SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fg9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK9_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 10 LEU H 154
VAL H  13
VAL H   4
TYR H 124
LEU H 146
 None
 0.97A 1fk9A-5fg9H:
undetectable		 1fk9A-5fg9H:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKV_A_EFZA2000_1
(POL POLYPROTEIN)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 9 LEU H 154
VAL H  13
VAL H   4
TYR H 124
LEU H 146
 None
 1.11A 1ikvA-5fg9H:
undetectable		 1ikvA-5fg9H:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKW_A_EFZA2000_1
(POL POLYPROTEIN)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 10 LEU H 154
VAL H  13
VAL H   4
TYR H 124
LEU H 146
 None
 1.09A 1ikwA-5fg9H:
undetectable		 1ikwA-5fg9H:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 12 LEU H 167
GLY H 162
ASP H 166
ALA H 133
ALA H 136
 None
 1.19A 2br4B-5fg9H:
undetectable		 2br4B-5fg9H:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 12 LEU H 167
GLY H 162
ASP H 166
ALA H 133
ALA H 136
 None
 1.15A 2br4E-5fg9H:
undetectable		 2br4E-5fg9H:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.48A 2f162-5fg9H:
27.9		 2f162-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 11 THR H   1
GLN H  22
ALA H  27
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
 None
 0.61A 2f16H-5fg9H:
36.5
2f16I-5fg9H:
26.1		 2f16H-5fg9H:
98.23
2f16I-5fg9H:
23.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
SER H  20
GLN H  22
ALA H  27
LYS H  33
ALA H  46
ALA H  49
 None
 0.77A 2f16H-5fg9H:
36.5
2f16I-5fg9H:
26.1		 2f16H-5fg9H:
98.23
2f16I-5fg9H:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.52A 2f16K-5fg9H:
27.7
2f16L-5fg9H:
23.4		 2f16K-5fg9H:
29.22
2f16L-5fg9H:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.47A 2f16N-5fg9H:
27.9		 2f16N-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 11 THR H   1
GLN H  22
ALA H  27
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
 None
 0.62A 2f16V-5fg9H:
36.4
2f16W-5fg9H:
26.1		 2f16V-5fg9H:
98.23
2f16W-5fg9H:
23.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
SER H  20
GLN H  22
ALA H  27
LYS H  33
ALA H  46
ALA H  49
 None
 0.77A 2f16V-5fg9H:
36.4
2f16W-5fg9H:
26.1		 2f16V-5fg9H:
98.23
2f16W-5fg9H:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.51A 2f16Y-5fg9H:
16.1
2f16Z-5fg9H:
23.2		 2f16Y-5fg9H:
29.22
2f16Z-5fg9H:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 11 ILE H  41
GLU H  73
GLY H 107
THR H 106
GLY H 102
 None
 1.31A 2fn1A-5fg9H:
undetectable		 2fn1A-5fg9H:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 11 ILE H  41
GLU H  73
GLY H 107
THR H 106
GLY H 102
 None
 1.25A 2fn1B-5fg9H:
undetectable		 2fn1B-5fg9H:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP0_A_NVPA701_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 9 LEU H 154
VAL H  13
VAL H   4
TYR H 124
LEU H 146
 None
 1.03A 3lp0A-5fg9H:
undetectable		 3lp0A-5fg9H:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP1_A_NVPA701_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 10 LEU H 154
VAL H  13
VAL H   4
TYR H 124
LEU H 146
 None
 0.99A 3lp1A-5fg9H:
undetectable		 3lp1A-5fg9H:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 12 LEU H 154
VAL H  13
VAL H   4
TYR H 124
LEU H 146
 None
 1.16A 3mecA-5fg9H:
undetectable		 3mecA-5fg9H:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 12 VAL H  13
VAL H   4
TYR H 124
PHE H   8
LEU H 146
 None
 1.12A 3mecA-5fg9H:
undetectable		 3mecA-5fg9H:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 12 LEU H 154
VAL H  13
VAL H   4
TYR H 124
LEU H 146
 None
 1.14A 3medA-5fg9H:
undetectable
3medB-5fg9H:
undetectable		 3medA-5fg9H:
19.06
3medB-5fg9H:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 12 VAL H  13
VAL H   4
TYR H 124
PHE H   8
LEU H 146
 None
 1.07A 3medA-5fg9H:
undetectable
3medB-5fg9H:
undetectable		 3medA-5fg9H:
19.06
3medB-5fg9H:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEE_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 12 LEU H 154
VAL H  13
VAL H   4
TYR H 124
LEU H 146
 None
 0.99A 3meeA-5fg9H:
undetectable		 3meeA-5fg9H:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEG_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 12 LEU H 154
VAL H  13
VAL H   4
TYR H 124
LEU H 146
 None
 1.02A 3megA-5fg9H:
undetectable		 3megA-5fg9H:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 12 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.47A 3mg02-5fg9H:
27.8
3mg0V-5fg9H:
36.5		 3mg02-5fg9H:
29.41
3mg0V-5fg9H:
98.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
