SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ffo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 5ffo INTEGRIN BETA-6
(Homo
sapiens) 		4 / 8 ILE B 196
MET B 122
ASN B 212
LEU B 124
 None
 0.99A 1dzmA-5ffoB:
undetectable		 1dzmA-5ffoB:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 5ffo INTEGRIN BETA-6
(Homo
sapiens) 		3 / 3 PHE B 311
LEU B 320
SER B 257
 None
 0.69A 1e7aA-5ffoB:
undetectable		 1e7aA-5ffoB:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 5ffo INTEGRIN BETA-6
(Homo
sapiens) 		4 / 8 ALA B 312
VAL B 252
LEU B 138
THR B 134
 None
 0.91A 2it4A-5ffoB:
undetectable		 2it4A-5ffoB:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_D_ROFD904_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5ffo TRANSFORMING GROWTH
FACTOR BETA-1
(Homo
sapiens) 		3 / 3 ASN C 155
MET C 104
PHE C 169
 None
 1.04A 3g4lD-5ffoC:
undetectable		 3g4lD-5ffoC:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 5ffo TRANSFORMING GROWTH
FACTOR BETA-1
(Homo
sapiens) 		3 / 3 LYS C  77
ARG C  29
LYS C 319
 None
 1.22A 3okxA-5ffoC:
undetectable		 3okxA-5ffoC:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VWQ_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5ffo INTEGRIN BETA-6
(Homo
sapiens) 		5 / 12 ALA B 266
TYR B 284
ASP B 227
GLY B 267
ILE B 268
 None
 1.18A 3vwqA-5ffoB:
undetectable		 3vwqA-5ffoB:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 5ffo INTEGRIN BETA-6
(Homo
sapiens) 		5 / 12 GLY B 334
ALA B 312
VAL B 252
LEU B 138
ILE B 347
 None
 1.21A 4pd5A-5ffoB:
undetectable		 4pd5A-5ffoB:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_B_ML1B302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5ffo INTEGRIN BETA-6
(Homo
sapiens) 		4 / 6 GLY B 224
PHE B 251
ILE B 229
PHE B 311
 None
 0.79A 4qogA-5ffoB:
4.5
4qogB-5ffoB:
4.4		 4qogA-5ffoB:
20.75
4qogB-5ffoB:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 5ffo INTEGRIN BETA-6
(Homo
sapiens) 		3 / 3 GLY B 274
GLN B 231
LYS B 301
 None
 0.91A 5imsB-5ffoB:
3.5		 5imsB-5ffoB:
17.23