SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fbh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 ILE B 223
GLY B 219
SER B 170
TYR B 489
MET B 197
 None
None
TCR  B 609 (-2.8A)
None
None
 1.25A 1fm6X-5fbhB:
undetectable		 1fm6X-5fbhB:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 ILE B 292
ILE B 528
ILE B 523
LEU B 521
ILE B 491
 None
 0.99A 1oipA-5fbhB:
undetectable		 1oipA-5fbhB:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_A_STRA301_1
(MINERALOCORTICOID
RECEPTOR)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN B 155
LEU B 157
ALA B 154
GLN B 164
LEU B  37
 None
 1.17A 2aa5A-5fbhB:
undetectable		 2aa5A-5fbhB:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN B 155
LEU B 157
ALA B 154
GLN B 164
LEU B  37
 None
 1.16A 2aa5B-5fbhB:
undetectable		 2aa5B-5fbhB:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN B 155
LEU B 157
ALA B 154
GLN B 164
LEU B  37
 None
 1.21A 2aa6A-5fbhB:
undetectable		 2aa6A-5fbhB:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU B 156
ASN B 155
LEU B 157
ALA B 154
GLN B 164
 None
 1.38A 2aa6A-5fbhB:
undetectable		 2aa6A-5fbhB:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_B_STRB402_1
(MINERALOCORTICOID
RECEPTOR)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN B 155
LEU B 157
ALA B 154
GLN B 164
LEU B  37
 None
 1.20A 2aa6B-5fbhB:
undetectable		 2aa6B-5fbhB:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1291_1
(FICOLIN-2)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		4 / 4 ASP B 275
LEU B 304
GLY B 273
ARG B  62
 None
 1.31A 2j2pD-5fbhB:
undetectable
2j2pE-5fbhB:
undetectable		 2j2pD-5fbhB:
17.89
2j2pE-5fbhB:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_E_SAME1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 GLY B 143
GLY B  36
ASN B 419
ALA B 168
THR B 111
 None
None
None
TCR  B 609 (-4.1A)
None
 1.20A 2vdvE-5fbhB:
undetectable		 2vdvE-5fbhB:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_F_SAMF1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 11 GLY B 143
GLY B  36
ASN B 419
ALA B 168
THR B 111
 None
None
None
TCR  B 609 (-4.1A)
None
 1.20A 2vdvF-5fbhB:
undetectable		 2vdvF-5fbhB:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 ILE B 528
GLU B 525
PHE B 204
ALA B 194
ILE B 318
 None
 1.25A 2xkwB-5fbhB:
undetectable		 2xkwB-5fbhB:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		4 / 6 ILE B 427
ILE B 327
TYR B 418
LEU B 464
 None
 0.89A 3adsA-5fbhB:
undetectable		 3adsA-5fbhB:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DGQ_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		4 / 5 ARG B  66
ILE B 416
TYR B 167
THR B 186
 TCR  B 609 ( 3.6A)
BCT  B 604 (-4.5A)
None
None
 1.49A 3dgqA-5fbhB:
undetectable		 3dgqA-5fbhB:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU B  34
GLY B  35
ILE B 427
ALA B 457
LEU B 464
 None
 0.96A 3gwvA-5fbhB:
undetectable		 3gwvA-5fbhB:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 SER B 170
LEU B 276
ASP B 275
SER B 296
ILE B 305
 TCR  B 609 (-2.8A)
None
None
None
None
 1.23A 3ko0M-5fbhB:
undetectable
3ko0N-5fbhB:
undetectable
3ko0O-5fbhB:
undetectable
3ko0P-5fbhB:
undetectable		 3ko0M-5fbhB:
10.00
3ko0N-5fbhB:
10.00
3ko0O-5fbhB:
10.00
3ko0P-5fbhB:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_C_P77C203_1
(PROTEIN S100-A4)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 10 SER B 170
SER B 296
ILE B 305
LEU B 276
ASP B 275
 TCR  B 609 (-2.8A)
None
None
None
None
 1.25A 3m0wC-5fbhB:
undetectable
3m0wD-5fbhB:
undetectable
3m0wE-5fbhB:
undetectable
3m0wF-5fbhB:
undetectable		 3m0wC-5fbhB:
9.68
3m0wD-5fbhB:
9.68
3m0wE-5fbhB:
9.68
3m0wF-5fbhB:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		4 / 8 SER B 170
SER B 296
LEU B 276
ASP B 275
 TCR  B 609 (-2.8A)
None
None
None
 0.86A 3m0wE-5fbhB:
undetectable
3m0wF-5fbhB:
undetectable
3m0wG-5fbhB:
undetectable
3m0wH-5fbhB:
undetectable		 3m0wE-5fbhB:
9.68
3m0wF-5fbhB:
9.68
3m0wG-5fbhB:
9.68
3m0wH-5fbhB:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_F_P77F203_1
(PROTEIN S100-A4)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 9 LEU B 276
ASP B 275
SER B 296
ILE B 305
SER B 170
 None
None
None
None
TCR  B 609 (-2.8A)
 1.27A 3m0wC-5fbhB:
undetectable
3m0wD-5fbhB:
undetectable
3m0wE-5fbhB:
undetectable
3m0wF-5fbhB:
undetectable		 3m0wC-5fbhB:
9.68
3m0wD-5fbhB:
9.68
3m0wE-5fbhB:
9.68
3m0wF-5fbhB:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_H_P77H203_1