SER H  20
THR H  21
GLN H  22
LYS H  33
ALA H  46
ALA H  49
 None
 0.76A 3mg0H-5fg9H:
35.2
3mg0I-5fg9H:
22.1		 3mg0H-5fg9H:
98.23
3mg0I-5fg9H:
23.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 11 THR H   1
THR H  21
GLN H  22
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
 None
 0.60A 3mg0H-5fg9H:
35.2
3mg0I-5fg9H:
22.1		 3mg0H-5fg9H:
98.23
3mg0I-5fg9H:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 11 THR H   1
THR H  21
ALA H  27
LYS H  33
ALA H  46
GLY H  47
ALA H  49
SER H 129
 None
 0.49A 3mg0K-5fg9H:
27.7
3mg0L-5fg9H:
23.4		 3mg0K-5fg9H:
29.22
3mg0L-5fg9H:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.46A 3mg0N-5fg9H:
27.9		 3mg0N-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 11 THR H   1
GLN H  22
ALA H  27
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
 None
 0.69A 3mg0V-5fg9H:
36.5
3mg0W-5fg9H:
26.1		 3mg0V-5fg9H:
98.23
3mg0W-5fg9H:
23.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
SER H  20
GLN H  22
ALA H  27
LYS H  33
ALA H  46
ALA H  49
 None
 0.83A 3mg0V-5fg9H:
36.5
3mg0W-5fg9H:
26.1		 3mg0V-5fg9H:
98.23
3mg0W-5fg9H:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 12 THR H   1
THR H  21
ALA H  27
LYS H  33
ALA H  46
GLY H  47
ALA H  49
SER H 129
 None
 0.50A 3mg0Y-5fg9H:
16.1
3mg0Z-5fg9H:
23.2		 3mg0Y-5fg9H:
29.22
3mg0Z-5fg9H:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		4 / 8 LEU H 154
VAL H   4
TYR H 124
LEU H 146
 None
 0.59A 3v81C-5fg9H:
undetectable		 3v81C-5fg9H:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		4 / 8 LEU H 154
VAL H  13
VAL H   4
LEU H 146
 None
 0.89A 3v81C-5fg9H:
undetectable		 3v81C-5fg9H:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 12 HIS H 114
GLY H 128
TYR H  97
ALA H 158
LEU H 138
 None
 1.18A 3vywB-5fg9H:
undetectable		 3vywB-5fg9H:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 12 HIS H 114
GLY H 128
TYR H  97
ALA H 158
LEU H 138
 None
 1.16A 3vywD-5fg9H:
undetectable		 3vywD-5fg9H:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA603_1
(SERUM ALBUMIN)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 10 LEU H  34
VAL H   6
LEU H 138
LEU H 154
VAL H 137
 None
 1.15A 4po0A-5fg9H:
undetectable		 4po0A-5fg9H:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		4 / 8 LEU H 154
VAL H   4
TYR H 124
LEU H 146
 None
 0.68A 4pwdC-5fg9H:
undetectable		 4pwdC-5fg9H:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		4 / 8 LEU H 154
VAL H  13
VAL H   4
LEU H 146
 None
 0.99A 4pwdC-5fg9H:
undetectable		 4pwdC-5fg9H:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		4 / 8 LEU H 154
VAL H   4
TYR H 124
LEU H 146
 None
 0.75A 4q0bA-5fg9H:
undetectable		 4q0bA-5fg9H:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		4 / 8 LEU H 154
VAL H  13
VAL H   4
LEU H 146
 None
 0.99A 4q0bA-5fg9H:
undetectable		 4q0bA-5fg9H:
18.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.39A 4qvlV-5fg9H:
37.5
4qvlb-5fg9H:
28.1		 4qvlV-5fg9H:
98.31
4qvlb-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 9 THR H   1
SER H  20
GLN H  22
ALA H  46
ALA H  49
THR H  52
 None
 0.97A 4qvlH-5fg9H:
36.8
4qvlI-5fg9H:
22.1		 4qvlH-5fg9H:
98.31
4qvlI-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 9 THR H   1
SER H  20
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.64A 4qvlH-5fg9H:
36.8
4qvlI-5fg9H:
22.1		 4qvlH-5fg9H:
98.31
4qvlI-5fg9H:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.47A 4qvlK-5fg9H:
20.1
4qvlL-5fg9H:
23.4		 4qvlK-5fg9H:
29.22
4qvlL-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.41A 4qvlH-5fg9H:
36.8
4qvlN-5fg9H:
28.0		 4qvlH-5fg9H:
98.31
4qvlN-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
GLN H  22
ALA H  46
THR H  48
ALA H  49
THR H  52
 None
 0.84A 4qvlV-5fg9H:
37.5
4qvlW-5fg9H:
26.1		 4qvlV-5fg9H:
98.31
4qvlW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
LYS H  33
ALA H  46
THR H  48
ALA H  49
THR H  52
 None
 0.27A 4qvlV-5fg9H:
37.5
4qvlW-5fg9H:
26.1		 4qvlV-5fg9H:
98.31
4qvlW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
SER H  20
GLN H  22
ALA H  46
ALA H  49
THR H  52
 None
 0.97A 4qvlV-5fg9H:
37.5
4qvlW-5fg9H:
26.1		 4qvlV-5fg9H:
98.31
4qvlW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
SER H  20
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.64A 4qvlV-5fg9H:
37.5
4qvlW-5fg9H:
26.1		 4qvlV-5fg9H:
98.31
4qvlW-5fg9H:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.48A 4qvlY-5fg9H:
21.2
4qvlZ-5fg9H:
23.3		 4qvlY-5fg9H:
29.22
4qvlZ-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.41A 4qvmV-5fg9H:
37.2
4qvmb-5fg9H:
