SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fg6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ITA_D_AICD501_1 (D-ALANYL-D-ALANINE CARBOXYPEPTIDASE DACC)	5fg6	BROMODOMAIN-CONTAINI NG PROTEIN 1 (Homo sapiens)	3 / 3	PRO A 583 PHE A 587 ALA A 651	None 5XE A 705 (-4.4A) None	0.71A	3itaD-5fg6A: undetectable	3itaD-5fg6A: 17.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5PBE_A_TYLA2001_1 (BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B)	5fg6	BROMODOMAIN-CONTAINI NG PROTEIN 1 (Homo sapiens)	4 / 6	VAL A 591 VAL A 596 TYR A 599 ASN A 642	5XE A 705 (-3.9A) 5XE A 705 (-4.9A) None 5XE A 705 (-3.3A)	0.37A	5pbeA-5fg6A: 15.3	5pbeA-5fg6A: 31.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XOO_A_ADNA506_1 (GLYCOSAMINOGLYCAN XYLOSYLKINASE)	5fg6	BROMODOMAIN-CONTAINI NG PROTEIN 1 (Homo sapiens)	4 / 6	TYR A 621 LEU A 578 GLU A 628 LEU A 663	None None EDO A 703 (-3.1A) EDO A 703 ( 4.2A)	1.16A	5xooA-5fg6A: undetectable	5xooA-5fg6A: 20.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5Y1Y_A_HNQA201_1 (BROMODOMAIN-CONTAINI NG PROTEIN 4)	5fg6	BROMODOMAIN-CONTAINI NG PROTEIN 1 (Homo sapiens)	4 / 8	VAL A 591 CYH A 638 TYR A 641 ASN A 642	5XE A 705 (-3.9A) 5XE A 705 (-3.6A) 5XE A 705 (-4.8A) 5XE A 705 (-3.3A)	0.36A	5y1yA-5fg6A: 13.7	5y1yA-5fg6A: 32.61

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3ITA_D_AICD501_1","D-ALANYL-D-ALANINE CARBOXYPEPTIDASE DACC","5fg6","BROMODOMAIN-CONTAINING PROTEIN 1","Homo sapiens",3,"PRO A 583;PHE A 587;ALA A 651","None;5XE A 705 (-4.4A);None","0.71A","3itaD-5fg6A:undetectable","3itaD-5fg6A:17.97"],["5PBE_A_TYLA2001_1","BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B","5fg6","BROMODOMAIN-CONTAINING PROTEIN 1","Homo sapiens",4,"VAL A 591;VAL A 596;TYR A 599;ASN A 642","5XE A 705 (-3.9A);5XE A 705 (-4.9A);None;5XE A 705 (-3.3A)","0.37A","5pbeA-5fg6A:15.3","5pbeA-5fg6A:31.43"],["5XOO_A_ADNA506_1","GLYCOSAMINOGLYCAN XYLOSYLKINASE","5fg6","BROMODOMAIN-CONTAINING PROTEIN 1","Homo sapiens",4,"TYR A 621;LEU A 578;GLU A 628;LEU A 663","None;None;EDO A 703 (-3.1A);EDO A 703 ( 4.2A)","1.16A","5xooA-5fg6A:undetectable","5xooA-5fg6A:20.31"],["5Y1Y_A_HNQA201_1","BROMODOMAIN-CONTAINING PROTEIN 4","5fg6","BROMODOMAIN-CONTAINING PROTEIN 1","Homo sapiens",4,"VAL A 591;CYH A 638;TYR A 641;ASN A 642","5XE A 705 (-3.9A);5XE A 705 (-3.6A);5XE A 705 (-4.8A);5XE A 705 (-3.3A)","0.36A","5y1yA-5fg6A:13.7","5y1yA-5fg6A:32.61"]]