SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ffn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 12 ALA A 168
ALA A 167
VAL A 235
ILE A 247
HIS A  75
None
1.04A 1fm6U-5ffnA:
undetectable
1fm6U-5ffnA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
4 / 7 PHE A 207
ALA A 253
LEU A 193
ALA A 205
None
0.93A 2vcvL-5ffnA:
undetectable
2vcvL-5ffnA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
4 / 5 GLN A   6
THR A   5
THR A  79
HIS A 256
None
1.39A 2zj0A-5ffnA:
4.1
2zj0A-5ffnA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_2
(ADENOSYLHOMOCYSTEINA
SE)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
4 / 5 GLN A   6
THR A   5
THR A  79
HIS A 256
None
1.38A 2zj0C-5ffnA:
4.1
2zj0C-5ffnA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXZ_A_ADNA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 12 GLY A 179
GLY A 169
ILE A 221
GLY A 182
GLY A 183
None
None
None
NA  A 403 (-4.6A)
NA  A 403 (-3.9A)
0.80A 3axzA-5ffnA:
3.5
3axzA-5ffnA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
4 / 5 GLN A   6
THR A   5
THR A  79
HIS A 256
None
1.37A 3ce6C-5ffnA:
undetectable
3ce6C-5ffnA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
4 / 8 GLY A 232
GLY A  10
ILE A  11
THR A  79
None
0.67A 3d41A-5ffnA:
2.5
3d41A-5ffnA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_2
(ADENOSYLHOMOCYSTEINA
SE)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
4 / 4 GLN A   6
THR A   5
THR A  79
HIS A 256
None
1.34A 3g1uA-5ffnA:
4.1
3g1uA-5ffnA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_2
(ADENOSYLHOMOCYSTEINA
SE)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
4 / 5 GLN A   6
THR A   5
THR A  79
HIS A 256
None
1.36A 3g1uC-5ffnA:
3.2
3g1uC-5ffnA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_2
(ADENOSYLHOMOCYSTEINA
SE)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
4 / 5 GLN A   6
THR A   5
THR A  79
HIS A 256
None
1.37A 3glqA-5ffnA:
undetectable
3glqA-5ffnA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_2
(ADENOSYLHOMOCYSTEINA
SE)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
4 / 5 GLN A   6
THR A   5
THR A  79
HIS A 256
None
1.38A 3glqB-5ffnA:
2.5
3glqB-5ffnA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 12 ALA A 167
VAL A  76
GLY A  78
ALA A  77
LEU A 100
None
1.01A 3ln1A-5ffnA:
undetectable
3ln1A-5ffnA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 12 ALA A 167
VAL A  76
GLY A  78
ALA A  77
LEU A 100
None
1.00A 3ln1B-5ffnA:
undetectable
3ln1B-5ffnA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 12 ALA A 167
VAL A  76
GLY A  78
ALA A  77
LEU A 100
None
1.01A 3ln1C-5ffnA:
undetectable
3ln1C-5ffnA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 12 ALA A 167
VAL A  76
GLY A  78
ALA A  77
LEU A 100
None
1.00A 3ln1D-5ffnA:
undetectable
3ln1D-5ffnA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
4 / 5 GLN A   6
THR A   5
THR A  79
HIS A 256
None
1.35A 3n58A-5ffnA:
undetectable
3n58A-5ffnA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
3 / 3 LYS A 160
ARG A 122
LYS A  53
None
1.39A 3okxA-5ffnA:
undetectable
3okxA-5ffnA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 10 ILE A 121
SER A 140
ASN A 138
ILE A 164
ALA A 157
None
1.42A 3u6tA-5ffnA:
undetectable
3u6tA-5ffnA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_C_SVRC516_1
(RNA-DEPENDENT RNA
POLYMERASE)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 9 GLY A  47
ALA A  46
ALA A  82
ASP A  44
LEU A  43
None
1.47A 3ur0C-5ffnA:
undetectable
3ur0C-5ffnA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_0
(PUTATIVE REGULATORY
PROTEIN)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 12 LEU A 260
THR A   7
ILE A  11
ILE A 264
ALA A 267
None
1.12A 3vw1D-5ffnA:
undetectable
3vw1D-5ffnA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
4 / 7 VAL A 228
TYR A 287
TYR A 307
LEU A 260
None
0.83A 4b3qA-5ffnA:
2.4
4b3qA-5ffnA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4
SERINE/THREONINE-PRO
TEIN KINASE MTOR)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
4 / 8 LEU A 141
SER A 251
THR A  74
ASP A  68
None
1.04A 4drjB-5ffnA:
undetectable
4drjB-5ffnA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_A_TEPA402_1
(PYRIDOXAL KINASE)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
4 / 5 SER A  86
GLY A  85
VAL A   2
ASP A  44
None
1.00A 4eohA-5ffnA:
5.8
4eohA-5ffnA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 12 GLY A  73
GLY A  71
THR A  36
LEU A 106
GLN A  70
None
1.10A 4f84A-5ffnA:
undetectable
4f84A-5ffnA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_1
(PROTEASE)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 11 ALA A 191
ILE A 289
GLY A 292
ILE A 293
ILE A 226
None
0.87A 4njtC-5ffnA:
undetectable
4njtC-5ffnA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 12 ALA A 187
ALA A 118
ILE A 121
LEU A 141
MET A 139
NA  A 403 (-4.3A)
None
None
None
None
1.08A 4r38A-5ffnA:
undetectable
4r38A-5ffnA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 12 ALA A 187
ALA A 118
ILE A 121
LEU A 141
MET A 139
NA  A 403 (-4.3A)
None
None
None
None
1.06A 4r38C-5ffnA:
undetectable
4r38C-5ffnA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 12 ALA A 187
ALA A 118
ILE A 121
LEU A 141
MET A 139
NA  A 403 (-4.3A)
None
None
None
None
1.07A 4r38D-5ffnA:
undetectable
4r38D-5ffnA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 12 ALA A 187
ALA A 118
ILE A 121
LEU A 141
MET A 139
NA  A 403 (-4.3A)
None
None
None
None
1.12A 4r3aA-5ffnA:
undetectable
4r3aA-5ffnA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RN6_B_15UB301_1
(THROMBIN HEAVY CHAIN)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 12 TYR A 240
TRP A 239
VAL A 105
GLY A 110
GLY A 112
None
1.02A 4rn6B-5ffnA:
undetectable
4rn6B-5ffnA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 12 GLY A 179
GLY A 169
ILE A 221
GLY A 182
GLY A 183
None
None
None
NA  A 403 (-4.6A)
NA  A 403 (-3.9A)
0.84A 4yvgA-5ffnA:
2.5
4yvgA-5ffnA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
4 / 5 LEU A 276
ALA A 262
LEU A 163
VAL A  94
None
1.20A 5cr1A-5ffnA:
undetectable
5cr1A-5ffnA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_A_SAMA601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 12 TYR A 307
GLY A 259
LEU A  81
VAL A  76
VAL A  33
None
0.99A 5dpdA-5ffnA:
undetectable
5dpdA-5ffnA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 12 ALA A 167
VAL A  76
GLY A  78
ALA A  77
LEU A 100
None
1.02A 5jw1A-5ffnA:
undetectable
5jw1A-5ffnA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 12 ALA A 167
VAL A  76
GLY A  78
ALA A  77
LEU A 100
None
1.02A 5jw1B-5ffnA:
undetectable
5jw1B-5ffnA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_ACTA405_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
3 / 3 GLN A 222
THR A 215
ASP A 225
CA  A 401 (-3.0A)
CA  A 401 (-4.9A)
CA  A 401 (-2.9A)
0.80A 5k9dA-5ffnA:
undetectable
5k9dA-5ffnA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 12 ALA A 167
VAL A  76
GLY A  78
ALA A  77
LEU A 100
None
0.98A 5kirA-5ffnA:
undetectable
5kirA-5ffnA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 12 VAL A  31
ALA A 167
VAL A  76
GLY A  78
ALA A  77
None
1.06A 5kirA-5ffnA:
undetectable
5kirA-5ffnA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 12 ALA A 167
VAL A  76
GLY A  78
ALA A  77
LEU A 100
None
0.99A 5kirB-5ffnA:
undetectable
5kirB-5ffnA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 12 VAL A  31
ALA A 167
VAL A  76
GLY A  78
ALA A  77
None
1.06A 5kirB-5ffnA:
undetectable
5kirB-5ffnA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 12 GLY A  73
GLY A  71
THR A  36
GLN A  70
VAL A  33
None
1.17A 5kocB-5ffnA:
undetectable
5kocB-5ffnA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_B_RBFB502_1
(RIBOFLAVIN LYASE)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 12 SER A 229
ALA A 167
GLY A 249
GLY A 292
ALA A 295
None
0.95A 5w4zB-5ffnA:
1.7
5w4zB-5ffnA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_A_SAMA401_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 12 GLY A 179
GLY A 169
ILE A 221
GLY A 182
GLY A 183
None
None
None
NA  A 403 (-4.6A)
NA  A 403 (-3.9A)
0.91A 5wyqA-5ffnA:
2.6
5wyqA-5ffnA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC901_0
(MRNA CAPPING ENZYME
P5)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
5 / 11 VAL A  38
GLY A  73
SER A 140
ALA A 102
LEU A 100
None
1.25A 5x6yC-5ffnA:
undetectable
5x6yC-5ffnA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
4 / 5 GLN A   6
THR A   5
THR A  79
HIS A 256
None
1.42A 6aphA-5ffnA:
4.5
6aphA-5ffnA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_A_ADNA505_2
(-)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
4 / 4 GLN A   6
THR A   5
THR A  79
HIS A 256
None
1.42A 6f3nA-5ffnA:
2.5
6f3nA-5ffnA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_C_ADNC505_2
(-)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
4 / 4 GLN A   6
THR A   5
THR A  79
HIS A 256
None
1.42A 6f3nC-5ffnA:
undetectable
6f3nC-5ffnA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_D_ADND506_2
(-)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
4 / 4 GLN A   6
THR A   5
THR A  79
HIS A 256
None
1.42A 6f3nD-5ffnA:
3.5
6f3nD-5ffnA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)
5ffn ENZYME SUBTILASE
SUBTY FROM BACILLUS
SP. TY145

(Bacillus
sp.
(in:
Bacteria))
4 / 5 GLN A   6
THR A   5
HIS A  75
GLY A  84
None
1.18A 6gbnC-5ffnA:
3.3
6gbnC-5ffnA:
24.43