SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5feu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_A_NCAA506_0
(NAD-DEPENDENT
DEACETYLASE 2)		 5feu NOROXOMARITIDINE/NOR
CRAUGSODINE
REDUCTASE
(Narcissus
pseudonarcissus) 		4 / 6 SER A 152
PHE A 100
ASN A 105
ILE A 106
 None
 1.00A 1yc2A-5feuA:
4.4		 1yc2A-5feuA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 5feu NOROXOMARITIDINE/NOR
CRAUGSODINE
REDUCTASE
(Narcissus
pseudonarcissus) 		4 / 8 ASP A 126
LYS A 117
GLY A 171
TYR A 175
 None
None
None
NAP  A 301 (-4.6A)
 1.05A 2aouA-5feuA:
7.1		 2aouA-5feuA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5feu NOROXOMARITIDINE/NOR
CRAUGSODINE
REDUCTASE
(Narcissus
pseudonarcissus) 		5 / 12 GLY A  32
ARG A  57
ASP A  82
ASN A 110
ALA A 111
 NAP  A 301 (-3.3A)
NAP  A 301 (-3.5A)
NAP  A 301 (-3.7A)
NAP  A 301 (-3.3A)
NAP  A 301 ( 3.8A)
 1.02A 2bm9E-5feuA:
5.7		 2bm9E-5feuA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5feu NOROXOMARITIDINE/NOR
CRAUGSODINE
REDUCTASE
(Narcissus
pseudonarcissus) 		5 / 12 GLY A  32
ARG A  57
ASP A  82
SER A  84
ALA A 111
 NAP  A 301 (-3.3A)
NAP  A 301 (-3.5A)
NAP  A 301 (-3.7A)
NAP  A 301 ( 4.6A)
NAP  A 301 ( 3.8A)
 0.75A 2br4C-5feuA:
5.8		 2br4C-5feuA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 5feu NOROXOMARITIDINE/NOR
CRAUGSODINE
REDUCTASE
(Narcissus
pseudonarcissus) 		5 / 12 THR A 210
ASP A  82
VAL A  83
VAL A 133
TYR A 175
 NAP  A 301 (-3.1A)
NAP  A 301 (-3.7A)
NAP  A 301 (-3.5A)
None
NAP  A 301 (-4.6A)
 1.38A 2g72A-5feuA:
6.7		 2g72A-5feuA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5feu NOROXOMARITIDINE/NOR
CRAUGSODINE
REDUCTASE
(Narcissus
pseudonarcissus) 		5 / 10 THR A 268
SER A 176
GLY A 206
ALA A 204
GLN A 166
 None
 1.44A 2x2iB-5feuA:
undetectable		 2x2iB-5feuA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5feu NOROXOMARITIDINE/NOR
CRAUGSODINE
REDUCTASE
(Narcissus
pseudonarcissus) 		5 / 12 GLY A  32
ALA A  40
ASP A  82
VAL A  83
VAL A 133
 NAP  A 301 (-3.3A)
None
NAP  A 301 (-3.7A)
NAP  A 301 (-3.5A)
None
 1.11A 3dmfA-5feuA:
7.1		 3dmfA-5feuA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 5feu NOROXOMARITIDINE/NOR
CRAUGSODINE
REDUCTASE
(Narcissus
pseudonarcissus) 		3 / 3 PRO A 251
SER A  22
ASN A 105
 None
 0.93A 3lslG-5feuA:
0.5		 3lslG-5feuA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 5feu NOROXOMARITIDINE/NOR
CRAUGSODINE
REDUCTASE
(Narcissus
pseudonarcissus) 		5 / 12 GLY A  33
ALA A 242
ALA A 245
LEU A  29
LEU A  45
 NAP  A 301 ( 4.6A)
None
None
None
None
 1.18A 3mteA-5feuA:
4.9		 3mteA-5feuA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_ACTB1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 5feu NOROXOMARITIDINE/NOR
CRAUGSODINE
REDUCTASE
(Narcissus
pseudonarcissus) 		4 / 7 ILE A 235
ARG A 234
GLY A 233
VAL A 230
 None
 0.91A 4a3uB-5feuA:
3.1		 4a3uB-5feuA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 5feu NOROXOMARITIDINE/NOR
CRAUGSODINE
REDUCTASE
(Narcissus
pseudonarcissus) 		5 / 11 ILE A  41
ILE A  37
GLY A  36
VAL A 263
GLY A 236
 None
NAP  A 301 (-3.8A)
NAP  A 301 ( 3.7A)
None
None
 0.93A 4ac9B-5feuA:
6.0
4ac9C-5feuA:
5.9		 4ac9B-5feuA:
21.11
4ac9C-5feuA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_0
(WBDD)		 5feu NOROXOMARITIDINE/NOR
CRAUGSODINE
REDUCTASE
(Narcissus
pseudonarcissus) 		5 / 12 ILE A 261
ILE A 203
VAL A 158
HIS A 159
ILE A 160
 None
None
None
None
NAP  A 301 (-4.3A)
 0.98A 4ax8A-5feuA:
7.5		 4ax8A-5feuA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5feu NOROXOMARITIDINE/NOR
CRAUGSODINE
REDUCTASE
(Narcissus
pseudonarcissus) 		5 / 12 VAL A  42
ALA A  28
VAL A  30
GLY A 155
THR A 154
 None
 1.25A 5igiA-5feuA:
undetectable		 5igiA-5feuA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5feu NOROXOMARITIDINE/NOR
CRAUGSODINE
REDUCTASE
(Narcissus
pseudonarcissus) 		5 / 12 ILE A  37
VAL A  42
ALA A  28
LEU A 104
GLY A 155
 NAP  A 301 (-3.8A)
None
None
None
None
 0.91A 5igtA-5feuA:
undetectable		 5igtA-5feuA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5feu NOROXOMARITIDINE/NOR
CRAUGSODINE
REDUCTASE
(Narcissus
pseudonarcissus) 		5 / 12 ILE A 203
ALA A  28
VAL A  30
LEU A 104
THR A 154
 None
 1.00A 5igtA-5feuA:
undetectable		 5igtA-5feuA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5feu NOROXOMARITIDINE/NOR
CRAUGSODINE
REDUCTASE
(Narcissus
pseudonarcissus) 		6 / 12 VAL A  42
ALA A  28
VAL A  30
LEU A 104
GLY A 155
THR A 154
 None
 1.36A 5igtA-5feuA:
undetectable		 5igtA-5feuA:
19.94