SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fda'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		3 / 3 ALA A  77
VAL A  62
TRP A  75
 None
 0.87A 1av2C-5fdaA:
undetectable
1av2D-5fdaA:
undetectable		 1av2C-5fdaA:
9.24
1av2D-5fdaA:
9.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CD2_A_FOLA307_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
THR A  47
LEU A  55
TYR A 101
THR A 114
 None
 0.52A 1cd2A-5fdaA:
14.0		 1cd2A-5fdaA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DDR_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ALA A   8
THR A  47
SER A  50
LEU A  55
TYR A 101
 None
 0.73A 1ddrA-5fdaA:
19.4		 1ddrA-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DDR_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
 None
 0.54A 1ddrA-5fdaA:
19.4		 1ddrA-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DDR_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
THR A  47
ILE A  51
LEU A  55
ARG A  58
TYR A 101
 None
 1.27A 1ddrA-5fdaA:
19.4		 1ddrA-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DDR_B_MTXB200_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.52A 1ddrB-5fdaA:
19.4		 1ddrB-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DDS_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.51A 1ddsA-5fdaA:
19.7		 1ddsA-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DDS_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
THR A  47
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.13A 1ddsA-5fdaA:
19.7		 1ddsA-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DDS_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
SER A  50
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.49A 1ddsB-5fdaA:
19.8		 1ddsB-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DDS_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
SER A  50
ILE A  51
ARG A  53
LEU A  55
TYR A 101
 None
 0.84A 1ddsB-5fdaA:
19.8		 1ddsB-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DDS_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ILE A   6
SER A  50
LEU A  55
ARG A  58
TYR A 101
 None
 1.20A 1ddsB-5fdaA:
19.8		 1ddsB-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DHF_A_FOLA187_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.51A 1dhfA-5fdaA:
14.3		 1dhfA-5fdaA:
31.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DHF_B_FOLB187_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.49A 1dhfB-5fdaA:
14.4		 1dhfB-5fdaA:
31.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DHF_B_FOLB187_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.06A 1dhfB-5fdaA:
14.4		 1dhfB-5fdaA:
31.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DHI_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ALA A   8
SER A  50
LEU A  55
TYR A 101
THR A 114
 None
 0.73A 1dhiA-5fdaA:
19.5		 1dhiA-5fdaA:
79.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DHI_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.57A 1dhiA-5fdaA:
19.5		 1dhiA-5fdaA:
79.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DHI_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ILE A   6
ILE A  51
ARG A  53
LEU A  55
TYR A 101
 None
 0.93A 1dhiA-5fdaA:
19.5		 1dhiA-5fdaA:
79.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DHI_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 11 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.54A 1dhiB-5fdaA:
19.9		 1dhiB-5fdaA:
79.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DHJ_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.57A 1dhjA-5fdaA:
19.6		 1dhjA-5fdaA:
78.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DHJ_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
SER A  50
LEU A  55
TYR A 101
THR A 114
 None
 0.78A 1dhjA-5fdaA:
19.6		 1dhjA-5fdaA:
78.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DHJ_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
PRO A  56
TYR A 101
THR A 114
 None
 0.70A 1dhjB-5fdaA:
19.8		 1dhjB-5fdaA:
78.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DLS_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
SER A  50
ILE A  51
LEU A  55
TYR A 101
 None
 0.53A 1dlsA-5fdaA:
14.7		 1dlsA-5fdaA:
31.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DLS_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
SER A  50
LEU A  55
ARG A  58
TYR A 101
 None
 1.13A 1dlsA-5fdaA:
14.7		 1dlsA-5fdaA:
31.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DRA_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
 None
 0.60A 1draA-5fdaA:
19.7		 1draA-5fdaA:
79.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DRA_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.55A 1draB-5fdaA:
19.8		 1draB-5fdaA:
79.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DRB_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ALA A   8
SER A  50
LEU A  55
TYR A 101
THR A 114
 None
 0.77A 1drbA-5fdaA:
19.6		 1drbA-5fdaA:
79.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DRB_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.59A 1drbA-5fdaA:
19.6		 1drbA-5fdaA:
79.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DRB_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.59A 1drbB-5fdaA:
19.8		 1drbB-5fdaA:
79.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DRE_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ALA A   8
SER A  50
ILE A  51
LEU A  55
TYR A 101
 None
 0.66A 1dreA-5fdaA:
19.7		 1dreA-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DRF_A_FOLA187_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
SER A  50
ILE A  51
LEU A  55
TYR A 101
 None
 0.61A 1drfA-5fdaA:
14.7		 1drfA-5fdaA:
31.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DYI_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.49A 1dyiA-5fdaA:
19.8		 1dyiA-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DYI_B_FOLB161_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.49A 1dyiB-5fdaA:
19.9		 1dyiB-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DYR_A_TOPA407_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 11 ILE A   6
