SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fej'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_A_DESA600_1
(ESTROGEN RECEPTOR
ALPHA)		 5fej COPM
(Synechocystis
sp.
PCC
6803) 		5 / 12 MET A  63
LEU A 128
ALA A 130
HIS A 148
MET A 145
 None
None
None
CU1  A 202 (-2.8A)
CU1  A 202 (-3.3A)
 1.19A 3erdA-5fejA:
undetectable		 3erdA-5fejA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 5fej COPM
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A  56
HIS A  57
MET A  53
 CU1  A 201 (-2.9A)
CU1  A 201 (-2.9A)
CU1  A 201 (-3.0A)
 0.90A 3mihA-5fejA:
undetectable		 3mihA-5fejA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 5fej COPM
(Synechocystis
sp.
PCC
6803) 		3 / 3 HIS A 148
HIS A 149
MET A 145
 CU1  A 202 (-2.8A)
CU1  A 202 (-2.8A)
CU1  A 202 (-3.3A)
 0.85A 3mihA-5fejA:
undetectable		 3mihA-5fejA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_A_DESA601_1
(ESTROGEN RECEPTOR)		 5fej COPM
(Synechocystis
sp.
PCC
6803) 		5 / 12 MET A  63
LEU A 128
ALA A 130
HIS A 148
MET A 145
 None
None
None
CU1  A 202 (-2.8A)
CU1  A 202 (-3.3A)
 1.13A 4zn7A-5fejA:
undetectable		 4zn7A-5fejA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_B_DESB600_1
(ESTROGEN RECEPTOR)		 5fej COPM
(Synechocystis
sp.
PCC
6803) 		5 / 11 MET A  63
LEU A 128
ALA A 130
HIS A 148
MET A 145
 None
None
None
CU1  A 202 (-2.8A)
CU1  A 202 (-3.3A)
 1.13A 4zn7B-5fejA:
undetectable		 4zn7B-5fejA:
19.78