(PROTEIN S100-A4)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 10 LEU B 276
ASP B 275
SER B 296
ILE B 305
SER B 170
 None
None
None
None
TCR  B 609 (-2.8A)
 1.35A 3m0wE-5fbhB:
undetectable
3m0wF-5fbhB:
undetectable
3m0wG-5fbhB:
undetectable
3m0wH-5fbhB:
undetectable		 3m0wE-5fbhB:
9.68
3m0wF-5fbhB:
9.68
3m0wG-5fbhB:
9.68
3m0wH-5fbhB:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_I_P77I203_1
(PROTEIN S100-A4)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 10 LEU B 276
ASP B 275
SER B 296
ILE B 305
SER B 170
 None
None
None
None
TCR  B 609 (-2.8A)
 1.33A 3m0wA-5fbhB:
undetectable
3m0wB-5fbhB:
undetectable
3m0wI-5fbhB:
undetectable
3m0wJ-5fbhB:
undetectable		 3m0wA-5fbhB:
9.68
3m0wB-5fbhB:
9.68
3m0wI-5fbhB:
9.68
3m0wJ-5fbhB:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		3 / 3 PHE B  42
SER B 302
SER B 303
 None
 0.98A 3ufgB-5fbhB:
undetectable		 3ufgB-5fbhB:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_A_ZMRA700_1
(NEURAMINIDASE)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 ASP B  99
GLU B 350
ALA B  26
ASN B 345
TYR B  63
 None
 1.34A 4cpnA-5fbhB:
undetectable		 4cpnA-5fbhB:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_1
(NEURAMINIDASE)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 ASP B  99
GLU B 350
ALA B  26
ASN B 345
TYR B  63
 None
 1.26A 4cpzG-5fbhB:
undetectable		 4cpzG-5fbhB:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ENH_A_FVXA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 PHE B 183
ILE B 187
GLY B 148
ALA B 168
THR B 145
 None
None
None
TCR  B 609 (-4.1A)
CL  B 605 ( 3.9A)
 1.13A 4enhA-5fbhB:
undetectable		 4enhA-5fbhB:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1102_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		4 / 7 PHE B 333
ILE B  97
TYR B  95
HIS B 344
 None
 1.19A 4g5jA-5fbhB:
undetectable		 4g5jA-5fbhB:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 LEU B 157
VAL B 141
MET B  74
PHE B  38
THR B 100
 None
None
None
None
CL  B 605 (-2.8A)
 1.34A 4iaqA-5fbhB:
undetectable		 4iaqA-5fbhB:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 11 ARG B 185
ALA B 168
VAL B 420
MET B  74
ILE B 427
 None
TCR  B 609 (-4.1A)
None
None
None
 1.26A 4j4vA-5fbhB:
undetectable		 4j4vA-5fbhB:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		4 / 5 LEU B  88
PRO B  89
LEU B  91
ILE B  32
 MG  B 603 (-4.5A)
None
None
None
 0.91A 4klrA-5fbhB:
3.0		 4klrA-5fbhB:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_A_ACTA1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		4 / 5 ARG B 220
GLY B 219
GLY B 222
PRO B 221
 None
 0.94A 4u9uA-5fbhB:
4.6		 4u9uA-5fbhB:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_A_ACTA1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		4 / 5 GLY B 219
ALA B 213
GLY B 222
PRO B 221
 None
 0.88A 4u9uA-5fbhB:
4.6		 4u9uA-5fbhB:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		4 / 5 ARG B 220
GLY B 219
GLY B 222
PRO B 221
 None
 0.92A 4u9uB-5fbhB:
3.5		 4u9uB-5fbhB:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 ASN B 512
VAL B 513
TYR B 510
ILE B 318
ASN B 524
 None
 1.22A 4xueA-5fbhB:
4.7		 4xueA-5fbhB:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_1
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 ALA B 295
SER B 296
VAL B 269
GLU B 277
PHE B  42
 None
 1.06A 4zj8A-5fbhB:
4.4		 4zj8A-5fbhB:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EU8_B_010B6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		4 / 5 ASN B 468
LEU B 467
HIS B 429
THR B 470
 NAG  B 608 (-1.9A)
None
None
None
 1.50A 5eu8A-5fbhB:
0.6		 5eu8A-5fbhB:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_B_032B401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		6 / 12 GLY B  67
ALA B 168
TYR B 167
ALA B 144
ASP B  99
GLY B 219
 None
TCR  B 609 (-4.1A)
None
CL  B 605 ( 3.8A)
None
None
 1.35A 5hesB-5fbhB:
undetectable		 5hesB-5fbhB:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHN_B_SAMB1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 MET B 473
GLY B 474
SER B 426
ASN B 472
TYR B 421
 None
 1.40A 5jhnB-5fbhB:
undetectable		 5jhnB-5fbhB:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JJ0_B_SAMB1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 MET B 473
GLY B 474
SER B 426
ASN B 472
TYR B 421
 None
 1.41A 5jj0B-5fbhB:
undetectable		 5jj0B-5fbhB:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TTF_A_SAMA1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 11 MET B 473
