SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fa1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_B_ACTB1108_0
(C5A PEPTIDASE)		 5fa1 PUTATIVE N-ACETYL
GLUCOSAMINYL
TRANSFERASE
(Raoultella
terrigena) 		4 / 6 LEU A 392
ASN A 335
ILE A 396
PHE A 339
 None
 0.90A 1xf1B-5fa1A:
undetectable		 1xf1B-5fa1A:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 5fa1 PUTATIVE N-ACETYL
GLUCOSAMINYL
TRANSFERASE
(Raoultella
terrigena) 		6 / 12 LEU A 341
LEU A 204
LEU A 201
ILE A 307
ILE A 324
ALA A 336
 None
 1.42A 2bxqA-5fa1A:
undetectable		 2bxqA-5fa1A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 5fa1 PUTATIVE N-ACETYL
GLUCOSAMINYL
TRANSFERASE
(Raoultella
terrigena) 		5 / 11 ASN A 299
ILE A 324
TYR A 344
ALA A 184
SER A 185
 None
 1.40A 2iyfA-5fa1A:
4.5		 2iyfA-5fa1A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 5fa1 PUTATIVE N-ACETYL
GLUCOSAMINYL
TRANSFERASE
(Raoultella
terrigena) 		5 / 12 ASN A 299
ILE A 324
TYR A 344
ALA A 184
SER A 185
 None
 1.38A 2iyfB-5fa1A:
5.2		 2iyfB-5fa1A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)		 5fa1 PUTATIVE N-ACETYL
GLUCOSAMINYL
TRANSFERASE
(Raoultella
terrigena) 		4 / 6 LEU A 106
THR A 107
ARG A  12
ASP A 232
 None
 0.89A 2wm3A-5fa1A:
undetectable		 2wm3A-5fa1A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZB7_A_NCAA901_0
(PROSTAGLANDIN
REDUCTASE 2)		 5fa1 PUTATIVE N-ACETYL
GLUCOSAMINYL
TRANSFERASE
(Raoultella
terrigena) 		4 / 5 TYR A 340
ILE A 324
LEU A 204
LEU A 308
 None
 1.15A 2zb7A-5fa1A:
2.4		 2zb7A-5fa1A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5fa1 PUTATIVE N-ACETYL
GLUCOSAMINYL
TRANSFERASE
(Raoultella
terrigena) 		4 / 7 PHE A   5
PHE A 105
TYR A   9
GLY A  13
 None
 1.07A 3em0B-5fa1A:
undetectable		 3em0B-5fa1A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)		 5fa1 PUTATIVE N-ACETYL
GLUCOSAMINYL
TRANSFERASE
(Raoultella
terrigena) 		4 / 8 LEU A  82
TYR A   9
PHE A 105
LEU A 113
 None
 1.00A 3i45A-5fa1A:
2.1		 3i45A-5fa1A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5fa1 PUTATIVE N-ACETYL
GLUCOSAMINYL
TRANSFERASE
(Raoultella
terrigena) 		4 / 7 TYR A 344
VAL A 351
ILE A 159
MET A 155
 None
 1.36A 3ms9B-5fa1A:
undetectable		 3ms9B-5fa1A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA2_1
(CYTOCHROME P450 2D6)		 5fa1 PUTATIVE N-ACETYL
GLUCOSAMINYL
TRANSFERASE
(Raoultella
terrigena) 		5 / 11 LEU A 308
THR A 309
SER A 301
GLU A 305
THR A 313
 None
None
C5P  A 501 (-2.6A)
None
None
 1.40A 3tbgA-5fa1A:
undetectable		 3tbgA-5fa1A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 5fa1 PUTATIVE N-ACETYL
GLUCOSAMINYL
TRANSFERASE
(Raoultella
terrigena) 		4 / 7 SER A 123
ILE A 127
THR A  81
THR A  37
 None
 1.06A 3tneB-5fa1A:
undetectable		 3tneB-5fa1A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 5fa1 PUTATIVE N-ACETYL
GLUCOSAMINYL
TRANSFERASE
(Raoultella
terrigena) 		5 / 12 TYR A 172
TYR A 340
VAL A 302
SER A 320
LEU A 247
 None
