SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fbz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDS_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 VAL A 420
LEU A 367
GLY A 423
PRO A 424
SER A 324
 None
 1.36A 1fdsA-5fbzA:
3.7		 1fdsA-5fbzA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_A_115A2_2
(HMG-COA REDUCTASE)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		4 / 8 HIS A 270
ASN A 274
LEU A 315
LEU A 311
 None
 0.65A 1hwiB-5fbzA:
undetectable		 1hwiB-5fbzA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_1
(HMG-COA REDUCTASE)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		4 / 8 HIS A 270
ASN A 274
LEU A 315
LEU A 311
 None
 0.60A 1hwiC-5fbzA:
undetectable		 1hwiC-5fbzA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_0
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 PHE A  93
ALA A  73
SER A 128
GLY A  67
LEU A  56
 None
 1.26A 1kglA-5fbzA:
undetectable		 1kglA-5fbzA:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A  86
GLY A  78
SER A 228
LEU A  33
LEU A  91
 None
None
5VV  A   1 ( 3.0A)
None
None
 1.10A 1rjdA-5fbzA:
undetectable		 1rjdA-5fbzA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A  86
GLY A  78
SER A 228
LEU A  33
LEU A  91
 None
None
5VV  A   1 ( 3.0A)
None
None
 1.10A 1rjdB-5fbzA:
2.2		 1rjdB-5fbzA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A  86
GLY A  78
SER A 228
LEU A  33
LEU A  91
 None
None
5VV  A   1 ( 3.0A)
None
None
 1.08A 1rjdC-5fbzA:
2.2		 1rjdC-5fbzA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ILE A 259
GLY A 252
ALA A 202
VAL A  72
ALA A 158
 None
 1.05A 1sg9C-5fbzA:
undetectable		 1sg9C-5fbzA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_A_RBFA296_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 11 VAL A  28
ASN A 127
LEU A 106
ILE A  96
ASP A  30
 None
 1.45A 1t6zA-5fbzA:
undetectable		 1t6zA-5fbzA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_1
(CYTOCHROME P450 2C8)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 SER A 347
ASN A 400
ALA A 221
THR A 184
VAL A 295
 None
 1.31A 2nniA-5fbzA:
undetectable		 2nniA-5fbzA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		3 / 3 PRO A 421
ASN A 365
ARG A 149
 None
 0.97A 2qeuB-5fbzA:
undetectable		 2qeuB-5fbzA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z2P_B_DOLB2003_1
(VIRGINIAMYCIN B
LYASE)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 10 PRO A  65
ASN A  63
ASN A  66
GLY A  36
SER A  95
 None
 1.13A 2z2pA-5fbzA:
0.0
2z2pB-5fbzA:
0.0		 2z2pA-5fbzA:
21.87
2z2pB-5fbzA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_B_SAMB501_0
(SPERMIDINE SYNTHASE)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 LEU A 348
ASP A 368
VAL A 415
GLY A 423
ASP A 366
 None
CA  A 602 (-3.3A)
None
None
CA  A 602 (-3.1A)
 0.88A 3bwcB-5fbzA:
undetectable		 3bwcB-5fbzA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ASN A 400
GLY A 381
LEU A 367
LEU A 429
PHE A 402
 None
 1.41A 3cldA-5fbzA:
undetectable		 3cldA-5fbzA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_B_V2HB602_0
(CYTOCHROME P450 2R1)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 VAL A 264
ALA A 261
ALA A  10
GLU A 269
THR A 154
 None
 1.23A 3dl9B-5fbzA:
undetectable		 3dl9B-5fbzA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		4 / 7 THR A 412
GLU A 414
VAL A 370
THR A 372
 None
 0.59A 3em0B-5fbzA:
undetectable		 3em0B-5fbzA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHX_A_PXLA313_1
(PYRIDOXAL KINASE)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		4 / 4 SER A 231
HIS A  68
THR A  31
VAL A  72
 None
 1.32A 3fhxA-5fbzA:
3.7		 3fhxA-5fbzA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A 158
VAL A  72
GLY A  74
ALA A  73
LEU A  91
 None
None
5VV  A   1 ( 4.8A)
None
None
 0.94A 3ln1A-5fbzA:
undetectable		 3ln1A-5fbzA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A 158
VAL A  72
GLY A  74
ALA A  73
LEU A  91
 None
None
5VV  A   1 ( 4.8A)
None
None
 0.93A 3ln1B-5fbzA:
undetectable		 3ln1B-5fbzA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A 158
VAL A  72
GLY A  74
ALA A  73
LEU A  91
 None
None
5VV  A   1 ( 4.8A)
None
None
 0.94A 3ln1C-5fbzA:
undetectable		 3ln1C-5fbzA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A 265
VAL A  76
GLY A  74
ALA A  73
LEU A  33
 None
None
5VV  A   1 ( 4.8A)
None
None
 1.08A 3ln1C-5fbzA:
undetectable		 3ln1C-5fbzA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A 158
VAL A  72
GLY A  74
ALA A  73
LEU A  91
 None
None
5VV  A   1 ( 4.8A)
None
None
 0.93A 3ln1D-5fbzA:
0.6		 3ln1D-5fbzA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A 265
