SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f8v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN
(Trichomonas
vaginalis) 		3 / 3 ASN A 123
PHE A 151
VAL A 125
 None
 0.87A 1kijA-5f8vA:
undetectable		 1kijA-5f8vA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)		 5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN
(Trichomonas
vaginalis) 		4 / 7 GLN A 236
PHE A 258
MET A 209
ALA A  75
 None
 1.28A 1linA-5f8vA:
undetectable		 1linA-5f8vA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN
(Trichomonas
vaginalis) 		4 / 5 TYR A 350
SER A 348
THR A 158
ASN A 156
 LLP  A 202 ( 4.0A)
None
LLP  A 202 ( 3.0A)
None
 1.35A 1yvpA-5f8vA:
undetectable		 1yvpA-5f8vA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)		 5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN
(Trichomonas
vaginalis) 		4 / 7 GLY A 266
GLY A 265
ALA A 268
ALA A 269
 None
 0.68A 2ha4B-5f8vA:
undetectable		 2ha4B-5f8vA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN
(Trichomonas
vaginalis) 		4 / 5 ILE A 251
PHE A 258
PHE A 204
ILE A  71
 None
 1.15A 2hjhA-5f8vA:
undetectable		 2hjhA-5f8vA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN
(Trichomonas
vaginalis) 		3 / 3 ASP A  97
TYR A  98
LYS A 113
 None
 0.94A 2othA-5f8vA:
undetectable		 2othA-5f8vA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN
(Trichomonas
vaginalis) 		4 / 5 PHE A 327
PHE A 324
LEU A 336
PHE A   9
 None
 1.36A 2y69C-5f8vA:
undetectable
2y69J-5f8vA:
undetectable		 2y69C-5f8vA:
21.27
2y69J-5f8vA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN
(Trichomonas
vaginalis) 		4 / 5 PHE A 327
PHE A 324
LEU A 336
PHE A   9
 None
 1.29A 2y69P-5f8vA:
undetectable
2y69W-5f8vA:
undetectable		 2y69P-5f8vA:
21.27
2y69W-5f8vA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN
(Trichomonas
vaginalis) 		4 / 5 PHE A 327
PHE A 324
LEU A 336
PHE A   9
 None
 1.36A 3abmC-5f8vA:
undetectable
3abmJ-5f8vA:
undetectable		 3abmC-5f8vA:
21.27
3abmJ-5f8vA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN
(Trichomonas
vaginalis) 		4 / 5 PHE A 327
PHE A 324
LEU A 336
PHE A   9
 None
 1.29A 3abmP-5f8vA:
undetectable
3abmW-5f8vA:
undetectable		 3abmP-5f8vA:
21.27
3abmW-5f8vA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN
(Trichomonas
vaginalis) 		4 / 5 PHE A 327
PHE A 324
LEU A 336
PHE A   9
 None
 1.34A 3ag3C-5f8vA:
undetectable
3ag3J-5f8vA:
undetectable		 3ag3C-5f8vA:
21.27
3ag3J-5f8vA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_2
(PHOSPHOLIPASE A2)		 5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN
(Trichomonas
vaginalis) 		5 / 9 VAL A 342
GLY A 338
LYS A 337
THR A 158
GLY A 161
 None
None
None
LLP  A 202 ( 3.0A)
None
 1.13A 3bjwG-5f8vA:
undetectable		 3bjwG-5f8vA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6G_A_IZPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN
(Trichomonas
vaginalis) 		5 / 12 MET A 218
ARG A 234
ILE A  90
VAL A  96
TYR A  98
 None
 1.44A 3p6gA-5f8vA:
undetectable		 3p6gA-5f8vA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5P_A_TACA7101_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN
(Trichomonas
vaginalis) 		5 / 12 VAL A 212
TYR A 233
ILE A 187
ILE A 175
TYR A 152
 None
 1.49A 3q5pA-5f8vA:
undetectable		 3q5pA-5f8vA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN
(Trichomonas
vaginalis) 		4 / 5 ASN A   8
ALA A  15
TYR A 350
ALA A  11
 None
None
LLP  A 202 ( 4.0A)
None
 1.38A 3twpD-5f8vA:
undetectable		 3twpD-5f8vA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN
(Trichomonas
vaginalis) 		5 / 12 GLY A 344
PHE A 308
VAL A 281
ASN A 304
ASN A 156
 None
 1.39A 4a83A-5f8vA:
undetectable		 4a83A-5f8vA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_A_9TPA601_1
(SERUM ALBUMIN)		 5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN
(Trichomonas
vaginalis) 		5 / 12 LEU A  62
PRO A 186
ALA A 272
ILE A 257
GLY A 205
 None
 1.18A 4l9qA-5f8vA:
undetectable		 4l9qA-5f8vA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_B_9TPB601_1
(SERUM ALBUMIN)		 5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN
(Trichomonas
vaginalis) 		5 / 12 LEU A  62
PRO A 186
ALA A 272
ILE A 257
GLY A 205
 None
 1.17A 4l9qB-5f8vA:
undetectable		 4l9qB-5f8vA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN
(Trichomonas
vaginalis) 		4 / 6 PHE A 109
PHE A 167
SER A 124
VAL A 125
 None
 1.00A 5hesA-5f8vA:
undetectable		 5hesA-5f8vA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN
(Trichomonas
vaginalis) 		5 / 12 ILE A 175
GLY A 194
GLU A 111
ALA A 148
TYR A 233
 None
 1.20A 5igvA-5f8vA:
undetectable		 5igvA-5f8vA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN
(Trichomonas
vaginalis) 		4 / 5 PHE A 327
PHE A 324
LEU A 336
PHE A   9
 None
 1.33A 5wauC-5f8vA:
undetectable
5wauJ-5f8vA:
undetectable		 5wauC-5f8vA:
21.27
5wauJ-5f8vA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN
(Trichomonas
vaginalis) 		4 / 5 PHE A 327
PHE A 324
LEU A 336
PHE A   9
 None
 1.31A 5wauc-5f8vA:
undetectable
5wauj-5f8vA:
undetectable		 5wauc-5f8vA:
21.27
5wauj-5f8vA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN
(Trichomonas
vaginalis) 		4 / 5 PHE A 327
PHE A 324
LEU A 336
PHE A   9
 None
 1.27A 5xdqC-5f8vA:
undetectable
5xdqJ-5f8vA:
undetectable		 5xdqC-5f8vA:
21.27
5xdqJ-5f8vA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN
(Trichomonas
vaginalis) 		4 / 5 PHE A 327
PHE A 324
LEU A 336
PHE A   9
 None
 1.28A 5xdqP-5f8vA:
undetectable
5xdqW-5f8vA:
undetectable		 5xdqP-5f8vA:
21.27
5xdqW-5f8vA:
10.51