SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fcc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZQ_A_PCFA954_0
(CATECHOL
1,2-DIOXYGENASE)		 5fcc HUTD
(Pseudomonas
fluorescens) 		5 / 9 THR A  28
LEU A  42
HIS A 156
LEU A 154
LEU A  86
 None
 1.34A 2azqA-5fccA:
undetectable		 2azqA-5fccA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A65_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5fcc HUTD
(Pseudomonas
fluorescens) 		5 / 12 ALA A  57
VAL A  97
ASP A  76
SER A  55
GLY A  58
 None
 1.20A 3a65A-5fccA:
undetectable		 3a65A-5fccA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 5fcc HUTD
(Pseudomonas
fluorescens) 		3 / 3 TYR A  59
ARG A 117
SER A 114
 NA  A 205 (-4.5A)
EDO  A 202 (-3.9A)
None
 1.06A 4khpI-5fccA:
undetectable
4khpJ-5fccA:
undetectable		 4khpI-5fccA:
18.75
4khpJ-5fccA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 5fcc HUTD
(Pseudomonas
fluorescens) 		3 / 3 TYR A  59
ARG A 117
SER A 114
 NA  A 205 (-4.5A)
EDO  A 202 (-3.9A)
None
 1.03A 4lf7I-5fccA:
undetectable
4lf7J-5fccA:
undetectable		 4lf7I-5fccA:
19.80
4lf7J-5fccA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 5fcc HUTD
(Pseudomonas
fluorescens) 		3 / 3 TYR A  59
ARG A 117
SER A 114
 NA  A 205 (-4.5A)
EDO  A 202 (-3.9A)
None
 1.03A 4lf8I-5fccA:
undetectable
4lf8J-5fccA:
undetectable		 4lf8I-5fccA:
19.80
4lf8J-5fccA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)		 5fcc HUTD
(Pseudomonas
fluorescens) 		3 / 3 GLU A  25
ARG A  14
GLN A  67
 None
 0.85A 4rtbA-5fccA:
undetectable		 4rtbA-5fccA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_1
(DIHYDROFOLATE
REDUCTASE)		 5fcc HUTD
(Pseudomonas
fluorescens) 		3 / 3 ASP A  46
ARG A  61
ARG A  41
 None
CL  A 204 (-3.1A)
None
 0.94A 5eajB-5fccA:
undetectable		 5eajB-5fccA:
22.07