28.0		 4qvmV-5fg9H:
98.31
4qvmb-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
CYH H  31
LYS H  33
THR H  48
ALA H  49
THR H  52
 None
 0.35A 4qvmH-5fg9H:
36.6
4qvmI-5fg9H:
22.0		 4qvmH-5fg9H:
98.31
4qvmI-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
GLN H  22
CYH H  31
THR H  48
ALA H  49
THR H  52
 None
 0.96A 4qvmH-5fg9H:
36.6
4qvmI-5fg9H:
22.0		 4qvmH-5fg9H:
98.31
4qvmI-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
SER H  20
CYH H  31
LYS H  33
ALA H  49
THR H  52
 None
 0.67A 4qvmH-5fg9H:
36.6
4qvmI-5fg9H:
22.0		 4qvmH-5fg9H:
98.31
4qvmI-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
SER H  20
GLN H  22
CYH H  31
ALA H  49
THR H  52
 None
 1.03A 4qvmH-5fg9H:
36.6
4qvmI-5fg9H:
22.0		 4qvmH-5fg9H:
98.31
4qvmI-5fg9H:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 9 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.49A 4qvmK-5fg9H:
20.0
4qvmL-5fg9H:
23.3		 4qvmK-5fg9H:
29.22
4qvmL-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.43A 4qvmH-5fg9H:
36.6
4qvmN-5fg9H:
27.9		 4qvmH-5fg9H:
98.31
4qvmN-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
CYH H  31
LYS H  33
THR H  48
ALA H  49
THR H  52
 None
 0.34A 4qvmV-5fg9H:
37.2
4qvmW-5fg9H:
26.0		 4qvmV-5fg9H:
98.31
4qvmW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
GLN H  22
CYH H  31
THR H  48
ALA H  49
THR H  52
 None
 0.96A 4qvmV-5fg9H:
37.2
4qvmW-5fg9H:
26.0		 4qvmV-5fg9H:
98.31
4qvmW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
SER H  20
CYH H  31
LYS H  33
ALA H  49
THR H  52
 None
 0.66A 4qvmV-5fg9H:
37.2
4qvmW-5fg9H:
26.0		 4qvmV-5fg9H:
98.31
4qvmW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
SER H  20
GLN H  22
CYH H  31
ALA H  49
THR H  52
 None
 1.03A 4qvmV-5fg9H:
37.2
4qvmW-5fg9H:
26.0		 4qvmV-5fg9H:
98.31
4qvmW-5fg9H:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.48A 4qvmY-5fg9H:
21.0
4qvmZ-5fg9H:
23.1		 4qvmY-5fg9H:
29.22
4qvmZ-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 12 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.45A 4qvnV-5fg9H:
36.9
4qvnb-5fg9H:
28.0		 4qvnV-5fg9H:
98.31
4qvnb-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
CYH H  31
LYS H  33
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.45A 4qvnH-5fg9H:
36.4
4qvnI-5fg9H:
22.2		 4qvnH-5fg9H:
98.31
4qvnI-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
GLN H  22
CYH H  31
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.97A 4qvnH-5fg9H:
36.4
4qvnI-5fg9H:
22.2		 4qvnH-5fg9H:
98.31
4qvnI-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
SER H  20
CYH H  31
LYS H  33
ALA H  49
THR H  52
 None
 0.70A 4qvnH-5fg9H:
36.4
4qvnI-5fg9H:
22.2		 4qvnH-5fg9H:
98.31
4qvnI-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
SER H  20
GLN H  22
CYH H  31
ALA H  49
THR H  52
 None
 1.08A 4qvnH-5fg9H:
36.4
4qvnI-5fg9H:
22.2		 4qvnH-5fg9H:
98.31
4qvnI-5fg9H:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 9 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.52A 4qvnK-5fg9H:
20.1
4qvnL-5fg9H:
23.4		 4qvnK-5fg9H:
29.22
4qvnL-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 12 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.44A 4qvnH-5fg9H:
36.4
4qvnN-5fg9H:
27.9		 4qvnH-5fg9H:
98.31
4qvnN-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
GLN H  22
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.89A 4qvnV-5fg9H:
36.9
4qvnW-5fg9H:
26.2		 4qvnV-5fg9H:
98.31
4qvnW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
LYS H  33
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.36A 4qvnV-5fg9H:
36.9
4qvnW-5fg9H:
26.2		 4qvnV-5fg9H:
98.31
4qvnW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 10 THR H   1
SER H  20
GLN H  22
ALA H  49
THR H  52
 None
 1.09A 4qvnV-5fg9H:
36.9
4qvnW-5fg9H:
26.2		 4qvnV-5fg9H:
98.31
4qvnW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 10 THR H   1
SER H  20
LYS H  33
ALA H  49
THR H  52
 None
 0.75A 4qvnV-5fg9H:
36.9
4qvnW-5fg9H:
26.2		 4qvnV-5fg9H:
98.31
4qvnW-5fg9H:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 9 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.51A 4qvnY-5fg9H:
21.2
4qvnZ-5fg9H:
23.3		 4qvnY-5fg9H:
29.22
4qvnZ-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.41A 4qvpV-5fg9H:
37.2
4qvpb-5fg9H:
28.0		 4qvpV-5fg9H:
98.31
4qvpb-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 12 THR H   1
CYH H  31
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.40A 4qvpH-5fg9H:
36.5
4qvpI-5fg9H:
22.1		 4qvpH-5fg9H:
98.31
4qvpI-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 12 THR H   1
GLN H  22
