SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fdk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ADS_A_IMNA2_2 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	5fdk	HOLLIDAY JUNCTION RESOLVASE RECU (Bacillus subtilis)	4 / 6	ILE A 138 ILE A 133 TYR A 197 LEU A 172	None	1.10A	3adsA-5fdkA: undetectable	3adsA-5fdkA: 20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W97_C_CHDC306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5fdk	HOLLIDAY JUNCTION RESOLVASE RECU (Bacillus subtilis)	4 / 6	LYS A 151 LEU A 152 PHE A 135 PHE A 111	None	1.09A	5w97C-5fdkA: undetectable 5w97J-5fdkA: undetectable	5w97C-5fdkA: 21.58 5w97J-5fdkA: 17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MN5_E_LLLE301_0 (AMINOGLYCOSIDE N(3)-ACETYLTRANSFERA SE, AAC(3)-IVA)	5fdk	HOLLIDAY JUNCTION RESOLVASE RECU (Bacillus subtilis)	4 / 7	ASP A 131 TYR A 197 GLU A 148 ASP A 150	None	1.37A	6mn5E-5fdkA: undetectable	6mn5E-5fdkA: 16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MN5_F_LLLF301_0 (AMINOGLYCOSIDE N(3)-ACETYLTRANSFERA SE, AAC(3)-IVA)	5fdk	HOLLIDAY JUNCTION RESOLVASE RECU (Bacillus subtilis)	4 / 5	ASP A 131 TYR A 197 GLU A 148 ASP A 150	None	1.21A	6mn5F-5fdkA: 0.0	6mn5F-5fdkA: 16.58

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3ADS_A_IMNA2_2","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","5fdk","HOLLIDAY JUNCTION RESOLVASE RECU","Bacillus subtilis",4,"ILE A 138;ILE A 133;TYR A 197;LEU A 172","None","1.10A","3adsA-5fdkA:undetectable","3adsA-5fdkA:20.69"],["5W97_C_CHDC306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5fdk","HOLLIDAY JUNCTION RESOLVASE RECU","Bacillus subtilis",4,"LYS A 151;LEU A 152;PHE A 135;PHE A 111","None","1.09A","5w97C-5fdkA:undetectable;5w97J-5fdkA:undetectable","5w97C-5fdkA:21.58;5w97J-5fdkA:17.60"],["6MN5_E_LLLE301_0","AMINOGLYCOSIDE N(3)-ACETYLTRANSFERASE, AAC(3)-IVA","5fdk","HOLLIDAY JUNCTION RESOLVASE RECU","Bacillus subtilis",4,"ASP A 131;TYR A 197;GLU A 148;ASP A 150","None","1.37A","6mn5E-5fdkA:undetectable","6mn5E-5fdkA:16.58"],["6MN5_F_LLLF301_0","AMINOGLYCOSIDE N(3)-ACETYLTRANSFERASE, AAC(3)-IVA","5fdk","HOLLIDAY JUNCTION RESOLVASE RECU","Bacillus subtilis",4,"ASP A 131;TYR A 197;GLU A 148;ASP A 150","None","1.21A","6mn5F-5fdkA:0.0","6mn5F-5fdkA:16.58"]]