SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f84'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KLM_A_SPPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 5f84 O-GLUCOSYLTRANSFERAS
E RUMI
(Drosophila
melanogaster) 		5 / 11 LEU A 145
VAL A 137
TRP A 380
LEU A 384
PRO A 141
 None
 1.42A 1klmA-5f84A:
undetectable		 1klmA-5f84A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA888_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 5f84 O-GLUCOSYLTRANSFERAS
E RUMI
COAGULATION FACTOR
IX
(Drosophila
melanogaster;
Homo
sapiens) 		4 / 6 PRO B  55
ALA A 124
GLU A 127
GLU B  83
 None
 1.30A 1qhyA-5f84B:
undetectable		 1qhyA-5f84B:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1433_1
(CHITINASE)		 5f84 O-GLUCOSYLTRANSFERAS
E RUMI
(Drosophila
melanogaster) 		4 / 5 TRP A 184
TYR A 181
ASP A 151
PHE A 122
 None
None
BGC  B 101 (-2.9A)
None
 1.19A 2a3bA-5f84A:
undetectable		 2a3bA-5f84A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 5f84 O-GLUCOSYLTRANSFERAS
E RUMI
(Drosophila
melanogaster) 		5 / 12 ILE A 200
GLY A 190
GLY A 189
ALA A 124
ALA A 183
 UDP  A 501 (-4.5A)
None
None
None
None
 1.08A 3jayA-5f84A:
undetectable		 3jayA-5f84A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		 5f84 O-GLUCOSYLTRANSFERAS
E RUMI
(Drosophila
melanogaster) 		4 / 7 VAL A 251
LEU A 243
PHE A 310
LEU A 333
 None
 1.06A 3qeoB-5f84A:
undetectable		 3qeoB-5f84A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_B_NCTB501_1
(CYTOCHROME P450 2A6)		 5f84 COAGULATION FACTOR
IX
O-GLUCOSYLTRANSFERAS
E RUMI
(Drosophila
melanogaster;
Homo
sapiens) 		4 / 7 ASN B  54
GLY A 190
THR A 185
PHE A 278
 None
None
None
UDP  A 501 ( 3.3A)
 0.91A 4ejjB-5f84B:
undetectable		 4ejjB-5f84B:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA502_0
(RNA POLYMERASE
3D-POL)		 5f84 O-GLUCOSYLTRANSFERAS
E RUMI
(Drosophila
melanogaster) 		3 / 3 ARG A 386
LYS A 385
LYS A 389
 None
 1.32A 4k50A-5f84A:
undetectable		 4k50A-5f84A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE502_0
(RNA POLYMERASE
3D-POL)		 5f84 O-GLUCOSYLTRANSFERAS
E RUMI
(Drosophila
melanogaster) 		3 / 3 ARG A 386
LYS A 385
LYS A 389
 None
 1.23A 4k50E-5f84A:
undetectable		 4k50E-5f84A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI506_0
(RNA POLYMERASE
3D-POL)		 5f84 O-GLUCOSYLTRANSFERAS
E RUMI
(Drosophila
melanogaster) 		3 / 3 ARG A 386
LYS A 385
LYS A 389
 None
 1.28A 4k50I-5f84A:
undetectable		 4k50I-5f84A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K50_A_ACTA1403_0
(L-THREONINE
3-DEHYDROGENASE)		 5f84 O-GLUCOSYLTRANSFERAS
E RUMI
(Drosophila
melanogaster) 		4 / 5 MET A  96
SER A  99
GLY A 164
ALA A 162
 None
 1.08A 5k50A-5f84A:
undetectable		 5k50A-5f84A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M67_C_ACTC504_0
(ADENOSYLHOMOCYSTEINA
SE)		 5f84 O-GLUCOSYLTRANSFERAS
E RUMI
(Drosophila
melanogaster) 		4 / 4 ASP A 238
ILE A 241
ARG A 245
ARG A 232
 None
 1.26A 5m67C-5f84A:
2.6		 5m67C-5f84A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_A_SALA503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 5f84 O-GLUCOSYLTRANSFERAS
E RUMI
(Drosophila
melanogaster) 		4 / 7 THR A 193
PHE A 278
MET A 206
THR A 185
 UDP  A 501 ( 4.6A)
UDP  A 501 ( 3.3A)
SO4  A 502 (-3.7A)
None
 1.24A 5u6mA-5f84A:
7.2		 5u6mA-5f84A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_B_SALB503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 5f84 O-GLUCOSYLTRANSFERAS
E RUMI
(Drosophila
melanogaster) 		4 / 7 THR A 193
PHE A 278
MET A 206
THR A 185
 UDP  A 501 ( 4.6A)
UDP  A 501 ( 3.3A)
SO4  A 502 (-3.7A)
None
 1.28A 5u6mB-5f84A:
6.9		 5u6mB-5f84A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V1T_A_SAMA605_0
(RADICAL SAM)		 5f84 O-GLUCOSYLTRANSFERAS
E RUMI
(Drosophila
melanogaster) 		5 / 12 LEU A 324
VAL A 309
ASN A 289
SER A 171
THR A 173
 None
 1.32A 5v1tA-5f84A:
undetectable		 5v1tA-5f84A:
20.45