SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5far'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)		 5far 7,8-DIHYDRONEOPTERIN
ALDOLASE
(Bacillus
cereus) 		5 / 9 LEU A  32
ILE A  95
PHE A  11
VAL A  63
LEU A  59
 None
 1.24A 1e7aB-5farA:
undetectable		 1e7aB-5farA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 5far 7,8-DIHYDRONEOPTERIN
ALDOLASE
(Bacillus
cereus) 		4 / 5 VAL A  64
VAL A  63
THR A  68
ARG A  67
 None
 1.19A 3bjwC-5farA:
undetectable		 3bjwC-5farA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 5far 7,8-DIHYDRONEOPTERIN
ALDOLASE
(Bacillus
cereus) 		5 / 12 ARG A 117
VAL A  30
ASP A  82
ILE A  79
ASN A  78
 None
 1.34A 3jayA-5farA:
undetectable		 3jayA-5farA:
7.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5far 7,8-DIHYDRONEOPTERIN
ALDOLASE
(Bacillus
cereus) 		4 / 6 VAL A  72
SER A  74
ARG A 117
ILE A  79
 None
 0.93A 5jw1B-5farA:
undetectable		 5jw1B-5farA:
15.69