CYH H  31
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.91A 4qvpH-5fg9H:
36.5
4qvpI-5fg9H:
22.1		 4qvpH-5fg9H:
98.31
4qvpI-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 12 THR H   1
SER H  20
CYH H  31
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.66A 4qvpH-5fg9H:
36.5
4qvpI-5fg9H:
22.1		 4qvpH-5fg9H:
98.31
4qvpI-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 12 THR H   1
SER H  20
GLN H  22
CYH H  31
ALA H  46
ALA H  49
THR H  52
 None
 1.01A 4qvpH-5fg9H:
36.5
4qvpI-5fg9H:
22.1		 4qvpH-5fg9H:
98.31
4qvpI-5fg9H:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.49A 4qvpK-5fg9H:
27.9
4qvpL-5fg9H:
23.1		 4qvpK-5fg9H:
29.22
4qvpL-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.43A 4qvpH-5fg9H:
36.5
4qvpN-5fg9H:
28.0		 4qvpH-5fg9H:
98.31
4qvpN-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 12 THR H   1
CYH H  31
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.37A 4qvpV-5fg9H:
37.2
4qvpW-5fg9H:
26.1		 4qvpV-5fg9H:
98.31
4qvpW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 12 THR H   1
GLN H  22
CYH H  31
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.90A 4qvpV-5fg9H:
37.2
4qvpW-5fg9H:
26.1		 4qvpV-5fg9H:
98.31
4qvpW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 12 THR H   1
SER H  20
CYH H  31
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.65A 4qvpV-5fg9H:
37.2
4qvpW-5fg9H:
26.1		 4qvpV-5fg9H:
98.31
4qvpW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 12 THR H   1
SER H  20
GLN H  22
CYH H  31
ALA H  46
ALA H  49
THR H  52
 None
 1.00A 4qvpV-5fg9H:
37.2
4qvpW-5fg9H:
26.1		 4qvpV-5fg9H:
98.31
4qvpW-5fg9H:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.48A 4qvpY-5fg9H:
21.1
4qvpZ-5fg9H:
23.3		 4qvpY-5fg9H:
29.22
4qvpZ-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.44A 4qvqV-5fg9H:
37.1
4qvqb-5fg9H:
27.9		 4qvqV-5fg9H:
98.31
4qvqb-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVQ_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
CYH H  31
LYS H  33
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.42A 4qvqH-5fg9H:
36.5
4qvqI-5fg9H:
22.0		 4qvqH-5fg9H:
98.31
4qvqI-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVQ_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
GLN H  22
CYH H  31
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.98A 4qvqH-5fg9H:
36.5
4qvqI-5fg9H:
22.0		 4qvqH-5fg9H:
98.31
4qvqI-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVQ_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
SER H  20
CYH H  31
LYS H  33
ALA H  49
THR H  52
 None
 0.70A 4qvqH-5fg9H:
36.5
4qvqI-5fg9H:
22.0		 4qvqH-5fg9H:
98.31
4qvqI-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVQ_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
SER H  20
GLN H  22
CYH H  31
ALA H  49
THR H  52
 None
 1.09A 4qvqH-5fg9H:
36.5
4qvqI-5fg9H:
22.0		 4qvqH-5fg9H:
98.31
4qvqI-5fg9H:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 9 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.50A 4qvqK-5fg9H:
27.8
4qvqL-5fg9H:
23.4		 4qvqK-5fg9H:
29.22
4qvqL-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.44A 4qvqH-5fg9H:
36.5
4qvqN-5fg9H:
27.9		 4qvqH-5fg9H:
98.31
4qvqN-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVQ_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
CYH H  31
LYS H  33
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.42A 4qvqV-5fg9H:
37.1
4qvqW-5fg9H:
26.0		 4qvqV-5fg9H:
98.31
4qvqW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVQ_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
GLN H  22
CYH H  31
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.98A 4qvqV-5fg9H:
37.1
4qvqW-5fg9H:
26.0		 4qvqV-5fg9H:
98.31
4qvqW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVQ_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
SER H  20
CYH H  31
LYS H  33
ALA H  49
THR H  52
 None
 0.69A 4qvqV-5fg9H:
37.1
4qvqW-5fg9H:
26.0		 4qvqV-5fg9H:
98.31
4qvqW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVQ_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
SER H  20
GLN H  22
CYH H  31
ALA H  49
THR H  52
 None
 1.08A 4qvqV-5fg9H:
37.1
4qvqW-5fg9H:
26.0		 4qvqV-5fg9H:
98.31
4qvqW-5fg9H:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 9 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.50A 4qvqY-5fg9H:
21.1
4qvqZ-5fg9H:
23.3		 4qvqY-5fg9H:
29.22
4qvqZ-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVV_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 10 THR H   1
THR H  21
LYS H  33
ALA H  49
THR H  52
 None
 0.35A 4qvvV-5fg9H:
37.3
4qvvb-5fg9H:
27.9		 4qvvV-5fg9H:
98.31
4qvvb-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		9 / 11 THR H   1
SER H  20
THR H  21
GLN H  22
CYH H  31
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.97A 4qvvH-5fg9H:
36.7		 4qvvH-5fg9H:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		10 / 11 THR H   1
THR H  21
GLN H  22
CYH H  31
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.87A 4qvvH-5fg9H:
36.7		 4qvvH-5fg9H:
98.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		4 / 8 THR H   1
THR H  21
LYS H  33
GLY H  47
 None
 0.43A 4qvvK-5fg9H:
27.6
4qvvL-5fg9H:
23.2		 4qvvK-5fg9H:
28.81
4qvvL-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVV_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 10 THR H   1
THR H  21
LYS H  33
ALA H  49
THR H  52
 None
 0.36A 4qvvH-5fg9H:
36.7
4qvvN-5fg9H:
27.9		 4qvvH-5fg9H:
98.31
4qvvN-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		9 / 11 THR H   1
SER H  20
THR H  21
GLN H  22
CYH H  31
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.96A 4qvvV-5fg9H:
37.3		 4qvvV-5fg9H:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		10 / 11 THR H   1
THR H  21
GLN H  22
CYH H  31
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.87A 4qvvV-5fg9H:
37.3		 4qvvV-5fg9H:
98.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		4 / 8 THR H   1
THR H  21
LYS H  33
GLY H  47
 None
 0.43A 4qvvY-5fg9H:
20.9
4qvvZ-5fg9H:
23.1		 4qvvY-5fg9H:
28.81
4qvvZ-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.40A 4qvwV-5fg9H:
37.5
4qvwb-5fg9H:
28.0		 4qvwV-5fg9H:
98.31
4qvwb-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
GLN H  22
ALA H  46
THR H  48
ALA H  49
THR H  52
 None
 0.82A 4qvwH-5fg9H:
36.8
4qvwI-5fg9H:
22.1		 4qvwH-5fg9H:
98.31
4qvwI-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
LYS H  33
ALA H  46
THR H  48
ALA H  49
THR H  52
 None
 0.23A 4qvwH-5fg9H:
36.8
4qvwI-5fg9H:
22.1		 4qvwH-5fg9H:
98.31
4qvwI-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
SER H  20
GLN H  22
ALA H  46
ALA H  49
THR H  52
 None
 0.96A 4qvwH-5fg9H:
36.8
4qvwI-5fg9H:
22.1		 4qvwH-5fg9H:
98.31
4qvwI-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
SER H  20
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.64A 4qvwH-5fg9H:
36.8
4qvwI-5fg9H:
22.1		 4qvwH-5fg9H:
98.31
4qvwI-5fg9H:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 11 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
 None
 0.41A 4qvwK-5fg9H:
20.0
4qvwL-5fg9H:
23.3		 4qvwK-5fg9H:
28.81
4qvwL-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.41A 4qvwH-5fg9H:
36.8
4qvwN-5fg9H:
28.0		 4qvwH-5fg9H:
98.31
4qvwN-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
GLN H  22
ALA H  46
THR H  48
ALA H  49
THR H  52
 None
 0.82A 4qvwV-5fg9H:
37.5
4qvwW-5fg9H:
26.1		 4qvwV-5fg9H:
98.31
4qvwW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
LYS H  33
ALA H  46
THR H  48
ALA H  49
THR H  52
 None
 0.22A 4qvwV-5fg9H:
37.5
4qvwW-5fg9H:
26.1		 4qvwV-5fg9H:
98.31
4qvwW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
SER H  20
GLN H  22
ALA H  46
ALA H  49
THR H  52
 None
 0.96A 4qvwV-5fg9H:
37.5
4qvwW-5fg9H:
26.1		 4qvwV-5fg9H:
98.31
4qvwW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
SER H  20
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.63A 4qvwV-5fg9H:
37.5
4qvwW-5fg9H:
26.1		 4qvwV-5fg9H:
98.31
4qvwW-5fg9H:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 11 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
 None
 0.41A 4qvwY-5fg9H:
21.1
4qvwZ-5fg9H:
23.2		 4qvwY-5fg9H:
28.81
4qvwZ-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 11 THR H   1
THR H  21
LYS H  33
ALA H  49
THR H  52
 None
 0.38A 4qvyV-5fg9H:
37.7
4qvyb-5fg9H:
28.0		 4qvyV-5fg9H:
98.31
4qvyb-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		9 / 11 THR H   1
SER H  20
THR H  21
GLN H  22
CYH H  31
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.94A 4qvyH-5fg9H:
37.1		 4qvyH-5fg9H:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		10 / 11 THR H   1
THR H  21
GLN H  22
CYH H  31
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.85A 4qvyH-5fg9H:
37.1		 4qvyH-5fg9H:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 11 THR H   1
THR H  21
LYS H  33
ALA H  49
THR H  52
 None
 0.38A 4qvyH-5fg9H:
37.1
4qvyN-5fg9H:
28.0		 4qvyH-5fg9H:
98.31
4qvyN-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		9 / 12 THR H   1
GLN H  22
CYH H  31
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.86A 4qvyV-5fg9H:
37.7
4qvyW-5fg9H:
26.2		 4qvyV-5fg9H:
98.31
4qvyW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 12 THR H   1