ALA A   8
ILE A  51
TYR A 101
THR A 114
 None
 0.45A 1dyrA-5fdaA:
14.1		 1dyrA-5fdaA:
31.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J3J_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 10 ILE A   6
ALA A   8
SER A  50
ILE A  51
TYR A 101
THR A 114
 None
 0.58A 1j3jA-5fdaA:
7.1		 1j3jA-5fdaA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J3J_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 9 ALA A   8
SER A  50
ILE A  51
TYR A 101
THR A 114
 None
 0.34A 1j3jB-5fdaA:
14.5		 1j3jB-5fdaA:
20.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JOL_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.54A 1jolA-5fdaA:
19.8		 1jolA-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JOL_B_FFOB361_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
PRO A  56
TYR A 101
THR A 114
 None
 0.62A 1jolB-5fdaA:
19.9		 1jolB-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JOM_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 11 ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.45A 1jomA-5fdaA:
20.5		 1jomA-5fdaA:
80.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_A_FOLA605_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ALA A   8
THR A  47
ILE A  51
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.04A 1qzfA-5fdaA:
14.3		 1qzfA-5fdaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_B_FOLB609_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ALA A   8
THR A  47
ILE A  51
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.04A 1qzfB-5fdaA:
14.3		 1qzfB-5fdaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_C_FOLC613_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ALA A   8
THR A  47
ILE A  51
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.04A 1qzfC-5fdaA:
8.0		 1qzfC-5fdaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_D_FOLD617_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ALA A   8
THR A  47
ILE A  51
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.04A 1qzfD-5fdaA:
14.2		 1qzfD-5fdaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_E_FOLE621_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ALA A   8
THR A  47
ILE A  51
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.05A 1qzfE-5fdaA:
7.2		 1qzfE-5fdaA:
16.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RA2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.53A 1ra2A-5fdaA:
19.8		 1ra2A-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RA3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.57A 1ra3A-5fdaA:
19.9		 1ra3A-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RA8_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.48A 1ra8A-5fdaA:
19.9		 1ra8A-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RA8_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ILE A   6
THR A  47
ILE A  51
ARG A  53
LEU A  55
 None
 0.84A 1ra8A-5fdaA:
19.9		 1ra8A-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RB2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.56A 1rb2A-5fdaA:
19.8		 1rb2A-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RB2_B_FOLB161_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.10A 1rb2B-5fdaA:
20.0		 1rb2B-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RB3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 10 ILE A   6
ALA A   8
ILE A  51
TYR A 101
THR A 114
 None
 0.45A 1rb3A-5fdaA:
19.6		 1rb3A-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RB3_B_MTXB161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
SER A  50
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.53A 1rb3B-5fdaA:
19.7		 1rb3B-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RB3_B_MTXB161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
SER A  50
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.01A 1rb3B-5fdaA:
19.7		 1rb3B-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RD7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.52A 1rd7A-5fdaA:
20.0		 1rd7A-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RD7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.53A 1rd7B-5fdaA:
19.9		 1rd7B-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RE7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
TYR A 101
THR A 114
 None
 0.36A 1re7A-5fdaA:
19.7		 1re7A-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RE7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
PRO A  56
TYR A 101
THR A 114
 None
 0.55A 1re7B-5fdaA:
19.7		 1re7B-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RG7_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ALA A   7
THR A  47
SER A  50
ILE A  51
LEU A  55
 None
 1.13A 1rg7A-5fdaA:
19.9		 1rg7A-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RG7_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ALA A   8
THR A  47
SER A  50
ILE A  51
LEU A  55
TYR A 101
 None
 0.70A 1rg7A-5fdaA:
19.9		 1rg7A-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RH3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ILE A   6
SER A  50
ILE A  51
LEU A  55
TYR A 101
 None
 0.68A 1rh3A-5fdaA:
19.6		 1rh3A-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RH3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ILE A   6
SER A  50
LEU A  55
ARG A  58
TYR A 101
 None
 1.26A 1rh3A-5fdaA:
19.6		 1rh3A-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RX2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.58A 1rx2A-5fdaA:
20.1		 1rx2A-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RX3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ALA A   7
SER A  50
ILE A  51
LEU A  55
ARG A  58
 None
 1.15A 1rx3A-5fdaA:
19.8		 1rx3A-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RX3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
SER A  50
ILE A  51
LEU A  55
TYR A 101
 None
 0.59A 1rx3A-5fdaA:
19.8		 1rx3A-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RX3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
