SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fdn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 5 LEU A 840
SER A  85
LEU A  86
GLY A  80
 None
 1.03A 1a4lB-5fdnA:
4.6		 1a4lB-5fdnA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F9G_A_ASCA950_0
(HYALURONATE LYASE)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 7 ARG A 690
ASN A 966
ARG A 891
ARG A 887
 None
ASP  A1001 (-3.0A)
ASP  A1001 (-2.9A)
ASP  A1001 ( 3.8A)
 1.21A 1f9gA-5fdnA:
2.7		 1f9gA-5fdnA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 8 PHE A 143
ILE A 139
LEU A 161
VAL A 259
 None
 0.80A 1fslB-5fdnA:
1.7		 1fslB-5fdnA:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_A_MTXA1278_1
(PTERIDINE REDUCTASE
2)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		5 / 10 ARG A  71
SER A  64
LEU A 102
LEU A 888
THR A 967
 None
 1.35A 1mxfA-5fdnA:
undetectable		 1mxfA-5fdnA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_B_MTXB2278_1
(PTERIDINE REDUCTASE
2)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		5 / 11 ARG A  71
SER A  64
LEU A 102
LEU A 888
THR A 967
 None
 1.34A 1mxfB-5fdnA:
1.1		 1mxfB-5fdnA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NR6_A_DIFA501_1
(CYTOCHROME P450 2C5)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		5 / 9 LEU A 378
GLY A 372
LEU A 432
LEU A 412
PHE A 435
 None
 1.16A 1nr6A-5fdnA:
undetectable		 1nr6A-5fdnA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_A_RBFA100_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		5 / 11 SER A  85
CYH A 901
THR A 952
THR A 956
ILE A  94
 None
 1.16A 1pkvA-5fdnA:
undetectable
1pkvB-5fdnA:
undetectable		 1pkvA-5fdnA:
6.41
1pkvB-5fdnA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_B_RBFB101_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		5 / 11 ILE A  94
SER A  85
CYH A 901
THR A 952
THR A 956
 None
 1.14A 1pkvA-5fdnA:
undetectable
1pkvB-5fdnA:
undetectable		 1pkvA-5fdnA:
6.41
1pkvB-5fdnA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 5 ASP A 849
GLU A 848
LEU A 741
LEU A 850
 None
 1.07A 1u18B-5fdnA:
undetectable		 1u18B-5fdnA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		3 / 3 LYS A 616
ASP A 802
ASP A 715
 None
 0.96A 2br4D-5fdnA:
undetectable		 2br4D-5fdnA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 5 ARG A 666
MET A 634
THR A 633
LEU A 632
 None
 1.15A 2eimJ-5fdnA:
undetectable		 2eimJ-5fdnA:
4.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 5 ARG A 557
MET A 634
THR A 633
LEU A 632
 None
 1.42A 2eimW-5fdnA:
undetectable		 2eimW-5fdnA:
4.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 5 ARG A 666
MET A 634
THR A 633
LEU A 632
 None
 1.14A 2eimW-5fdnA:
undetectable		 2eimW-5fdnA:
4.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		3 / 3 ASP A 567
ASP A 600
ASP A 539
 None
 0.71A 2igtA-5fdnA:
undetectable		 2igtA-5fdnA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_D_MTXD617_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		5 / 12 ALA A 307
LEU A 521
SER A 523
ILE A 451
LEU A 556
 None
 1.14A 2oipD-5fdnA:
undetectable		 2oipD-5fdnA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1501_1
(CYTOCHROME P450 3A4)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		5 / 10 PHE A 635
ASP A 167
SER A 655
LEU A 170
GLY A 637
 None
 1.28A 2v0mA-5fdnA:
0.0		 2v0mA-5fdnA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		5 / 12 SER A 599
GLY A 968
GLY A 671
THR A 171
LEU A 170
 None
 1.00A 2wa2B-5fdnA:
undetectable		 2wa2B-5fdnA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_B_CL9B401_2
(DEOXYCYTIDINE KINASE)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 4 ARG A 188
