectable		 4q15A-5f7vA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		3 / 3 GLU A 236
THR A 150
HIS A 267
 None
 0.85A 4q15B-5f7vA:
undetectable		 4q15B-5f7vA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		3 / 3 GLU A 236
THR A 150
HIS A 267
 None
 0.83A 4ydqB-5f7vA:
undetectable		 4ydqB-5f7vA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		5 / 12 ILE A 303
GLY A 302
GLU A 313
SER A 111
ILE A 113
 None
 1.40A 5igwA-5f7vA:
undetectable		 5igwA-5f7vA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_2
(CYCLIN-DEPENDENT
KINASE 6)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		3 / 3 LYS A 311
GLN A  66
ASN A  64
 None
 0.97A 5l2tA-5f7vA:
undetectable		 5l2tA-5f7vA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_C_CHDC401_0
(BILE SALT HYDROLASE)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		4 / 8 ILE A  33
LEU A 106
ALA A 107
LEU A 109
 None
 0.78A 5y7pC-5f7vA:
undetectable		 5y7pC-5f7vA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_E_CHDE401_0
(BILE SALT HYDROLASE)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		4 / 8 ILE A  33
LEU A 106
ALA A 107
LEU A 109
 None
 0.81A 5y7pE-5f7vA:
undetectable		 5y7pE-5f7vA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 5f7v LMO0181 PROTEIN
(Listeria
monocytogenes) 		5 / 12 VAL A 149
ASP A 358
SER A 366
LEU A 352
LEU A 339
 None
 1.23A 6ew0F-5f7vA:
undetectable		 6ew0F-5f7vA:
11.81