SER A  50
ILE A  51
LEU A  55
ARG A  58
TYR A 101
 None
 1.14A 1rx3A-5fdaA:
19.8		 1rx3A-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RX7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.54A 1rx7A-5fdaA:
20.2		 1rx7A-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RX8_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
PRO A  56
TYR A 101
THR A 114
 None
 0.59A 1rx8A-5fdaA:
20.1		 1rx8A-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TDR_A_MTXA170_1
(TELLUROMETHIONYL
DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
 None
 0.61A 1tdrA-5fdaA:
19.4		 1tdrA-5fdaA:
79.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TDR_B_MTXB170_1
(TELLUROMETHIONYL
DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 10 ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.59A 1tdrB-5fdaA:
19.5		 1tdrB-5fdaA:
79.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1U70_A_MTXA187_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ILE A   6
ALA A   8
LEU A  55
ARG A  58
TYR A 101
 None
 1.23A 1u70A-5fdaA:
14.6		 1u70A-5fdaA:
31.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		3 / 3 ALA A  77
VAL A  62
TRP A  75
 None
 0.85A 1w5uC-5fdaA:
undetectable
1w5uD-5fdaA:
undetectable		 1w5uC-5fdaA:
9.24
1w5uD-5fdaA:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BL9_A_CP6A1240_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
SER A  50
ILE A  51
TYR A 101
THR A 114
 None
 0.53A 2bl9A-5fdaA:
15.1		 2bl9A-5fdaA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BLA_A_CP6A302_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 11 ILE A   6
ALA A   8
SER A  50
ILE A  51
TYR A 101
THR A 114
 None
 0.62A 2blaA-5fdaA:
14.9		 2blaA-5fdaA:
25.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CD2_A_FOLA307_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
THR A  47
LEU A  55
TYR A 101
THR A 114
 None
 0.53A 2cd2A-5fdaA:
14.1		 2cd2A-5fdaA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CD2_A_FOLA307_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
THR A  47
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.15A 2cd2A-5fdaA:
14.1		 2cd2A-5fdaA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2D0K_A_FOLA1161_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.11A 2d0kA-5fdaA:
20.1		 2d0kA-5fdaA:
77.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2D0K_A_FOLA1161_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
PRO A  56
TYR A 101
THR A 114
 None
 0.59A 2d0kA-5fdaA:
20.1		 2d0kA-5fdaA:
77.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2D0K_B_FOLB2161_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.47A 2d0kB-5fdaA:
19.7		 2d0kB-5fdaA:
77.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2D0K_B_FOLB2161_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.07A 2d0kB-5fdaA:
19.7		 2d0kB-5fdaA:
77.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DRC_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
 None
 0.58A 2drcA-5fdaA:
19.6		 2drcA-5fdaA:
79.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DRC_B_MTXB161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.53A 2drcB-5fdaA:
19.8		 2drcB-5fdaA:
79.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_A_MTXA605_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ALA A   8
THR A  47
ILE A  51
LEU A  55
ARG A  58
TYR A 101
 None
 1.05A 2oipA-5fdaA:
14.8		 2oipA-5fdaA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_B_MTXB609_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ALA A   8
THR A  47
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.06A 2oipB-5fdaA:
13.7		 2oipB-5fdaA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_C_MTXC613_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ALA A   8
THR A  47
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.07A 2oipC-5fdaA:
14.4		 2oipC-5fdaA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_D_MTXD617_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ALA A   8
THR A  47
ILE A  51
LEU A  55
ARG A  58
TYR A 101
 None
 1.13A 2oipD-5fdaA:
15.4		 2oipD-5fdaA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_E_MTXE621_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ALA A   8
THR A  47
ILE A  51
LEU A  55
ARG A  58
TYR A 101
 None
 1.15A 2oipE-5fdaA:
14.2		 2oipE-5fdaA:
16.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QK8_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ALA A   8
ILE A  51
LEU A  55
PRO A  56
TYR A 101
 None
 0.82A 2qk8A-5fdaA:
18.0		 2qk8A-5fdaA:
39.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W3A_A_TOPA1190_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 11 ILE A   6
ALA A   8
THR A  47
ILE A  51
TYR A 101
THR A 114
 None
 0.49A 2w3aA-5fdaA:
14.4		 2w3aA-5fdaA:
32.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W3A_B_TOPB1189_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 10 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.56A 2w3aB-5fdaA:
14.5		 2w3aB-5fdaA:
32.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W3B_A_FOLA401_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.44A 2w3bA-5fdaA:
14.2		 2w3bA-5fdaA:
32.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W3B_B_FOLB401_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.49A 2w3bB-5fdaA:
14.2		 2w3bB-5fdaA:
32.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W3M_A_FOLA1188_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.53A 2w3mA-5fdaA:
14.2		 2w3mA-5fdaA:
32.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W3M_B_FOLB1188_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.14A 2w3mB-5fdaA:
14.3		 2w3mB-5fdaA:
32.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W9S_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 11 ILE A   6
ALA A   8
SER A  50
ILE A  51
TYR A 101
THR A 114
 None
 0.68A 2w9sA-5fdaA:
17.7		 2w9sA-5fdaA:
40.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W9S_B_TOPB1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 11 ILE A   6