ASP A 191
LEU A 107
ARG A 180
 None
 0.89A 2ziaB-5fdnA:
undetectable		 2ziaB-5fdnA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 5 ARG A 666
MET A 634
THR A 633
LEU A 632
 None
 1.22A 3ag1J-5fdnA:
undetectable		 3ag1J-5fdnA:
4.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 5 ARG A 666
MET A 634
THR A 633
LEU A 632
 None
 1.19A 3ag2J-5fdnA:
undetectable		 3ag2J-5fdnA:
4.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 5 ARG A 666
MET A 634
THR A 633
LEU A 632
 None
 1.16A 3ag4J-5fdnA:
undetectable		 3ag4J-5fdnA:
4.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 6 THR A 781
GLN A 902
LEU A 845
LEU A 906
 None
 0.88A 3bgdA-5fdnA:
undetectable		 3bgdA-5fdnA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 8 PRO A 500
LEU A 512
ASP A 513
LYS A 516
 None
 1.10A 3lsfH-5fdnA:
undetectable		 3lsfH-5fdnA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		5 / 12 LEU A 521
ARG A 301
GLY A 287
SER A 283
LEU A 305
 None
 1.38A 3okxA-5fdnA:
undetectable		 3okxA-5fdnA:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 5 HIS A 650
THR A 692
GLU A 697
ASP A 149
 None
 1.20A 3tm4A-5fdnA:
undetectable		 3tm4A-5fdnA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 5 HIS A 650
THR A 692
GLU A 697
ASP A 149
 None
 1.17A 3tm4B-5fdnA:
undetectable		 3tm4B-5fdnA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9W_A_VGHA1158_1
(7,8-DIHYDRO-8-OXOGUA
NINE TRIPHOSPHATASE)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		5 / 12 TYR A 894
LEU A 898
PHE A  41
MET A 101
PHE A 221
 None
 1.36A 4c9wA-5fdnA:
undetectable		 4c9wA-5fdnA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 5 LEU A 785
ILE A 766
ALA A 777
PHE A 739
 None
 1.09A 4dc3B-5fdnA:
undetectable		 4dc3B-5fdnA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_A_TEPA402_1
(PYRIDOXAL KINASE)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 5 GLY A 527
THR A 633
VAL A 559
ASP A 450
 None
 1.13A 4eohA-5fdnA:
undetectable		 4eohA-5fdnA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_C_D16C301_1
(THYMIDYLATE SYNTHASE)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		5 / 11 GLU A 549
ASP A 501
LEU A 502
GLY A 499
PHE A 498
 None
 1.44A 4foxC-5fdnA:
undetectable		 4foxC-5fdnA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		5 / 12 GLY A 968
LEU A 964
PHE A 776
ILE A 775
VAL A 787
 None
 1.08A 4fr0A-5fdnA:
undetectable		 4fr0A-5fdnA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KSZ_A_CYSA620_0
(LACTOPEROXIDASE)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		3 / 3 ARG A 271
GLU A 270
PHE A 158
 None
 1.02A 4kszA-5fdnA:
0.6		 4kszA-5fdnA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_2
(NEURAMINIDASE)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 5 LEU A 840
ASP A 834
ARG A 782
ILE A 895
 None
 1.11A 4mwrA-5fdnA:
undetectable		 4mwrA-5fdnA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 5 LEU A 683
ARG A 118
ARG A 690
THR A 247
 None
 1.42A 4p3qA-5fdnA:
undetectable		 4p3qA-5fdnA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_A_HQEA503_1
(CATALASE)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		5 / 9 ILE A 319
PRO A 411
PHE A 402
LEU A 378
TYR A 315
 None
 1.39A 4qopA-5fdnA:
undetectable		 4qopA-5fdnA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_B_HQEB503_1
(CATALASE)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		5 / 9 ILE A 319
PRO A 411
PHE A 402
LEU A 378
TYR A 315
 None
 1.40A 4qopB-5fdnA:
undetectable		 4qopB-5fdnA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_B_ADNB301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		5 / 9 LEU A  79
