SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ffj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_A_T3A1_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		5 / 12 ILE A1345
ARG A1414
LEU A1359
LEU A1449
PHE A1401
 None
 1.15A 1bsxA-5ffjA:
undetectable		 1bsxA-5ffjA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_B_T3B2_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		5 / 12 ILE A1345
ARG A1414
LEU A1359
LEU A1449
PHE A1401
 None
 1.15A 1bsxB-5ffjA:
undetectable		 1bsxB-5ffjA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		6 / 12 PHE A 997
LEU A 777
PHE A 752
PHE A 814
ALA A 770
LEU A 947
 None
 1.46A 1fe2A-5ffjA:
undetectable		 1fe2A-5ffjA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XPQ_C_SPMC921_1
(FMS1 PROTEIN)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		5 / 11 ASN A1073
LEU A1098
LYS A1148
PHE A1106
LEU A1102
 None
 1.41A 1xpqC-5ffjA:
1.5		 1xpqC-5ffjA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		4 / 5 PRO A1020
PRO A 903
ILE A1015
GLY A1017
 None
 1.11A 2jkjD-5ffjA:
undetectable		 2jkjD-5ffjA:
7.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		4 / 5 PRO A1020
PRO A 903
ILE A1015
GLY A1017
 None
 1.10A 2jkjF-5ffjA:
undetectable		 2jkjF-5ffjA:
7.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_A_CLUA808_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		4 / 7 ALA A 340
TYR A 404
TYR A 372
TYR A 315
 None
 1.22A 2pncA-5ffjA:
undetectable		 2pncA-5ffjA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_A_SAMA298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		7 / 12 PRO A1020
PHE A 904
GLY A 906
THR A 907
THR A 909
GLU A 944
VAL A 946
 None
 0.64A 2zifA-5ffjA:
2.6		 2zifA-5ffjA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_A_SAMA298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		7 / 12 PRO A1020
PHE A 910
PHE A 904
GLY A 906
THR A 907
THR A 909
VAL A 946
 None
 1.26A 2zifA-5ffjA:
2.6		 2zifA-5ffjA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		6 / 12 PRO A1020
PHE A 910
PHE A 904
GLY A 906
THR A 907
VAL A 946
 None
 1.21A 2zifB-5ffjA:
2.0		 2zifB-5ffjA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		5 / 12 TYR A1403
LEU A1431
GLY A1441
ILE A1360
LEU A1408
 None
 1.22A 2zzmA-5ffjA:
10.9		 2zzmA-5ffjA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_B_SAMB402_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		5 / 12 PHE A 868
PHE A 904
GLY A 906
ILE A 945
ASP A 981
 None
 0.97A 2zznB-5ffjA:
10.7		 2zznB-5ffjA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_A_TMQA611_1
(DHFR-TS)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		5 / 11 VAL A 320
ALA A 324
ILE A 335
LEU A 233
ILE A 318
 None
 1.07A 3clbA-5ffjA:
undetectable		 3clbA-5ffjA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GRV_A_ADNA300_1
(DIMETHYLADENOSINE
TRANSFERASE)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		5 / 11 GLU A 944
ILE A 945
ASP A 981
ASN A1018
PRO A1020
 None
 0.69A 3grvA-5ffjA:
13.5		 3grvA-5ffjA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_A_TMQA611_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		5 / 10 VAL A 320
ALA A 324
ILE A 335
LEU A 233
ILE A 318
 None
 1.06A 3hbbA-5ffjA:
3.0		 3hbbA-5ffjA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J7Z_A_ERYA9000_0
(23S RRNA
50S RIBOSOMAL
PROTEIN L22
ERMCL NASCENT CHAIN)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		3 / 3 LYS A1422
ILE A1111
PHE A1112
 None
 0.67A 3j7zS-5ffjA:
undetectable
3j7za-5ffjA:
undetectable		 3j7zS-5ffjA:
6.54
3j7za-5ffjA:
1.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		3 / 3 ASN A1086
ASP A1117
ARG A1375
 None
 0.94A 3k13C-5ffjA:
undetectable		 3k13C-5ffjA:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3006_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		4 / 6 ASN A 761
ILE A 945
GLU A 984
ASN A 759
 None
 1.16A 3kp6A-5ffjA:
undetectable
3kp6B-5ffjA:
undetectable		 3kp6A-5ffjA:
7.39
3kp6B-5ffjA:
7.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_C_OBNC1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		5 / 11 LEU A 979
VAL A 798
ALA A 801
PHE A 752
PHE A 749
 None
 1.43A 3n23C-5ffjA:
undetectable		 3n23C-5ffjA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NHX_A_ASDA126_1
(STEROID
DELTA-ISOMERASE)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		5 / 12 TYR A1048
LEU A1098
PHE A1106
ALA A1071
PHE A1083
 None
 1.44A 3nhxA-5ffjA:
undetectable		 3nhxA-5ffjA:
6.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R94_A_FLRA332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		5 / 12 LEU A 821
TYR A 825
SER A 774
PHE A 853
PHE A 857
 None
 1.34A 3r94A-5ffjA:
undetectable		 3r94A-5ffjA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_0
(PUTATIVE REGULATORY
