SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ff5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 5ff5 PAAA
(Pantoea
agglomerans) 		4 / 8 HIS A 280
GLY A 282
LEU A 275
ASP A 277
 None
 0.78A 1aegA-5ff5A:
undetectable		 1aegA-5ff5A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 5ff5 PAAA
(Pantoea
agglomerans) 		3 / 3 ASP A 119
ASP A 117
LYS A 349
 None
 1.16A 1lqtB-5ff5A:
6.4		 1lqtB-5ff5A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 5ff5 PAAA
(Pantoea
agglomerans) 		3 / 3 ALA A  48
VAL A  43
TRP A  42
 None
 0.75A 1micA-5ff5A:
undetectable
1micB-5ff5A:
undetectable		 1micA-5ff5A:
5.26
1micB-5ff5A:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 5ff5 PAAA
(Pantoea
agglomerans) 		5 / 12 GLY A 144
GLY A 141
THR A 145
LEU A 177
ILE A 137
 None
SO4  A 401 ( 3.7A)
None
None
None
 0.95A 2wa2B-5ff5A:
3.6		 2wa2B-5ff5A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 5ff5 PAAA
(Pantoea
agglomerans) 		5 / 12 GLY A 144
GLY A 141
THR A 145
LEU A 177
ILE A 137
 None
SO4  A 401 ( 3.7A)
None
None
None
 0.95A 3gczA-5ff5A:
3.6		 3gczA-5ff5A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_0
(UNCHARACTERIZED
PROTEIN)		 5ff5 PAAA
(Pantoea
agglomerans) 		5 / 12 CYH A 147
LEU A 177
ILE A 162
LEU A 230
ILE A 247
 None
 1.13A 3ijdB-5ff5A:
undetectable		 3ijdB-5ff5A:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5ff5 PAAA
(Pantoea
agglomerans) 		5 / 12 VAL A 204
ILE A 156
VAL A 340
ILE A 259
LEU A 161
 None
 1.29A 4a84A-5ff5A:
undetectable		 4a84A-5ff5A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 5ff5 PAAA
(Pantoea
agglomerans) 		5 / 12 GLY A 144
GLY A 141
THR A 145
LEU A 177
GLN A 175
 None
SO4  A 401 ( 3.7A)
None
None
SO4  A 401 (-3.7A)
 1.23A 4f84A-5ff5A:
4.8		 4f84A-5ff5A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 5ff5 PAAA
(Pantoea
agglomerans) 		5 / 12 GLY A 144
GLY A 142
THR A 145
LEU A 177
GLN A 175
 None
SO4  A 401 (-3.6A)
None
None
SO4  A 401 (-3.7A)
 1.24A 4f84A-5ff5A:
4.8		 4f84A-5ff5A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZPH_A_PRLA501_0
(ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
ENDOTHELIAL PAS
DOMAIN-CONTAINING
PROTEIN 1)		 5ff5 PAAA
(Pantoea
agglomerans) 		4 / 7 GLN A 127
LEU A  98
SER A  99
GLU A 101
 None
 1.04A 4zphA-5ff5A:
undetectable
4zphB-5ff5A:
undetectable		 4zphA-5ff5A:
21.79
4zphB-5ff5A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB308_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5ff5 PAAA
(Pantoea
agglomerans) 		3 / 3 LEU A 159
ILE A 195
TYR A 178
 None
 0.68A 5uunB-5ff5A:
undetectable		 5uunB-5ff5A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 5ff5 PAAA
(Pantoea
agglomerans) 		6 / 12 VAL A 135
SER A 225
THR A 226
VAL A 202
GLY A 157
SER A 133
 None
 1.49A 6a94B-5ff5A:
undetectable		 6a94B-5ff5A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5ff5 PAAA
(Pantoea
agglomerans) 		4 / 5 GLN A 339
VAL A 340
PRO A 350
THR A 226
 None
 1.48A 6cduA-5ff5A:
undetectable
6cduB-5ff5A:
undetectable		 6cduA-5ff5A:
22.06
6cduB-5ff5A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_I_EY4I500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5ff5 PAAA
(Pantoea
agglomerans) 		4 / 5 GLN A 339
VAL A 340
PRO A 350
THR A 226
 None
 1.37A 6cduI-5ff5A:
undetectable
6cduJ-5ff5A:
undetectable		 6cduI-5ff5A:
22.06
6cduJ-5ff5A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 5ff5 PAAA
(Pantoea
agglomerans) 		4 / 7 ILE A 156
GLU A 205
HIS A 203
VAL A 202
 None
 1.05A 6j20A-5ff5A:
undetectable		 6j20A-5ff5A:
22.76