GLY B 474
SER B 426
ASN B 472
TYR B 421
 None
 1.36A 5ttfA-5fbhB:
undetectable		 5ttfA-5fbhB:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TTF_B_SAMB1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 MET B 473
GLY B 474
SER B 426
ASN B 472
TYR B 421
 None
 1.37A 5ttfB-5fbhB:
undetectable		 5ttfB-5fbhB:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TTF_D_SAMD1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 11 MET B 473
GLY B 474
SER B 426
ASN B 472
TYR B 421
 None
 1.39A 5ttfD-5fbhB:
undetectable		 5ttfD-5fbhB:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TTG_B_SAMB1301_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 11 MET B 473
GLY B 474
SER B 426
ASN B 472
TYR B 421
 None
 1.37A 5ttgB-5fbhB:
undetectable		 5ttgB-5fbhB:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUY_A_SAMA1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 MET B 473
GLY B 474
SER B 426
ASN B 472
TYR B 421
 None
 1.35A 5tuyA-5fbhB:
undetectable		 5tuyA-5fbhB:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUY_B_SAMB1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 MET B 473
GLY B 474
SER B 426
ASN B 472
TYR B 421
 None
 1.34A 5tuyB-5fbhB:
undetectable		 5tuyB-5fbhB:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUZ_A_SAMA3001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 MET B 473
GLY B 474
SER B 426
ASN B 472
TYR B 421
 None
 1.39A 5tuzA-5fbhB:
undetectable		 5tuzA-5fbhB:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUZ_B_SAMB3001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 MET B 473
GLY B 474
SER B 426
ASN B 472
TYR B 421
 None
 1.38A 5tuzB-5fbhB:
undetectable		 5tuzB-5fbhB:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V9I_A_SAMA1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 MET B 473
GLY B 474
SER B 426
ASN B 472
TYR B 421
 None
 1.38A 5v9iA-5fbhB:
undetectable		 5v9iA-5fbhB:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V9I_C_SAMC1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 11 MET B 473
GLY B 474
SER B 426
ASN B 472
TYR B 421
 None
 1.39A 5v9iC-5fbhB:
undetectable		 5v9iC-5fbhB:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V9J_A_SAMA1301_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 MET B 473
GLY B 474
SER B 426
ASN B 472
TYR B 421
 None
 1.36A 5v9jA-5fbhB:
undetectable		 5v9jA-5fbhB:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V9J_B_SAMB1301_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 MET B 473
GLY B 474
SER B 426
ASN B 472
TYR B 421
 None
 1.36A 5v9jB-5fbhB:
undetectable		 5v9jB-5fbhB:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VSC_A_SAMA1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 MET B 473
GLY B 474
SER B 426
ASN B 472
TYR B 421
 None
 1.37A 5vscA-5fbhB:
undetectable		 5vscA-5fbhB:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VSC_B_SAMB1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 MET B 473
GLY B 474
SER B 426
ASN B 472
TYR B 421
 None
 1.36A 5vscB-5fbhB:
undetectable		 5vscB-5fbhB:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VSD_A_SAMA3001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 MET B 473
GLY B 474
SER B 426
ASN B 472
TYR B 421
 None
 1.37A 5vsdA-5fbhB:
undetectable		 5vsdA-5fbhB:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VSD_B_SAMB3001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 MET B 473
GLY B 474
SER B 426
ASN B 472
TYR B 421
 None
 1.35A 5vsdB-5fbhB:
undetectable		 5vsdB-5fbhB:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VSE_A_SAMA1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 MET B 473
GLY B 474
SER B 426
ASN B 472
TYR B 421
 None
 1.35A 5vseA-5fbhB:
undetectable		 5vseA-5fbhB:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VSE_B_SAMB1505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 MET B 473
GLY B 474
SER B 426
ASN B 472
TYR B 421
 None
 1.36A 5vseB-5fbhB:
undetectable		 5vseB-5fbhB:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VSF_A_SAMA3001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 MET B 473
GLY B 474
SER B 426
ASN B 472
TYR B 421
 None
 1.37A 5vsfA-5fbhB:
undetectable		 5vsfA-5fbhB:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VSF_B_SAMB3001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		5 / 12 MET B 473
GLY B 474
SER B 426
ASN B 472
TYR B 421
 None
 1.34A 5vsfB-5fbhB:
undetectable		 5vsfB-5fbhB:
18.39