SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5f9q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1U_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 5f9q MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN YKNZ
(Bacillus
amyloliquefacien
s) 		5 / 10 ILE A  77
VAL A 142
VAL A 162
GLY A 112
LEU A 122
 None
 1.48A 1s1uA-5f9qA:
4.3		 1s1uA-5f9qA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5f9q MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN YKNZ
(Bacillus
amyloliquefacien
s) 		4 / 7 SER A 177
LEU A  79
PHE A 164
THR A 173
 None
 1.10A 2f78A-5f9qA:
undetectable		 2f78A-5f9qA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5f9q MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN YKNZ
(Bacillus
amyloliquefacien
s) 		4 / 7 SER A 177
LEU A  79
PHE A 164
THR A 173
 None
 1.12A 2f78B-5f9qA:
undetectable		 2f78B-5f9qA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5f9q MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN YKNZ
(Bacillus
amyloliquefacien
s) 		4 / 8 GLY A 193
VAL A 212
VAL A  52
VAL A  55
 None
 0.72A 3fi0B-5f9qA:
undetectable		 3fi0B-5f9qA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5f9q MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN YKNZ
(Bacillus
amyloliquefacien
s) 		4 / 8 GLY A 193
VAL A 212
VAL A  52
VAL A  55
 None
 0.70A 3fi0G-5f9qA:
undetectable		 3fi0G-5f9qA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_Q_TRPQ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5f9q MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN YKNZ
(Bacillus
amyloliquefacien
s) 		4 / 8 GLY A 193
VAL A 212
VAL A  52
VAL A  55
 None
 0.67A 3fi0Q-5f9qA:
undetectable		 3fi0Q-5f9qA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA304_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5f9q MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN YKNZ
(Bacillus
amyloliquefacien
s) 		4 / 4 GLN A 138
PRO A 139
VAL A 140
GLU A 141
 None
 1.20A 3huoA-5f9qA:
undetectable		 3huoA-5f9qA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5f9q MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN YKNZ
(Bacillus
amyloliquefacien
s) 		4 / 8 PHE A 123
SER A 115
MET A 160
VAL A 145
 None
 1.30A 3jx1A-5f9qA:
undetectable
3jx1B-5f9qA:
undetectable		 3jx1A-5f9qA:
19.86
3jx1B-5f9qA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5f9q MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN YKNZ
(Bacillus
amyloliquefacien
s) 		4 / 8 PHE A 123
SER A 115
MET A 160
VAL A 145
 None
 1.33A 3nlyA-5f9qA:
undetectable
3nlyB-5f9qA:
undetectable		 3nlyA-5f9qA:
19.86
3nlyB-5f9qA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5f9q MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN YKNZ
(Bacillus
amyloliquefacien
s) 		4 / 8 PHE A 123
SER A 115
MET A 160
VAL A 145
 None
 1.31A 3rqlA-5f9qA:
2.1
3rqlB-5f9qA:
undetectable		 3rqlA-5f9qA:
19.86
3rqlB-5f9qA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5f9q MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN YKNZ
(Bacillus
amyloliquefacien
s) 		4 / 8 PHE A 123
SER A 115
MET A 160
VAL A 145
 None
 1.31A 4capA-5f9qA:
undetectable
4capB-5f9qA:
undetectable		 4capA-5f9qA:
19.86
4capB-5f9qA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5f9q MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN YKNZ
(Bacillus
amyloliquefacien
s) 		4 / 8 PHE A 123
SER A 115
MET A 160
VAL A 145
 None
 1.32A 4d32A-5f9qA:
undetectable
4d32B-5f9qA:
undetectable		 4d32A-5f9qA:
19.86
4d32B-5f9qA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_1
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 5f9q MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN YKNZ
(Bacillus
amyloliquefacien
s) 		5 / 11 VAL A 181
LEU A  20
GLU A 195
ALA A 196
VAL A  55
 None
 1.25A 4e0fA-5f9qA:
1.2		 4e0fA-5f9qA:
24.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD305_0
(GLUTATHIONE
TRANSFERASE GTE1)		 5f9q MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN YKNZ
(Bacillus
amyloliquefacien
s) 		4 / 4 ILE A  46
LEU A  49
LYS A  50
ASN A  83
 None
 1.46A 4g19D-5f9qA:
undetectable		 4g19D-5f9qA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5f9q MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN YKNZ
(Bacillus
amyloliquefacien
s) 		4 / 8 PHE A 123
SER A 115
MET A 160
VAL A 145
 None
 1.34A 4v3yA-5f9qA:
undetectable
4v3yB-5f9qA:
undetectable		 4v3yA-5f9qA:
19.86
4v3yB-5f9qA:
19.86