SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fc9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5fc9 BLUE (TYPE 1) COPPER
DOMAIN PROTEIN
(Nitrosopumilus
maritimus) 		4 / 8 ASN A1059
SER A1060
VAL A1054
PHE A1085
 None
 0.59A 2wekA-5fc9A:
undetectable		 2wekA-5fc9A:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5fc9 BLUE (TYPE 1) COPPER
DOMAIN PROTEIN
(Nitrosopumilus
maritimus) 		4 / 8 ASN A1059
SER A1060
VAL A1054
PHE A1085
 None
 0.62A 2wekB-5fc9A:
undetectable		 2wekB-5fc9A:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 5fc9 BLUE (TYPE 1) COPPER
DOMAIN PROTEIN
(Nitrosopumilus
maritimus) 		4 / 8 HIS A1043
HIS A1086
ASP A1039
GLY A1010
 CU  A1401 (-3.0A)
CU  A1401 (-3.1A)
None
None
 0.80A 3c0zB-5fc9A:
undetectable		 3c0zB-5fc9A:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 5fc9 BLUE (TYPE 1) COPPER
DOMAIN PROTEIN
(Nitrosopumilus
maritimus) 		5 / 11 VAL A1072
PHE A1073
ILE A1005
LEU A1063
ALA A1003
 None
 1.38A 4m83A-5fc9A:
undetectable		 4m83A-5fc9A:
18.91