GLY A  80
LEU A 898
VAL A 900
THR A 897
 None
 1.21A 4x3mB-5fdnA:
undetectable		 4x3mB-5fdnA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		3 / 3 TRP A 583
ARG A 587
LEU A 578
 None
 0.68A 5dbyA-5fdnA:
undetectable		 5dbyA-5fdnA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		5 / 10 ALA A 694
GLU A 697
LEU A 654
ARG A 145
GLY A 647
 None
None
None
None
FLC  A1002 (-3.3A)
 1.30A 5dxbA-5fdnA:
2.9		 5dxbA-5fdnA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_V_BEZV801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 4 ILE A 518
ILE A 451
ARG A 289
LEU A 521
 None
 0.92A 5dzkh-5fdnA:
undetectable
5dzkn-5fdnA:
undetectable
5dzkv-5fdnA:
undetectable		 5dzkh-5fdnA:
11.74
5dzkn-5fdnA:
11.74
5dzkv-5fdnA:
3.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_2
(ESTROGEN RECEPTOR)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 6 LEU A 419
LEU A 436
LEU A 433
LEU A 322
 None
 0.72A 5gs4A-5fdnA:
3.1		 5gs4A-5fdnA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IM2_A_BEZA401_0
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		5 / 12 PHE A 255
VAL A 166
ILE A 139
LEU A 256
GLN A 164
 None
 1.12A 5im2A-5fdnA:
undetectable		 5im2A-5fdnA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		5 / 12 LEU A 714
PHE A 818
TYR A 813
ILE A 823
LEU A 806
 None
 1.28A 5ljcA-5fdnA:
undetectable		 5ljcA-5fdnA:
9.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_2
(CYTOCHROME P450 3A5)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 5 ARG A 858
PHE A 739
LEU A 785
LEU A 845
 None
 1.10A 5veuH-5fdnA:
1.5		 5veuH-5fdnA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		5 / 12 GLN A 965
ALA A 962
GLU A 110
ILE A 674
VAL A 178
 ASP  A1001 (-3.7A)
None
None
None
None
 1.22A 5vlmG-5fdnA:
2.2		 5vlmG-5fdnA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 5 ARG A 666
MET A 634
THR A 633
LEU A 632
 None
 1.19A 5w97J-5fdnA:
undetectable		 5w97J-5fdnA:
4.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 5 ARG A 666
MET A 634
THR A 633
LEU A 632
 None
 1.12A 5wauJ-5fdnA:
undetectable		 5wauJ-5fdnA:
4.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		5 / 9 ALA A 694
GLU A 697
LEU A 654
ARG A 145
GLY A 647
 None
None
None
None
FLC  A1002 (-3.3A)
 1.34A 5wgqA-5fdnA:
3.7		 5wgqA-5fdnA:
6.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 5 ARG A 666
MET A 634
THR A 633
LEU A 632
 None
 1.18A 5x19J-5fdnA:
undetectable		 5x19J-5fdnA:
4.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 5 ARG A 666
MET A 634
THR A 633
LEU A 632
 None
 1.28A 5x1bJ-5fdnA:
undetectable		 5x1bJ-5fdnA:
4.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 5 ARG A 666
MET A 634
THR A 633
LEU A 632
 None
 1.32A 5x1bW-5fdnA:
undetectable		 5x1bW-5fdnA:
4.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 5 ARG A 666
MET A 634
THR A 633
LEU A 632
 None
 1.24A 5x1fW-5fdnA:
undetectable		 5x1fW-5fdnA:
4.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		5 / 12 ILE A 279
LEU A 683
THR A 687
LEU A 688
PHE A 678
 None
 1.24A 5xxiA-5fdnA:
undetectable		 5xxiA-5fdnA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 5 ARG A 666
MET A 634
THR A 633
LEU A 632
 None
 1.09A 5z86J-5fdnA:
undetectable		 5z86J-5fdnA:
4.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYB_A_KKKA508_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		5 / 12 PHE A 735
PHE A 730
ALA A 838
ILE A 775
LEU A 785
 None
 1.21A 6aybA-5fdnA:
2.6		 6aybA-5fdnA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3
(Arabidopsis
thaliana) 		4 / 5 ARG A 666
MET A 634
THR A 633
LEU A 632
 None
 1.32A 6nknJ-5fdnA:
undetectable		 6nknJ-5fdnA:
4.26