SER H  20
GLN H  22
CYH H  31
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.95A 4qvyV-5fg9H:
37.7
4qvyW-5fg9H:
26.2		 4qvyV-5fg9H:
98.31
4qvyW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.40A 4qw0V-5fg9H:
37.4
4qw0b-5fg9H:
28.0		 4qw0V-5fg9H:
98.31
4qw0b-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
GLN H  22
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.83A 4qw0H-5fg9H:
36.8
4qw0I-5fg9H:
22.0		 4qw0H-5fg9H:
98.31
4qw0I-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.29A 4qw0H-5fg9H:
36.8
4qw0I-5fg9H:
22.0		 4qw0H-5fg9H:
98.31
4qw0I-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
SER H  20
GLN H  22
ALA H  46
ALA H  49
THR H  52
 None
 1.00A 4qw0H-5fg9H:
36.8
4qw0I-5fg9H:
22.0		 4qw0H-5fg9H:
98.31
4qw0I-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
SER H  20
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.63A 4qw0H-5fg9H:
36.8
4qw0I-5fg9H:
22.0		 4qw0H-5fg9H:
98.31
4qw0I-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.42A 4qw0H-5fg9H:
36.8
4qw0N-5fg9H:
28.0		 4qw0H-5fg9H:
98.31
4qw0N-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
GLN H  22
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.83A 4qw0V-5fg9H:
37.4
4qw0W-5fg9H:
26.0		 4qw0V-5fg9H:
98.31
4qw0W-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.23A 4qw0V-5fg9H:
37.4
4qw0W-5fg9H:
26.0		 4qw0V-5fg9H:
98.31
4qw0W-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
SER H  20
GLN H  22
ALA H  46
ALA H  49
THR H  52
 None
 1.00A 4qw0V-5fg9H:
37.4
4qw0W-5fg9H:
26.0		 4qw0V-5fg9H:
98.31
4qw0W-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
SER H  20
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.62A 4qw0V-5fg9H:
37.4
4qw0W-5fg9H:
26.0		 4qw0V-5fg9H:
98.31
4qw0W-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.43A 4qw1V-5fg9H:
37.2
4qw1b-5fg9H:
28.1		 4qw1V-5fg9H:
98.31
4qw1b-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 12 THR H   1
CYH H  31
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.36A 4qw1H-5fg9H:
36.6
4qw1I-5fg9H:
22.1		 4qw1H-5fg9H:
98.31
4qw1I-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 12 THR H   1
GLN H  22
CYH H  31
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 None
 0.89A 4qw1H-5fg9H:
36.6
4qw1I-5fg9H:
22.1		 4qw1H-5fg9H:
98.31
4qw1I-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 12 THR H   1
SER H  20
GLN H  22
CYH H  31
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.97A 4qw1H-5fg9H:
36.6
4qw1I-5fg9H:
22.1		 4qw1H-5fg9H:
98.31
4qw1I-5fg9H:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.47A 4qw1K-5fg9H:
20.1
4qw1L-5fg9H:
23.4		 4qw1K-5fg9H:
28.81
4qw1L-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.43A 4qw1H-5fg9H:
36.6
4qw1N-5fg9H:
28.0		 4qw1H-5fg9H:
98.31
4qw1N-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 12 THR H   1
CYH H  31
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.35A 4qw1V-5fg9H:
37.2
4qw1W-5fg9H:
26.1		 4qw1V-5fg9H:
98.31
4qw1W-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 12 THR H   1
GLN H  22
CYH H  31
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 None
 0.89A 4qw1V-5fg9H:
37.2
4qw1W-5fg9H:
26.1		 4qw1V-5fg9H:
98.31
4qw1W-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 12 THR H   1
SER H  20
GLN H  22
CYH H  31
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.96A 4qw1V-5fg9H:
37.2
4qw1W-5fg9H:
26.1		 4qw1V-5fg9H:
98.31
4qw1W-5fg9H:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.46A 4qw1Y-5fg9H:
21.1
4qw1Z-5fg9H:
23.3		 4qw1Y-5fg9H:
28.81
4qw1Z-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.41A 4qw3V-5fg9H:
37.1
4qw3b-5fg9H:
27.9		 4qw3V-5fg9H:
98.31
4qw3b-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
GLN H  22
ALA H  46
THR H  48
ALA H  49
THR H  52
 None
 0.79A 4qw3H-5fg9H:
36.5
4qw3I-5fg9H:
21.9		 4qw3H-5fg9H:
98.31
4qw3I-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
LYS H  33
ALA H  46
THR H  48
ALA H  49
THR H  52
 None
 0.26A 4qw3H-5fg9H:
36.5
4qw3I-5fg9H:
21.9		 4qw3H-5fg9H:
98.31
4qw3I-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
SER H  20
GLN H  22
ALA H  46
ALA H  49
THR H  52
 None
 0.93A 4qw3H-5fg9H:
36.5
4qw3I-5fg9H:
21.9		 4qw3H-5fg9H:
98.31
4qw3I-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
SER H  20
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.64A 4qw3H-5fg9H:
36.5
4qw3I-5fg9H:
21.9		 4qw3H-5fg9H:
98.31
4qw3I-5fg9H:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.48A 4qw3K-5fg9H:
19.8
4qw3L-5fg9H:
23.2		 4qw3K-5fg9H:
29.22