ALA A   8
SER A  50
ILE A  51
TYR A 101
THR A 114
 None
 0.66A 2w9sB-5fdaA:
17.7		 2w9sB-5fdaA:
40.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W9S_C_TOPC1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 10 ILE A   6
ALA A   8
SER A  50
ILE A  51
TYR A 101
THR A 114
 None
 0.67A 2w9sC-5fdaA:
17.7		 2w9sC-5fdaA:
40.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W9S_D_TOPD1158_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 10 ILE A   6
ALA A   8
SER A  50
TYR A 101
THR A 114
 None
 0.38A 2w9sD-5fdaA:
17.6		 2w9sD-5fdaA:
40.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W9S_E_TOPE1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		4 / 8 ILE A   6
ALA A   8
TYR A 101
THR A 114
 None
 0.26A 2w9sE-5fdaA:
17.6		 2w9sE-5fdaA:
40.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W9S_F_TOPF1159_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 10 ILE A   6
ALA A   8
SER A  50
TYR A 101
THR A 114
 None
 0.39A 2w9sF-5fdaA:
17.6		 2w9sF-5fdaA:
40.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZZA_A_FOLA164_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.71A 2zzaA-5fdaA:
19.0		 2zzaA-5fdaA:
56.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZZA_B_FOLB164_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 11 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.70A 2zzaB-5fdaA:
18.9		 2zzaB-5fdaA:
56.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ALA A   7
THR A  47
SER A  50
LEU A  55
PRO A  56
 None
 1.30A 3cl9A-5fdaA:
13.1		 3cl9A-5fdaA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ALA A   8
THR A  47
SER A  50
LEU A  55
ARG A  58
TYR A 101
 None
 1.19A 3cl9A-5fdaA:
13.1		 3cl9A-5fdaA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ALA A   8
THR A  47
SER A  50
LEU A  55
PRO A  56
TYR A 101
 None
 0.73A 3cl9A-5fdaA:
13.1		 3cl9A-5fdaA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_A_TMQA611_1
(DHFR-TS)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 11 ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.37A 3clbA-5fdaA:
13.1		 3clbA-5fdaA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_B_TMQB612_1
(DHFR-TS)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ALA A   8
THR A  47
SER A  50
ILE A  51
TYR A 101
 None
 0.51A 3clbB-5fdaA:
13.0		 3clbB-5fdaA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_C_TMQC613_1
(DHFR-TS)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.38A 3clbC-5fdaA:
13.3		 3clbC-5fdaA:
18.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAU_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
 None
 0.59A 3dauA-5fdaA:
19.8		 3dauA-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DRC_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
 None
 0.57A 3drcA-5fdaA:
19.7		 3drcA-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DRC_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.51A 3drcB-5fdaA:
19.9		 3drcB-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EIG_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ILE A   6
ALA A   8
LEU A  55
ARG A  58
TYR A 101
 None
 1.19A 3eigA-5fdaA:
14.5		 3eigA-5fdaA:
31.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EIG_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ILE A   6
ALA A   8
SER A  50
LEU A  55
TYR A 101
 None
 0.59A 3eigA-5fdaA:
14.5		 3eigA-5fdaA:
31.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FRB_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 11 ALA A   8
SER A  50
ILE A  51
TYR A 101
THR A 114
 None
 0.62A 3frbX-5fdaA:
17.6		 3frbX-5fdaA:
38.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_C_TMQC613_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 11 ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.36A 3hbbC-5fdaA:
13.5		 3hbbC-5fdaA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_A_MTXA605_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ALA A   8
THR A  47
ILE A  51
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.06A 3hj3A-5fdaA:
15.2		 3hj3A-5fdaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_B_MTXB609_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ALA A   8
THR A  47
ILE A  51
LEU A  55
ARG A  58
TYR A 101
 None
 1.13A 3hj3B-5fdaA:
3.9		 3hj3B-5fdaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_C_MTXC613_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ALA A   8
THR A  47
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.10A 3hj3C-5fdaA:
14.5		 3hj3C-5fdaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_D_MTXD615_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ALA A   8
THR A  47
ILE A  51
LEU A  55
ARG A  58
TYR A 101
 None
 1.23A 3hj3D-5fdaA:
12.3		 3hj3D-5fdaA:
16.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IA4_A_MTXA164_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ALA A   8
SER A  50
ILE A  51
LEU A  55
TYR A 101
 None
 0.88A 3ia4A-5fdaA:
19.0		 3ia4A-5fdaA:
57.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IA4_B_MTXB164_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
SER A  50
ILE A  51
LEU A  55
TYR A 101
 None
 0.88A 3ia4B-5fdaA:
18.8		 3ia4B-5fdaA:
57.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IA4_C_MTXC164_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ALA A   8
SER A  50
ILE A  51
LEU A  55
TYR A 101
 None
 0.86A 3ia4C-5fdaA:
18.9		 3ia4C-5fdaA:
57.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IA4_D_MTXD164_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
SER A  50
ILE A  51
LEU A  55
TYR A 101
 None
 0.86A 3ia4D-5fdaA:
18.8		 3ia4D-5fdaA:
57.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_A_LYAA514_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ALA A   8
THR A  47
ILE A  51
LEU A  55
ARG A  58
TYR A 101
 None
 1.09A 3k2hA-5fdaA:
14.9		 3k2hA-5fdaA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ALA A   8
ILE A  51
LEU A  55
ARG A  58
TYR A 101
 None
 1.17A 3k2hB-5fdaA:
4.8		 3k2hB-5fdaA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		3 / 3 ALA A  77
