SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ffp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGP_A_PCFA1213_0 (WNT INHIBITORY FACTOR 1)	5ffp	IMMUNITY 23 FAMILY PROTEIN (Burkholderia dolosa)	5 / 12	LEU A 29 MET A 33 VAL A 147 VAL A 151 PHE A 144	None	1.00A	2ygpA-5ffpA: undetectable	2ygpA-5ffpA: 20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D91_B_REMB350_1 (RENIN)	5ffp	IMMUNITY 23 FAMILY PROTEIN (Burkholderia dolosa)	5 / 12	SER A 40 LEU A 45 ASP A 48 ALA A 102 SER A 101	None	1.19A	3d91B-5ffpA: undetectable	3d91B-5ffpA: 19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C9K_B_CAMB424_0 (CYTOCHROME P450)	5ffp	IMMUNITY 23 FAMILY PROTEIN (Burkholderia dolosa)	5 / 9	LEU A 105 LEU A 29 GLY A 30 VAL A 148 VAL A 151	None	1.31A	4c9kB-5ffpA: undetectable	4c9kB-5ffpA: 14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C9N_B_CAMB1420_0 (CYTOCHROME P450)	5ffp	IMMUNITY 23 FAMILY PROTEIN (Burkholderia dolosa)	5 / 10	LEU A 105 LEU A 29 GLY A 30 VAL A 148 VAL A 151	None	1.32A	4c9nB-5ffpA: undetectable	4c9nB-5ffpA: 14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C9P_A_CAMA423_0 (CYTOCHROME P450)	5ffp	IMMUNITY 23 FAMILY PROTEIN (Burkholderia dolosa)	5 / 9	LEU A 105 LEU A 29 GLY A 30 VAL A 148 VAL A 151	None	1.33A	4c9pA-5ffpA: undetectable	4c9pA-5ffpA: 14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C9P_B_CAMB423_0 (CYTOCHROME P450)	5ffp	IMMUNITY 23 FAMILY PROTEIN (Burkholderia dolosa)	5 / 10	LEU A 105 LEU A 29 GLY A 30 VAL A 148 VAL A 151	None	1.33A	4c9pB-5ffpA: undetectable	4c9pB-5ffpA: 14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CP4_A_CAMA416_0 (CYTOCHROME P450-CAM)	5ffp	IMMUNITY 23 FAMILY PROTEIN (Burkholderia dolosa)	4 / 7	PHE A 9 LEU A 105 VAL A 151 VAL A 148	None	0.98A	4cp4A-5ffpA: undetectable	4cp4A-5ffpA: 19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FO4_A_MOAA502_1 (INOSINE 5'-MONOPHOSPHATE DEHYDROGENASE)	5ffp	IMMUNITY 23 FAMILY PROTEIN (Burkholderia dolosa)	4 / 8	ASP A 107 SER A 104 SER A 43 ASN A 42	None	0.96A	4fo4A-5ffpA: undetectable	4fo4A-5ffpA: 18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MN4_E_AM2E301_0 (AMINOGLYCOSIDE N(3)-ACETYLTRANSFERA SE, AAC(3)-IVA)	5ffp	IMMUNITY 23 FAMILY PROTEIN (Burkholderia dolosa)	4 / 7	HIS A 98 THR A 97 ARG A 141 GLU A 116	None	1.31A	6mn4E-5ffpA: undetectable	6mn4E-5ffpA: 21.59

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2YGP_A_PCFA1213_0","WNT INHIBITORY FACTOR 1","5ffp","IMMUNITY 23 FAMILY PROTEIN","Burkholderia dolosa",5,"LEU A  29;MET A  33;VAL A 147;VAL A 151;PHE A 144","None","1.00A","2ygpA-5ffpA:undetectable","2ygpA-5ffpA:20.90"],["3D91_B_REMB350_1","RENIN","5ffp","IMMUNITY 23 FAMILY PROTEIN","Burkholderia dolosa",5,"SER A  40;LEU A  45;ASP A  48;ALA A 102;SER A 101","None","1.19A","3d91B-5ffpA:undetectable","3d91B-5ffpA:19.83"],["4C9K_B_CAMB424_0","CYTOCHROME P450","5ffp","IMMUNITY 23 FAMILY PROTEIN","Burkholderia dolosa",5,"LEU A 105;LEU A  29;GLY A  30;VAL A 148;VAL A 151","None","1.31A","4c9kB-5ffpA:undetectable","4c9kB-5ffpA:14.92"],["4C9N_B_CAMB1420_0","CYTOCHROME P450","5ffp","IMMUNITY 23 FAMILY PROTEIN","Burkholderia dolosa",5,"LEU A 105;LEU A  29;GLY A  30;VAL A 148;VAL A 151","None","1.32A","4c9nB-5ffpA:undetectable","4c9nB-5ffpA:14.92"],["4C9P_A_CAMA423_0","CYTOCHROME P450","5ffp","IMMUNITY 23 FAMILY PROTEIN","Burkholderia dolosa",5,"LEU A 105;LEU A  29;GLY A  30;VAL A 148;VAL A 151","None","1.33A","4c9pA-5ffpA:undetectable","4c9pA-5ffpA:14.92"],["4C9P_B_CAMB423_0","CYTOCHROME P450","5ffp","IMMUNITY 23 FAMILY PROTEIN","Burkholderia dolosa",5,"LEU A 105;LEU A  29;GLY A  30;VAL A 148;VAL A 151","None","1.33A","4c9pB-5ffpA:undetectable","4c9pB-5ffpA:14.92"],["4CP4_A_CAMA416_0","CYTOCHROME P450-CAM","5ffp","IMMUNITY 23 FAMILY PROTEIN","Burkholderia dolosa",4,"PHE A   9;LEU A 105;VAL A 151;VAL A 148","None","0.98A","4cp4A-5ffpA:undetectable","4cp4A-5ffpA:19.07"],["4FO4_A_MOAA502_1","INOSINE 5'-MONOPHOSPHATE DEHYDROGENASE","5ffp","IMMUNITY 23 FAMILY PROTEIN","Burkholderia dolosa",4,"ASP A 107;SER A 104;SER A  43;ASN A  42","None","0.96A","4fo4A-5ffpA:undetectable","4fo4A-5ffpA:18.64"],["6MN4_E_AM2E301_0","AMINOGLYCOSIDE N(3)-ACETYLTRANSFERASE, AAC(3)-IVA","5ffp","IMMUNITY 23 FAMILY PROTEIN","Burkholderia dolosa",4,"HIS A  98;THR A  97;ARG A 141;GLU A 116","None","1.31A","6mn4E-5ffpA:undetectable","6mn4E-5ffpA:21.59"]]