SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fd5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZLQ_A_ACTA1507_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	5fd5	FERRIC UPTAKE REGULATION PROTEIN (Rhizobium leguminosarum)	3 / 3	GLN A 114 HIS A 128 ARG A 129	None	1.04A	1zlqA-5fd5A: undetectable	1zlqA-5fd5A: 13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BYO_A_LNLA1216_1 (LIPOPROTEIN LPPX)	5fd5	FERRIC UPTAKE REGULATION PROTEIN (Rhizobium leguminosarum)	4 / 5	LEU A 130 ILE A 110 LEU A 113 ARG A 116	None	0.88A	2byoA-5fd5A: undetectable	2byoA-5fd5A: 21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P4W_B_DSFB319_1 (GLR4197 PROTEIN)	5fd5	FERRIC UPTAKE REGULATION PROTEIN (Rhizobium leguminosarum)	5 / 9	PRO A 37 ILE A 71 VAL A 62 ILE A 29 ILE A 26	None	1.27A	3p4wB-5fd5A: undetectable	3p4wB-5fd5A: 19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RTS_A_SAMA301_0 (DNA ADENINE METHYLASE)	5fd5	FERRIC UPTAKE REGULATION PROTEIN (Rhizobium leguminosarum)	5 / 12	PHE A 76 GLY A 79 ASP A 78 ASP A 75 TYR A 83	None	1.15A	4rtsA-5fd5A: undetectable	4rtsA-5fd5A: 21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_A_ACTA310_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	5fd5	FERRIC UPTAKE REGULATION PROTEIN (Rhizobium leguminosarum)	3 / 3	GLU A 84 HIS A 36 ARG A 82	None	0.64A	5uunA-5fd5A: undetectable	5uunA-5fd5A: 19.38

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ZLQ_A_ACTA1507_0","NICKEL-BINDING PERIPLASMIC PROTEIN","5fd5","FERRIC UPTAKE REGULATION PROTEIN","Rhizobium leguminosarum",3,"GLN A 114;HIS A 128;ARG A 129","None","1.04A","1zlqA-5fd5A:undetectable","1zlqA-5fd5A:13.25"],["2BYO_A_LNLA1216_1","LIPOPROTEIN LPPX","5fd5","FERRIC UPTAKE REGULATION PROTEIN","Rhizobium leguminosarum",4,"LEU A 130;ILE A 110;LEU A 113;ARG A 116","None","0.88A","2byoA-5fd5A:undetectable","2byoA-5fd5A:21.23"],["3P4W_B_DSFB319_1","GLR4197 PROTEIN","5fd5","FERRIC UPTAKE REGULATION PROTEIN","Rhizobium leguminosarum",5,"PRO A  37;ILE A  71;VAL A  62;ILE A  29;ILE A  26","None","1.27A","3p4wB-5fd5A:undetectable","3p4wB-5fd5A:19.09"],["4RTS_A_SAMA301_0","DNA ADENINE METHYLASE","5fd5","FERRIC UPTAKE REGULATION PROTEIN","Rhizobium leguminosarum",5,"PHE A  76;GLY A  79;ASP A  78;ASP A  75;TYR A  83","None","1.15A","4rtsA-5fd5A:undetectable","4rtsA-5fd5A:21.07"],["5UUN_A_ACTA310_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN","5fd5","FERRIC UPTAKE REGULATION PROTEIN","Rhizobium leguminosarum",3,"GLU A  84;HIS A  36;ARG A  82","None","0.64A","5uunA-5fd5A:undetectable","5uunA-5fd5A:19.38"]]