SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5feb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_A_BHSA1610_1
(NITRIC OXIDE
SYNTHASE)		 5feb SODIUM CHANNEL
SUBUNIT BETA-2
(Homo
sapiens) 		4 / 8 VAL A 146
ARG A  98
ALA A  46
GLU A 122
 None
 1.07A 1dmiA-5febA:
undetectable
1dmiB-5febA:
undetectable		 1dmiA-5febA:
13.53
1dmiB-5febA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5feb SODIUM CHANNEL
SUBUNIT BETA-2
(Homo
sapiens) 		3 / 3 GLN A  82
THR A  68
ASN A  66
 None
 0.69A 3v4tE-5febA:
undetectable		 3v4tE-5febA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5feb SODIUM CHANNEL
SUBUNIT BETA-2
(Homo
sapiens) 		4 / 5 PRO A  35
HIS A 139
LEU A  81
TYR A  69
 None
 1.12A 5igjA-5febA:
undetectable		 5igjA-5febA:
17.47