VAL A  62
TRP A  75
 None
 0.84A 3l8lC-5fdaA:
undetectable
3l8lD-5fdaA:
undetectable		 3l8lC-5fdaA:
9.24
3l8lD-5fdaA:
9.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N0H_A_TOPA187_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 11 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.55A 3n0hA-5fdaA:
14.7		 3n0hA-5fdaA:
31.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QFX_A_CP6A602_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ALA A   8
THR A  47
SER A  50
TYR A 101
THR A 114
 None
 0.40A 3qfxA-5fdaA:
13.6		 3qfxA-5fdaA:
28.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QFX_B_CP6B702_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ALA A   8
THR A  47
SER A  50
TYR A 101
THR A 114
 None
 0.40A 3qfxB-5fdaA:
13.7		 3qfxB-5fdaA:
28.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QG2_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 10 ILE A   6
ALA A   8
SER A  50
ILE A  51
TYR A 101
THR A 114
 None
 0.52A 3qg2A-5fdaA:
14.7		 3qg2A-5fdaA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QG2_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 11 ILE A   6
ALA A   8
SER A  50
ILE A  51
TYR A 101
THR A 114
 None
 0.47A 3qg2B-5fdaA:
14.8		 3qg2B-5fdaA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGT_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 10 ILE A   6
ALA A   8
SER A  50
ILE A  51
TYR A 101
THR A 114
 None
 0.56A 3qgtA-5fdaA:
14.8		 3qgtA-5fdaA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGT_B_CP6B609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 10 ILE A   6
ALA A   8
SER A  50
ILE A  51
TYR A 101
THR A 114
 None
 0.49A 3qgtB-5fdaA:
14.4		 3qgtB-5fdaA:
12.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QL0_A_FOLA160_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.54A 3ql0A-5fdaA:
19.9		 3ql0A-5fdaA:
79.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QL3_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ILE A   6
ALA A   8
ILE A  51
TYR A 101
THR A 114
 None
 0.53A 3ql3A-5fdaA:
20.0		 3ql3A-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3S3V_A_TOPA187_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.54A 3s3vA-5fdaA:
14.6		 3s3vA-5fdaA:
31.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TQ8_A_TOPA2001_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 9 ILE A   6
ALA A   8
SER A  50
ILE A  51
THR A 114
 None
 0.72A 3tq8A-5fdaA:
19.0		 3tq8A-5fdaA:
46.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TQ9_A_MTXA2001_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
SER A  50
ILE A  51
LEU A  55
THR A 114
 None
 0.74A 3tq9A-5fdaA:
18.2		 3tq9A-5fdaA:
46.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TQB_A_FOLA2001_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 11 ALA A   8
THR A  47
ILE A  51
LEU A  55
THR A 114
 None
 0.54A 3tqbA-5fdaA:
17.9		 3tqbA-5fdaA:
46.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UM5_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 10 ILE A   6
THR A  47
SER A  50
ILE A  51
TYR A 101
THR A 114
 None
 0.59A 3um5A-5fdaA:
14.8		 3um5A-5fdaA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UM5_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 10 ILE A   6
THR A  47
SER A  50
ILE A  51
TYR A 101
THR A 114
 None
 0.59A 3um5B-5fdaA:
7.2		 3um5B-5fdaA:
12.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CD2_A_FOLA207_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.12A 4cd2A-5fdaA:
14.3		 4cd2A-5fdaA:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DFR_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ALA A   8
THR A  47
SER A  50
LEU A  55
TYR A 101
 None
 0.80A 4dfrA-5fdaA:
19.5		 4dfrA-5fdaA:
79.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DFR_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
 None
 0.58A 4dfrA-5fdaA:
19.5		 4dfrA-5fdaA:
79.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DFR_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
THR A  47
ILE A  51
ARG A  53
LEU A  55
TYR A 101
 None
 0.87A 4dfrA-5fdaA:
19.5		 4dfrA-5fdaA:
79.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DFR_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 THR A  47
SER A  50
ARG A  53
LEU A  55
TYR A 101
 None
 1.04A 4dfrA-5fdaA:
19.5		 4dfrA-5fdaA:
79.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DFR_B_MTXB162_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.55A 4dfrB-5fdaA:
19.8		 4dfrB-5fdaA:
79.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EJ1_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
 None
 0.50A 4ej1A-5fdaA:
20.8		 4ej1A-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EJ1_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.46A 4ej1B-5fdaA:
20.9		 4ej1B-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FHB_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.53A 4fhbA-5fdaA:
19.8		 4fhbA-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FHB_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
THR A  47
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.15A 4fhbA-5fdaA:
19.8		 4fhbA-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G8Z_X_TOPX301_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 10 ILE A   6
ALA A   8
SER A  50
TYR A 101
THR A 114
 None
 0.72A 4g8zX-5fdaA:
14.1		 4g8zX-5fdaA:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GH8_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
SER A  50
ILE A  51
LEU A  55
TYR A 101
 None
 0.52A 4gh8A-5fdaA:
19.0		 4gh8A-5fdaA:
77.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GH8_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ILE A   6
ALA A   8
SER A  50
ILE A  51
TYR A 101
 None
 0.52A 4gh8B-5fdaA:
18.6		 4gh8B-5fdaA:
77.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I13_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
 None
 0.55A 4i13A-5fdaA:
20.3		 4i13A-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I1N_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 11 ILE A   6
