SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ff8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDW_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 5ff8 G/T
MISMATCH-SPECIFIC
THYMINE DNA
GLYCOSYLASE
(Homo
sapiens) 		5 / 10 PRO A 260
TYR A 235
SER A 239
VAL A 242
MET A 192
 None
 1.31A 1fdwA-5ff8A:
undetectable		 1fdwA-5ff8A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 5ff8 G/T
MISMATCH-SPECIFIC
THYMINE DNA
GLYCOSYLASE
(Homo
sapiens) 		5 / 10 PHE A 189
ILE A 137
LEU A 132
THR A 264
ILE A 259
 None
 1.27A 1i18A-5ff8A:
undetectable
1i18B-5ff8A:
undetectable		 1i18A-5ff8A:
18.39
1i18B-5ff8A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5ff8 G/T
MISMATCH-SPECIFIC
THYMINE DNA
GLYCOSYLASE
(Homo
sapiens) 		4 / 6 SER A 273
ARG A 275
PRO A 198
GLY A 199
 None
 1.29A 2y7pA-5ff8A:
undetectable		 2y7pA-5ff8A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIY_A_OAQA302_0
(SULFOTRANSFERASE)		 5ff8 G/T
MISMATCH-SPECIFIC
THYMINE DNA
GLYCOSYLASE
(Homo
sapiens) 		5 / 11 MET A 192
ILE A 137
VAL A 216
PHE A 229
LEU A 128
 None
 1.38A 5tiyA-5ff8A:
undetectable		 5tiyA-5ff8A:
20.74