PROTEIN)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		5 / 12 LEU A 947
SER A 949
TYR A 951
VAL A 828
PHE A 783
 None
 1.13A 3vw1D-5ffjA:
2.1		 3vw1D-5ffjA:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_1
(METHYLTRANSFERASE
MPPJ)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		3 / 3 ARG A 370
ASP A 333
ASP A 223
 None
 0.85A 4kicB-5ffjA:
10.3		 4kicB-5ffjA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_1
(DIHYDROFOLATE
REDUCTASE)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		5 / 12 ILE A1217
ALA A1211
ARG A1375
LEU A1408
ILE A1428
 None
 0.94A 4m2xA-5ffjA:
undetectable		 4m2xA-5ffjA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_E_TMQE202_1
(DIHYDROFOLATE
REDUCTASE)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		5 / 12 ILE A1217
ALA A1211
ARG A1375
LEU A1408
ILE A1428
 None
 0.91A 4m2xE-5ffjA:
undetectable		 4m2xE-5ffjA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		4 / 6 PRO A 903
ILE A1081
VAL A1084
ARG A1069
 None
 1.12A 4xe5A-5ffjA:
1.6		 4xe5A-5ffjA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		4 / 5 GLY A1059
TYR A1089
SER A1088
ASP A1062
 None
 1.36A 4xueA-5ffjA:
10.5		 4xueA-5ffjA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_A_SAMA301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		6 / 12 ASP A 981
PRO A1020
PHE A 904
GLY A 906
THR A 909
GLU A 944
 None
 0.77A 5hfjA-5ffjA:
2.0		 5hfjA-5ffjA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_C_SAMC301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		5 / 12 ASP A 981
PRO A1020
PHE A 904
GLY A 906
THR A 909
 None
 0.79A 5hfjC-5ffjA:
2.8		 5hfjC-5ffjA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_D_SAMD301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		6 / 12 ASP A 981
PRO A1020
PHE A 904
GLY A 906
THR A 909
GLU A 944
 None
 0.84A 5hfjD-5ffjA:
2.8		 5hfjD-5ffjA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_E_SAME301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		5 / 12 ASP A 981
PHE A 904
GLY A 906
THR A 909
GLU A 944
 None
 0.90A 5hfjE-5ffjA:
2.9		 5hfjE-5ffjA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_F_SAMF301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		5 / 12 ASP A 981
PRO A1020
PHE A 904
GLY A 906
GLU A 944
 None
 0.63A 5hfjF-5ffjA:
3.0		 5hfjF-5ffjA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		6 / 11 PHE A 904
GLY A 906
GLU A 944
ILE A 945
ASP A 981
PRO A1020
 None
 0.79A 5hjiA-5ffjA:
3.0		 5hjiA-5ffjA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		3 / 3 TYR A1204
TYR A1437
SER A1410
 None
 0.70A 5iktB-5ffjA:
undetectable		 5iktB-5ffjA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		4 / 4 GLU A1498
PRO A1497
ILE A1496
LEU A1482
 None
 1.07A 5m45A-5ffjA:
undetectable		 5m45A-5ffjA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		4 / 4 GLU A1498
PRO A1497
ILE A1496
LEU A1482
 None
 1.08A 5m45D-5ffjA:
undetectable		 5m45D-5ffjA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		4 / 4 GLU A1498
PRO A1497
ILE A1496
LEU A1482
 None
 1.04A 5m45G-5ffjA:
undetectable		 5m45G-5ffjA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		4 / 4 GLU A1498
PRO A1497
ILE A1496
LEU A1482
 None
 1.07A 5m45J-5ffjA:
undetectable		 5m45J-5ffjA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V4V_A_NCAA402_0
(NADPH DEHYDROGENASE
3)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		4 / 8 THR A1358
TYR A1503
PHE A1313
PRO A1312
 None
 1.15A 5v4vA-5ffjA:
undetectable		 5v4vA-5ffjA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V4V_B_NCAB402_0
(NADPH DEHYDROGENASE
3)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		4 / 8 THR A1358
TYR A1503
PHE A1313
PRO A1312
 None
 1.18A 5v4vB-5ffjA:
undetectable		 5v4vB-5ffjA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		3 / 3 GLY A 367
ASN A 362
ARG A 198
 None
 0.63A 5w7bD-5ffjA:
undetectable		 5w7bD-5ffjA:
4.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		5 / 12 GLY A 906
THR A 907
GLY A 908
THR A 982
ASN A1018
 None
 1.01A 5ybbA-5ffjA:
20.8		 5ybbA-5ffjA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		5 / 12 THR A 869
ASP A 902
THR A 907
ASN A1018
PRO A1020
 None
 0.70A 5ybbB-5ffjA:
20.7		 5ybbB-5ffjA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		4 / 7 GLY A 906
GLY A 908
GLU A 944
THR A 982
 None
 0.74A 5ybbB-5ffjA:
20.8		 5ybbB-5ffjA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		3 / 3 TYR A1518
ASP A1516
GLN A1517
 None
 0.89A 6g1pA-5ffjA:
undetectable		 6g1pA-5ffjA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I0Y_A_TRPA3001_0
(23S RIBOSOMAL RNA
TRYPTOPHANASE OPERON
LEADER PEPTIDE)		 5ffj ENDONUCLEASE AND
METHYLASE LLAGI
(Lactococcus
lactis) 		3 / 3 TRP A1513
ILE A1515
ASP A1516
 None
 0.75A 6i0y7-5ffjA:
undetectable		 6i0y7-5ffjA:
1.56