ALA A   8
LEU A  55
TYR A 101
THR A 114
 None
 0.52A 4i1nA-5fdaA:
20.3		 4i1nA-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I1N_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 11 ILE A   6
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.23A 4i1nA-5fdaA:
20.3		 4i1nA-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KEB_B_FOLB202_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.49A 4kebB-5fdaA:
14.1		 4kebB-5fdaA:
31.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFJ_B_FOLB202_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.49A 4kfjB-5fdaA:
14.4		 4kfjB-5fdaA:
31.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KJJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
 None
 0.63A 4kjjA-5fdaA:
18.7		 4kjjA-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KJK_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
 None
 0.56A 4kjkA-5fdaA:
19.6		 4kjkA-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KJL_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ALA A   8
THR A  47
ILE A  51
ARG A  53
LEU A  55
TYR A 101
THR A 114
 None
 1.44A 4kjlA-5fdaA:
19.4		 4kjlA-5fdaA:
79.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KJL_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.58A 4kjlA-5fdaA:
19.4		 4kjlA-5fdaA:
79.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KM0_A_CP6A201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 10 ILE A   6
ALA A   8
THR A  47
TYR A 101
THR A 114
 None
 0.70A 4km0A-5fdaA:
15.3		 4km0A-5fdaA:
32.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KM0_B_CP6B201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ILE A   6
ALA A   8
THR A  47
TYR A 101
THR A 114
 None
 0.64A 4km0B-5fdaA:
15.6		 4km0B-5fdaA:
32.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KM2_A_TOPA202_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ALA A   8
THR A  47
LEU A  55
TYR A 101
THR A 114
 None
 0.62A 4km2A-5fdaA:
15.5		 4km2A-5fdaA:
32.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KM2_A_TOPA202_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ILE A   6
ALA A   8
LEU A  55
TYR A 101
THR A 114
 None
 0.55A 4km2A-5fdaA:
15.5		 4km2A-5fdaA:
32.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_A_MTXA603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ALA A   8
SER A  50
ILE A  51
LEU A  55
ARG A  58
THR A 114
 None
 1.16A 4ky8A-5fdaA:
3.9		 4ky8A-5fdaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_B_MTXB603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ALA A   8
SER A  50
ILE A  51
LEU A  55
ARG A  58
THR A 114
 None
 1.20A 4ky8B-5fdaA:
10.7		 4ky8B-5fdaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_D_MTXD603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ALA A   8
SER A  50
ILE A  51
LEU A  55
ARG A  58
THR A 114
 None
 1.20A 4ky8D-5fdaA:
4.8		 4ky8D-5fdaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_E_MTXE603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ALA A   8
SER A  50
ILE A  51
LEU A  55
ARG A  58
THR A 114
 None
 1.21A 4ky8E-5fdaA:
4.3		 4ky8E-5fdaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 11 ALA A   8
THR A  47
LEU A  55
ARG A  58
THR A 114
 None
 1.17A 4kyaA-5fdaA:
14.8		 4kyaA-5fdaA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_E_FOLE703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 11 ALA A   8
THR A  47
LEU A  55
ARG A  58
THR A 114
 None
 1.16A 4kyaE-5fdaA:
14.7		 4kyaE-5fdaA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_G_FOLG703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 11 ALA A   8
THR A  47
LEU A  55
ARG A  58
THR A 114
 None
 1.17A 4kyaG-5fdaA:
14.7		 4kyaG-5fdaA:
15.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2X_C_TMQC202_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ILE A   6
ALA A   8
LEU A  55
TYR A 101
THR A 114
 None
 0.64A 4m2xC-5fdaA:
7.7		 4m2xC-5fdaA:
34.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.44A 4m6kA-5fdaA:
14.7		 4m6kA-5fdaA:
32.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NX6_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
 None
 0.56A 4nx6A-5fdaA:
20.0		 4nx6A-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NX7_A_FOLA202_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
 None
 0.62A 4nx7A-5fdaA:
20.0		 4nx7A-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P3Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
PRO A  56
TYR A 101
 None
 0.68A 4p3qA-5fdaA:
20.1		 4p3qA-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P3R_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
 None
 0.63A 4p3rA-5fdaA:
19.9		 4p3rA-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P66_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 11 ILE A   6
ALA A   8
LEU A  55
TYR A 101
THR A 114
 None
 0.51A 4p66A-5fdaA:
20.1		 4p66A-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P68_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 11 ILE A   6
SER A  50
ILE A  51
ARG A  58
TYR A 101
THR A 114
 None
 1.15A 4p68A-5fdaA:
20.0		 4p68A-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PSS_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
 None
 0.62A 4pssA-5fdaA:
undetectable		 4pssA-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PST_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.62A 4pstA-5fdaA:
undetectable		 4pstA-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PSY_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.62A 4psyA-5fdaA:
20.2		 4psyA-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PTH_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.57A 4pthA-5fdaA:
19.9		 4pthA-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PTJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
TYR A 101
THR A 114
 None
 0.49A 4ptjA-5fdaA:
19.8		 4ptjA-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PTJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
THR A  47
ILE A  51