 1.39A 3vt7A-5fa1A:
undetectable		 3vt7A-5fa1A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1476_0
(MJ0495-LIKE PROTEIN)		 5fa1 PUTATIVE N-ACETYL
GLUCOSAMINYL
TRANSFERASE
(Raoultella
terrigena) 		4 / 5 ILE A 396
ALA A 399
HIS A 373
ARG A 168
 None
 1.07A 4ac9B-5fa1A:
2.6
4ac9C-5fa1A:
2.5		 4ac9B-5fa1A:
22.29
4ac9C-5fa1A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1476_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5fa1 PUTATIVE N-ACETYL
GLUCOSAMINYL
TRANSFERASE
(Raoultella
terrigena) 		4 / 5 ILE A 396
ALA A 399
HIS A 373
ARG A 168
 None
 1.06A 4acaB-5fa1A:
2.8
4acaC-5fa1A:
2.3		 4acaB-5fa1A:
22.29
4acaC-5fa1A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5fa1 PUTATIVE N-ACETYL
GLUCOSAMINYL
TRANSFERASE
(Raoultella
terrigena) 		4 / 7 ILE A 298
THR A 243
VAL A 302
ASP A 280
 None
 1.39A 4iarA-5fa1A:
undetectable		 4iarA-5fa1A:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB304_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 5fa1 PUTATIVE N-ACETYL
GLUCOSAMINYL
TRANSFERASE
(Raoultella
terrigena) 		4 / 6 HIS A  77
ILE A  33
TYR A  79
PHE A  22
 None
 1.34A 4o7gB-5fa1A:
undetectable		 4o7gB-5fa1A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 5fa1 PUTATIVE N-ACETYL
GLUCOSAMINYL
TRANSFERASE
(Raoultella
terrigena) 		4 / 5 PHE A 208
HIS A 205
LEU A 286
PRO A 214
 None
 1.40A 4o8zA-5fa1A:
2.8		 4o8zA-5fa1A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P68_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 5fa1 PUTATIVE N-ACETYL
GLUCOSAMINYL
TRANSFERASE
(Raoultella
terrigena) 		5 / 11 ILE A 236
PHE A 102
SER A 136
ILE A 137
TYR A 238
 None
 1.20A 4p68A-5fa1A:
undetectable		 4p68A-5fa1A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_F_PARF500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 5fa1 PUTATIVE N-ACETYL
GLUCOSAMINYL
TRANSFERASE
(Raoultella
terrigena) 		5 / 11 PHE A 105
SER A 136
GLU A 183
ASP A 174
GLY A 180
 None
 1.42A 4qb9F-5fa1A:
undetectable		 4qb9F-5fa1A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5fa1 PUTATIVE N-ACETYL
GLUCOSAMINYL
TRANSFERASE
(Raoultella
terrigena) 		4 / 5 GLU A 355
THR A 133
HIS A 156
LEU A 173
 None
 1.07A 5axaA-5fa1A:
3.8		 5axaA-5fa1A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5fa1 PUTATIVE N-ACETYL
GLUCOSAMINYL
TRANSFERASE
(Raoultella
terrigena) 		4 / 5 GLU A 355
THR A 133
HIS A 156
LEU A 173
 None
 1.09A 5axaC-5fa1A:
undetectable		 5axaC-5fa1A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 5fa1 PUTATIVE N-ACETYL
GLUCOSAMINYL
TRANSFERASE
(Raoultella
terrigena) 		4 / 6 TYR A  23
GLY A  38
GLU A  39
ASP A  83
 None
 1.34A 5emlA-5fa1A:
2.3		 5emlA-5fa1A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_A_FUAA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5fa1 PUTATIVE N-ACETYL
GLUCOSAMINYL
TRANSFERASE
(Raoultella
terrigena) 		4 / 5 ILE A 197
ILE A 374
HIS A 373
VAL A 370
 None
 0.98A 5jmnA-5fa1A:
undetectable		 5jmnA-5fa1A:
18.05