VAL A  76
GLY A  74
ALA A  73
LEU A  33
 None
None
5VV  A   1 ( 4.8A)
None
None
 1.08A 3ln1D-5fbzA:
0.6		 3ln1D-5fbzA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		4 / 6 GLY A 182
VAL A 201
SER A 205
THR A 184
 None
 0.70A 3tj7A-5fbzA:
undetectable
3tj7B-5fbzA:
undetectable		 3tj7A-5fbzA:
17.97
3tj7B-5fbzA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		4 / 6 GLY A 182
VAL A 201
SER A 205
THR A 184
 None
 0.69A 3tj7C-5fbzA:
undetectable
3tj7D-5fbzA:
undetectable		 3tj7C-5fbzA:
17.97
3tj7D-5fbzA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		3 / 3 ASN A 365
ALA A 353
ARG A 149
 None
 0.79A 3tj7C-5fbzA:
undetectable
3tj7D-5fbzA:
undetectable		 3tj7C-5fbzA:
17.97
3tj7D-5fbzA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		4 / 6 VAL A 201
SER A 205
THR A 184
GLY A 182
 None
 0.69A 3tj7C-5fbzA:
undetectable
3tj7D-5fbzA:
undetectable		 3tj7C-5fbzA:
17.97
3tj7D-5fbzA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6D_A_SAMA1350_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 GLY A  84
GLY A  74
ILE A 259
ALA A  80
ASP A   2
 5VV  A   1 ( 4.4A)
5VV  A   1 ( 4.8A)
None
None
5VV  A   1 ( 4.7A)
 1.07A 4a6dA-5fbzA:
2.4		 4a6dA-5fbzA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		3 / 3 ASN A 397
TRP A 350
ASP A 218
 None
 1.31A 4a7tA-5fbzA:
undetectable
4a7tF-5fbzA:
undetectable		 4a7tA-5fbzA:
17.66
4a7tF-5fbzA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		4 / 7 ARG A 214
THR A 180
THR A 210
GLY A 208
 None
 0.96A 4eq4A-5fbzA:
undetectable		 4eq4A-5fbzA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		4 / 7 ARG A 214
THR A 180
THR A 210
GLY A 208
 None
 0.93A 4eqlA-5fbzA:
undetectable		 4eqlA-5fbzA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		4 / 7 ARG A 214
THR A 180
THR A 210
GLY A 208
 None
 0.92A 4eqlB-5fbzA:
undetectable		 4eqlB-5fbzA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_B_SAMB301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 LEU A 315
GLU A 269
GLY A  21
PHE A  17
ALA A 265
 None
 1.41A 4pclB-5fbzA:
undetectable		 4pclB-5fbzA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		3 / 3 ILE A   7
ASP A  11
ARG A 188
 None
None
5VV  A   1 ( 3.6A)
 0.83A 4pstA-5fbzA:
undetectable		 4pstA-5fbzA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_F_SAMF301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 GLY A  67
GLY A  32
LEU A  33
ALA A 248
ASP A  34
 None
 0.96A 5c0oF-5fbzA:
undetectable		 5c0oF-5fbzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ILE A  96
HIS A  68
ALA A  73
LEU A  77
GLY A 262
 None
 1.00A 5igtA-5fbzA:
undetectable		 5igtA-5fbzA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		3 / 3 GLY A 394
ASP A 393
ASN A 400
 CA  A 602 ( 4.4A)
None
None
 0.56A 5jglA-5fbzA:
undetectable		 5jglA-5fbzA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A 158
VAL A  72
GLY A  74
ALA A  73
LEU A  91
 None
None
5VV  A   1 ( 4.8A)
None
None
 0.94A 5jw1A-5fbzA:
undetectable		 5jw1A-5fbzA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A 158
VAL A  72
GLY A  74
ALA A  73
LEU A  91
 None
None
5VV  A   1 ( 4.8A)
None
None
 0.94A 5jw1B-5fbzA:
undetectable		 5jw1B-5fbzA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A 158
VAL A  72
GLY A  74
ALA A  73
LEU A  91
 None
None
5VV  A   1 ( 4.8A)
None
None
 0.93A 5kirA-5fbzA:
undetectable		 5kirA-5fbzA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A 158
VAL A  72
GLY A  74
ALA A  73
LEU A  91
 None
None
5VV  A   1 ( 4.8A)
None
None
 0.96A 5kirB-5fbzA:
undetectable		 5kirB-5fbzA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 SER A  75
GLY A 251
GLY A 223
ASN A 161
HIS A  68
 5VV  A   1 ( 2.6A)
None
None
None
None
 1.07A 5kocB-5fbzA:
undetectable		 5kocB-5fbzA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		3 / 3 SER A 141
ALA A 175
THR A 180
 None
 0.71A 5n0xB-5fbzA:
1.0		 5n0xB-5fbzA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA901_0
(MRNA CAPPING ENZYME
P5)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 11 VAL A 422
GLY A 423
ASP A 352
ALA A 353
ASN A 419
 None
 1.06A 5x6yA-5fbzA:
undetectable		 5x6yA-5fbzA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC901_0
(MRNA CAPPING ENZYME
P5)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 11 VAL A 422
GLY A 423
ASP A 352
ALA A 353
ASN A 419
 None
 1.00A 5x6yC-5fbzA:
undetectable		 5x6yC-5fbzA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_0
(CYTOCHROME P450 1A1)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ASN A 400
PHE A 299
GLY A 307
ILE A 179
LEU A 288
 None
 1.13A 6dwnC-5fbzA:
undetectable		 6dwnC-5fbzA:
13.42