ARG A  58
TYR A 101
THR A 114
 None
 1.17A 4ptjA-5fdaA:
19.8		 4ptjA-5fdaA:
80.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_A_MTXA604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ALA A   8
ILE A  51
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.14A 4q0dA-5fdaA:
15.2		 4q0dA-5fdaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_B_MTXB604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ALA A   8
ILE A  51
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.14A 4q0dB-5fdaA:
15.1		 4q0dB-5fdaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_C_MTXC604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ALA A   8
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.16A 4q0dC-5fdaA:
15.1		 4q0dC-5fdaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_C_MTXC604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ALA A   8
SER A  50
ARG A  58
TYR A 101
THR A 114
 None
 1.26A 4q0dC-5fdaA:
15.1		 4q0dC-5fdaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_D_MTXD604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ALA A   8
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.16A 4q0dD-5fdaA:
15.2		 4q0dD-5fdaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_D_MTXD604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ALA A   8
SER A  50
ARG A  58
TYR A 101
THR A 114
 None
 1.26A 4q0dD-5fdaA:
15.2		 4q0dD-5fdaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_E_MTXE604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ALA A   8
ILE A  51
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.14A 4q0dE-5fdaA:
15.2		 4q0dE-5fdaA:
16.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QI9_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.48A 4qi9A-5fdaA:
20.1		 4qi9A-5fdaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QI9_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
SER A  50
LEU A  55
TYR A 101
THR A 114
 None
 0.66A 4qi9A-5fdaA:
20.1		 4qi9A-5fdaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QI9_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ILE A   6
ILE A  51
ARG A  53
LEU A  55
TYR A 101
 None
 0.92A 4qi9A-5fdaA:
20.1		 4qi9A-5fdaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QI9_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ILE A   6
SER A  50
ARG A  53
LEU A  55
TYR A 101
 None
 1.01A 4qi9A-5fdaA:
20.1		 4qi9A-5fdaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QI9_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.47A 4qi9B-5fdaA:
20.8		 4qi9B-5fdaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QI9_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
SER A  50
LEU A  55
TYR A 101
THR A 114
 None
 0.66A 4qi9B-5fdaA:
20.8		 4qi9B-5fdaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QI9_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ILE A   6
ILE A  51
ARG A  53
LEU A  55
TYR A 101
 None
 0.93A 4qi9B-5fdaA:
20.8		 4qi9B-5fdaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QI9_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ILE A   6
SER A  50
ARG A  53
LEU A  55
TYR A 101
 None
 1.04A 4qi9B-5fdaA:
20.8		 4qi9B-5fdaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QI9_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
SER A  50
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.22A 4qi9B-5fdaA:
20.8		 4qi9B-5fdaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QI9_C_MTXC201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 11 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.46A 4qi9C-5fdaA:
20.0		 4qi9C-5fdaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QI9_C_MTXC201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 11 ILE A   6
ALA A   8
SER A  50
LEU A  55
TYR A 101
THR A 114
 None
 0.67A 4qi9C-5fdaA:
20.0		 4qi9C-5fdaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QLE_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.55A 4qleA-5fdaA:
19.9		 4qleA-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QLE_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 11 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.54A 4qleB-5fdaA:
20.0		 4qleB-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QLE_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 11 ILE A   6
ALA A   8
SER A  50
LEU A  55
TYR A 101
THR A 114
 None
 0.72A 4qleB-5fdaA:
20.0		 4qleB-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QLE_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 11 ILE A   6
SER A  50
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.19A 4qleB-5fdaA:
20.0		 4qleB-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QLF_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 11 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.51A 4qlfA-5fdaA:
18.2		 4qlfA-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QLF_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 11 ILE A   6
ALA A   8
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.10A 4qlfA-5fdaA:
18.2		 4qlfA-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QLG_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.57A 4qlgA-5fdaA:
20.0		 4qlgA-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QLG_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.48A 4qlgB-5fdaA:
19.6		 4qlgB-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QLG_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
THR A  47
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.09A 4qlgB-5fdaA:
19.6		 4qlgB-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RGC_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.57A 4rgcA-5fdaA:
20.0		 4rgcA-5fdaA:
80.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5F_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.49A 4x5fA-5fdaA:
19.8		 4x5fA-5fdaA:
79.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5F_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
THR A  47
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.12A 4x5fA-5fdaA:
19.8		 4x5fA-5fdaA:
79.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5F_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.49A 4x5fB-5fdaA:
20.1		 4x5fB-5fdaA:
79.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5F_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
THR A  47
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.12A 4x5fB-5fdaA:
20.1		 4x5fB-5fdaA:
79.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5G_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.54A 4x5gA-5fdaA:
19.9		 4x5gA-5fdaA:
79.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5G_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.53A 4x5gB-5fdaA:
20.3		 4x5gB-5fdaA:
79.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5G_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
THR A  47
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.14A 4x5gB-5fdaA:
20.3		 4x5gB-5fdaA:
79.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5H_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.56A 4x5hA-5fdaA:
20.0		 4x5hA-5fdaA:
79.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5I_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.54A 4x5iA-5fdaA:
19.9		 4x5iA-5fdaA:
79.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
TYR A 101
THR A 114
 None
 0.44A 4x5jA-5fdaA:
20.2		 4x5jA-5fdaA:
79.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E8Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
TYR A 101
THR A 114
 None
 0.42A 5e8qA-5fdaA:
19.8		 5e8qA-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E8Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ILE A   6
THR A  47
ILE A  51
ARG A  53
TYR A 101
 None
 0.72A 5e8qA-5fdaA:
19.8		 5e8qA-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E8Q_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.52A 5e8qB-5fdaA:
19.7		 5e8qB-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EAJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.54A 5eajA-5fdaA:
19.7		 5eajA-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EAJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
THR A  47
ILE A  51
ARG A  53
LEU A  55
TYR A 101
 None
 0.80A 5eajA-5fdaA:
19.7		 5eajA-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EAJ_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ALA A   7
THR A  47
ILE A  51
LEU A  55
PRO A  56
 None
 1.10A 5eajB-5fdaA:
19.7		 5eajB-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EAJ_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		8 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
PRO A  56
TYR A 101
THR A 114
 None
 0.65A 5eajB-5fdaA:
19.7		 5eajB-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HI6_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.44A 5hi6A-5fdaA:
20.7		 5hi6A-5fdaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HI6_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
SER A  50
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.10A 5hi6A-5fdaA:
20.7		 5hi6A-5fdaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HI6_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
SER A  50
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.79A 5hi6B-5fdaA:
20.4		 5hi6B-5fdaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HI6_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 12 ILE A   6
SER A  50
ILE A  51
ARG A  53
LEU A  55
 None
 0.99A 5hi6B-5fdaA:
20.4		 5hi6B-5fdaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HI6_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
SER A  50
LEU A  55
ARG A  58
TYR A 101
THR A 114
 None
 1.16A 5hi6B-5fdaA:
20.4		 5hi6B-5fdaA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_1
(PAVINE
N-METHYLTRANSFERASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		4 / 5 PHE A 154
SER A 139
ASN A 148
ASP A 145
 None
 1.29A 5kpcA-5fdaA:
undetectable		 5kpcA-5fdaA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUK_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 10 VAL A  92
ILE A  61
VAL A 100
PHE A 104
ALA A 108
 None
 1.16A 5nukA-5fdaA:
undetectable		 5nukA-5fdaA:
16.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UIH_A_8CVA201_1
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		4 / 8 ILE A   6
ALA A   8
TYR A 101
THR A 114
 None
 0.25A 5uihA-5fdaA:
20.7		 5uihA-5fdaA:
49.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UJX_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.58A 5ujxA-5fdaA:
19.8		 5ujxA-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UJX_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
THR A  47
ILE A  51
ARG A  53
LEU A  55
TYR A 101
 None
 0.79A 5ujxA-5fdaA:
19.8		 5ujxA-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UJX_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.55A 5ujxB-5fdaA:
19.7		 5ujxB-5fdaA:
80.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z6F_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
TYR A 101
THR A 114
 None
 0.50A 5z6fA-5fdaA:
20.1		 5z6fA-5fdaA:
79.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z6F_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		6 / 12 ILE A   6
THR A  47
ILE A  51
ARG A  58
TYR A 101
THR A 114
 None
 1.16A 5z6fA-5fdaA:
20.1		 5z6fA-5fdaA:
79.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z6J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.59A 5z6jA-5fdaA:
20.2		 5z6jA-5fdaA:
79.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.62A 5z6kA-5fdaA:
20.2		 5z6kA-5fdaA:
79.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z6M_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		5 / 11 ILE A   6
ALA A   8
LEU A  55
TYR A 101
THR A 114
 None
 0.48A 5z6mA-5fdaA:
20.4		 5z6mA-5fdaA:
79.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
7DFR_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 5fda DIHYDROFOLATE
REDUCTASE
(Yersinia
pestis) 		7 / 12 ILE A   6
ALA A   8
THR A  47
ILE A  51
LEU A  55
TYR A 101
THR A 114
 None
 0.58A 7dfrA-5fdaA:
19.6		 7dfrA-5fdaA:
80.00