SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f96'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1867_0
(FPRA)		 5f96 HEAVY CHAIN OF
ANTIBODY CH235.12
(Homo
sapiens) 		4 / 4 ALA H  40
ARG H  38
GLN H  43
GLU H  46
 None
 0.93A 1lqtB-5f96H:
undetectable		 1lqtB-5f96H:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1424_0
(FPRA)		 5f96 HEAVY CHAIN OF
ANTIBODY CH235.12
(Homo
sapiens) 		4 / 4 ALA H  40
ARG H  38
GLN H  43
GLU H  46
 None
 0.93A 1lquB-5f96H:
undetectable		 1lquB-5f96H:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_C_AG2C7004_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 5f96 HEAVY CHAIN OF
ANTIBODY CH235.12
(Homo
sapiens) 		4 / 6 ALA H  88
LEU H  82
LEU H  20
LEU H  67
 None
 0.90A 1mt1D-5f96H:
undetectable
1mt1E-5f96H:
undetectable		 1mt1D-5f96H:
16.67
1mt1E-5f96H:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5f96 HEAVY CHAIN OF
ANTIBODY CH235.12
(Homo
sapiens) 		4 / 5 ARG H  82
MET H  18
THR H  19
LEU H  20
 None
 1.22A 2eimJ-5f96H:
undetectable		 2eimJ-5f96H:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5f96 HEAVY CHAIN OF
ANTIBODY CH235.12
(Homo
sapiens) 		4 / 5 ARG H  82
MET H  18
THR H  19
LEU H  20
 None
 1.30A 2eimW-5f96H:
undetectable		 2eimW-5f96H:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5f96 HEAVY CHAIN OF
ANTIBODY CH235.12
(Homo
sapiens) 		4 / 5 ARG H  82
MET H  18
THR H  19
LEU H  20
 None
 1.09A 3ag1J-5f96H:
undetectable		 3ag1J-5f96H:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5f96 HEAVY CHAIN OF
ANTIBODY CH235.12
(Homo
sapiens) 		4 / 5 ARG H  82
MET H  18
THR H  19
LEU H  20
 None
 1.33A 3ag2J-5f96H:
undetectable		 3ag2J-5f96H:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5f96 HEAVY CHAIN OF
ANTIBODY CH235.12
(Homo
sapiens) 		4 / 5 ARG H  82
MET H  18
THR H  19
LEU H  20
 None
 1.12A 3ag4J-5f96H:
undetectable		 3ag4J-5f96H:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 5f96 HEAVY CHAIN OF
ANTIBODY CH235.12
(Homo
sapiens) 		4 / 5 ILE H  34
PRO H  52
TYR H  33
TYR H  50
 None
 1.27A 3d9lA-5f96H:
undetectable
3d9lY-5f96H:
undetectable		 3d9lA-5f96H:
16.52
3d9lY-5f96H:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5f96 HEAVY CHAIN OF
ANTIBODY CH235.12
(Homo
sapiens) 		4 / 6 LEU H 189
GLY H 190
ALA H 125
PRO H 126
 None
 0.52A 3huoA-5f96H:
undetectable		 3huoA-5f96H:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5f96 HEAVY CHAIN OF
ANTIBODY CH235.12
(Homo
sapiens) 		4 / 5 ARG H  82
MET H  18
THR H  19
LEU H  20
 None
 1.34A 5w97J-5f96H:
undetectable		 5w97J-5f96H:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5f96 HEAVY CHAIN OF
ANTIBODY CH235.12
(Homo
sapiens) 		4 / 5 ARG H  82
MET H  18
THR H  19
LEU H  20
 None
 1.07A 5wauJ-5f96H:
undetectable		 5wauJ-5f96H:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5f96 HEAVY CHAIN OF
ANTIBODY CH235.12
(Homo
sapiens) 		4 / 5 ARG H  82
MET H  18
THR H  19
LEU H  20
 None
 0.88A 5x19J-5f96H:
undetectable		 5x19J-5f96H:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5f96 HEAVY CHAIN OF
ANTIBODY CH235.12
(Homo
sapiens) 		4 / 5 ARG H  82
MET H  18
THR H  19
LEU H  20
 None
 0.90A 5x1bJ-5f96H:
undetectable		 5x1bJ-5f96H:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5f96 HEAVY CHAIN OF
ANTIBODY CH235.12
(Homo
sapiens) 		4 / 6 ARG H  82
MET H  18
THR H  19
LEU H  20
 None
 1.06A 5x1fA-5f96H:
undetectable
5x1fJ-5f96H:
undetectable		 5x1fA-5f96H:
18.16
5x1fJ-5f96H:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5f96 HEAVY CHAIN OF
ANTIBODY CH235.12
(Homo
sapiens) 		4 / 5 ARG H  82
MET H  18
THR H  19
LEU H  20
 None
 1.31A 5x1fW-5f96H:
undetectable		 5x1fW-5f96H:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5f96 HEAVY CHAIN OF
ANTIBODY CH235.12
(Homo
sapiens) 		4 / 5 ARG H  82
MET H  18
THR H  19
LEU H  20
 None
 1.40A 5z86J-5f96H:
undetectable		 5z86J-5f96H:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5f96 HEAVY CHAIN OF
ANTIBODY CH235.12
(Homo
sapiens) 		4 / 5 ARG H  82
MET H  18
THR H  19
LEU H  20
 None
 1.29A 6nknW-5f96H:
undetectable		 6nknW-5f96H:
13.36