SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fa9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H9Z_A_RWFA3001_1
(SERUM ALBUMIN)		 5fa9 PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
MSRA
(Treponema
denticola) 		5 / 11 ALA A 243
LEU A 244
LEU A 219
LEU A 291
ALA A 266
 None
 0.85A 1h9zA-5fa9A:
undetectable		 1h9zA-5fa9A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		 5fa9 PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
MSRA
(Treponema
denticola) 		5 / 11 ALA A 243
LEU A 244
LEU A 219
LEU A 291
ALA A 266
 None
 0.91A 1ha2A-5fa9A:
undetectable		 1ha2A-5fa9A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 5fa9 PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
MSRA
(Treponema
denticola) 		5 / 11 ASN A 287
SER A 261
GLY A 265
GLY A 264
ASP A 212
 None
 1.20A 1ho5A-5fa9A:
undetectable		 1ho5A-5fa9A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 5fa9 PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
MSRA
(Treponema
denticola) 		4 / 7 LEU A   7
TYR A  58
MET A 103
ILE A 107
 None
 0.89A 1tuvA-5fa9A:
2.9		 1tuvA-5fa9A:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 5fa9 PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
MSRA
(Treponema
denticola) 		4 / 5 GLY A 305
PRO A 218
VAL A 211
ILE A 294
 None
 0.97A 2aoiA-5fa9A:
undetectable		 2aoiA-5fa9A:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U52_A_CUA515_0
(PHENOL HYDROXYLASE
COMPONENT PHL
PHENOL HYDROXYLASE
COMPONENT PHN)		 5fa9 PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
MSRA
(Treponema
denticola) 		3 / 3 HIS A 131
HIS A  50
ILE A 133
 None
 0.78A 3u52A-5fa9A:
undetectable
3u52C-5fa9A:
undetectable		 3u52A-5fa9A:
20.98
3u52C-5fa9A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_A_ACTA708_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 5fa9 PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
MSRA
(Treponema
denticola) 		3 / 3 GLY A 264
GLY A 265
GLN A 189
 None
 0.39A 5imsA-5fa9A:
undetectable		 5imsA-5fa9A:
19.65