4qw3L-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.43A 4qw3H-5fg9H:
36.5
4qw3N-5fg9H:
27.9		 4qw3H-5fg9H:
98.31
4qw3N-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
CYH H  31
LYS H  33
ALA H  46
THR H  48
ALA H  49
THR H  52
 None
 0.30A 4qw3V-5fg9H:
37.1
4qw3W-5fg9H:
25.9		 4qw3V-5fg9H:
98.31
4qw3W-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
GLN H  22
CYH H  31
ALA H  46
THR H  48
ALA H  49
THR H  52
 None
 0.86A 4qw3V-5fg9H:
37.1
4qw3W-5fg9H:
25.9		 4qw3V-5fg9H:
98.31
4qw3W-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
SER H  20
CYH H  31
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.61A 4qw3V-5fg9H:
37.1
4qw3W-5fg9H:
25.9		 4qw3V-5fg9H:
98.31
4qw3W-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
SER H  20
GLN H  22
CYH H  31
ALA H  46
ALA H  49
THR H  52
 None
 0.95A 4qw3V-5fg9H:
37.1
4qw3W-5fg9H:
25.9		 4qw3V-5fg9H:
98.31
4qw3W-5fg9H:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 10 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.48A 4qw3Y-5fg9H:
20.8
4qw3Z-5fg9H:
23.0		 4qw3Y-5fg9H:
29.22
4qw3Z-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.42A 4qwuV-5fg9H:
37.0
4qwub-5fg9H:
28.1		 4qwuV-5fg9H:
98.31
4qwub-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QWU_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 11 THR H   1
GLN H  22
CYH H  31
LYS H  33
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.92A 4qwuH-5fg9H:
36.4
4qwuI-5fg9H:
22.2		 4qwuH-5fg9H:
98.31
4qwuI-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QWU_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
SER H  20
GLN H  22
CYH H  31
LYS H  33
ALA H  49
THR H  52
 None
 1.01A 4qwuH-5fg9H:
36.4
4qwuI-5fg9H:
22.2		 4qwuH-5fg9H:
98.31
4qwuI-5fg9H:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 9 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
 None
 0.39A 4qwuK-5fg9H:
18.0
4qwuL-5fg9H:
23.2		 4qwuK-5fg9H:
29.22
4qwuL-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.43A 4qwuH-5fg9H:
36.4
4qwuN-5fg9H:
28.1		 4qwuH-5fg9H:
98.31
4qwuN-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QWU_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 11 THR H   1
GLN H  22
CYH H  31
LYS H  33
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.91A 4qwuV-5fg9H:
37.0
4qwuW-5fg9H:
26.2		 4qwuV-5fg9H:
98.31
4qwuW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QWU_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
SER H  20
GLN H  22
CYH H  31
LYS H  33
ALA H  49
THR H  52
 None
 1.00A 4qwuV-5fg9H:
37.0
4qwuW-5fg9H:
26.2		 4qwuV-5fg9H:
98.31
4qwuW-5fg9H:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 9 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
 None
 0.43A 4qwuY-5fg9H:
21.0
4qwuZ-5fg9H:
23.3		 4qwuY-5fg9H:
29.22
4qwuZ-5fg9H:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		4 / 6 ASP H  51
ALA H 115
THR H  48
THR H  -3
 None
 1.45A 4w5rA-5fg9H:
undetectable		 4w5rA-5fg9H:
14.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.41A 5bxnV-5fg9H:
36.3
5bxnb-5fg9H:
28.1		 5bxnV-5fg9H:
97.88
5bxnb-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		9 / 11 THR H   1
SER H  20
GLN H  22
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.64A 5bxnH-5fg9H:
35.9
5bxnI-5fg9H:
26.2		 5bxnH-5fg9H:
97.88
5bxnI-5fg9H:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.51A 5bxnK-5fg9H:
20.1
5bxnL-5fg9H:
23.0		 5bxnK-5fg9H:
29.22
5bxnL-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.42A 5bxnH-5fg9H:
35.9
5bxnN-5fg9H:
28.0		 5bxnH-5fg9H:
97.88
5bxnN-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		9 / 11 THR H   1
SER H  20
THR H  21
GLN H  22
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
 None
 0.64A 5bxnV-5fg9H:
36.3
5bxnW-5fg9H:
26.2		 5bxnV-5fg9H:
97.88
5bxnW-5fg9H:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.50A 5bxnY-5fg9H:
21.1
5bxnZ-5fg9H:
23.2		 5bxnY-5fg9H:
29.22
5bxnZ-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CZ7_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 9 THR H   1
THR H  21
LYS H  33
ALA H  49
THR H  52
 None
 0.37A 5cz7V-5fg9H:
37.4
5cz7b-5fg9H:
28.0		 5cz7V-5fg9H:
98.31
5cz7b-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CZ7_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
CYH H  31
LYS H  33
ALA H  46
THR H  48
ALA H  49
THR H  52
 None
 0.34A 5cz7H-5fg9H:
36.7
5cz7I-5fg9H:
22.1		 5cz7H-5fg9H:
98.31
5cz7I-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CZ7_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
GLN H  22
CYH H  31
ALA H  46
THR H  48
ALA H  49
THR H  52
 None
 0.92A 5cz7H-5fg9H:
36.7
5cz7I-5fg9H:
22.1		 5cz7H-5fg9H:
98.31
5cz7I-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CZ7_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
SER H  20
CYH H  31
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.62A 5cz7H-5fg9H:
36.7
5cz7I-5fg9H:
22.1		 5cz7H-5fg9H:
98.31
5cz7I-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CZ7_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
SER H  20
GLN H  22
CYH H  31
ALA H  46
ALA H  49
THR H  52
 None
 0.99A 5cz7H-5fg9H:
36.7
5cz7I-5fg9H:
22.1		 5cz7H-5fg9H:
98.31
5cz7I-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.44A 5cz7H-5fg9H:
36.7
5cz7N-5fg9H:
28.0		 5cz7H-5fg9H:
98.31
5cz7N-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 12 THR H   1
CYH H  31
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.33A 5cz7V-5fg9H:
37.4
5cz7W-5fg9H:
26.1		 5cz7V-5fg9H:
98.31
5cz7W-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 12 THR H   1
GLN H  22
CYH H  31
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.87A 5cz7V-5fg9H:
37.4
5cz7W-5fg9H:
26.1		 5cz7V-5fg9H:
98.31
5cz7W-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 12 THR H   1
SER H  20
CYH H  31
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.63A 5cz7V-5fg9H:
37.4
5cz7W-5fg9H:
26.1		 5cz7V-5fg9H:
98.31
5cz7W-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 12 THR H   1
SER H  20
GLN H  22
CYH H  31
ALA H  46
ALA H  49
THR H  52
 None
 0.98A 5cz7V-5fg9H:
37.4
5cz7W-5fg9H:
26.1		 5cz7V-5fg9H:
98.31
5cz7W-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.39A 5d0xV-5fg9H:
37.5
5d0xb-5fg9H:
28.0		 5d0xV-5fg9H:
98.31
5d0xb-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 12 THR H   1
SER H  20
THR H  21
CYH H  31
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.56A 5d0xH-5fg9H:
36.8
5d0xI-5fg9H:
22.0		 5d0xH-5fg9H:
98.31
5d0xI-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 12 THR H   1
SER H  20
THR H  21
GLN H  22
CYH H  31
ALA H  46
ALA H  49
THR H  52
 None
 0.93A 5d0xH-5fg9H:
36.8
5d0xI-5fg9H:
22.0		 5d0xH-5fg9H:
98.31
5d0xI-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 12 THR H   1
THR H  21
CYH H  31
LYS H  33
ALA H  46
THR H  48
ALA H  49
THR H  52
 None
 0.25A 5d0xH-5fg9H:
36.8
5d0xI-5fg9H:
22.0		 5d0xH-5fg9H:
98.31
5d0xI-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 12 THR H   1
THR H  21
GLN H  22
CYH H  31
ALA H  46
THR H  48
ALA H  49
THR H  52
 None
 0.86A 5d0xH-5fg9H:
36.8
5d0xI-5fg9H:
22.0		 5d0xH-5fg9H:
98.31
5d0xI-5fg9H:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 9 THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.50A 5d0xK-5fg9H:
20.0
5d0xL-5fg9H:
23.3		 5d0xK-5fg9H:
29.34
5d0xL-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.43A 5d0xH-5fg9H:
36.8
5d0xN-5fg9H:
28.0		 5d0xH-5fg9H:
98.31
5d0xN-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 11 THR H   1
SER H  20
THR H  21
CYH H  31
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.55A 5d0xV-5fg9H:
37.5		 5d0xV-5fg9H:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 11 THR H   1
SER H  20
THR H  21
GLN H  22
CYH H  31
ALA H  46
ALA H  49
THR H  52
 None
 0.93A 5d0xV-5fg9H:
37.5		 5d0xV-5fg9H:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		9 / 11 THR H   1
THR H  21
CYH H  31
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.28A 5d0xV-5fg9H:
37.5		 5d0xV-5fg9H:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		9 / 11 THR H   1
THR H  21
GLN H  22
CYH H  31
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.82A 5d0xV-5fg9H:
37.5		 5d0xV-5fg9H:
98.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 9 THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.50A 5d0xY-5fg9H:
21.0
5d0xZ-5fg9H:
23.1		 5d0xY-5fg9H:
29.34
5d0xZ-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5F_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 11 THR H   1
THR H  21
LYS H  33
ALA H  49
THR H  52
 None
 0.37A 5l5fV-5fg9H:
37.3
5l5fb-5fg9H:
28.0		 5l5fV-5fg9H:
98.31
5l5fb-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 12 THR H   1
CYH H  31
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.37A 5l5fH-5fg9H:
36.6
5l5fI-5fg9H:
26.1		 5l5fH-5fg9H:
98.31
5l5fI-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 12 THR H   1
GLN H  22
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.68A 5l5fH-5fg9H:
36.6
5l5fI-5fg9H:
26.1		 5l5fH-5fg9H:
98.31
5l5fI-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 12 THR H   1
SER H  20
CYH H  31
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.66A 5l5fH-5fg9H:
36.6
5l5fI-5fg9H:
26.1		 5l5fH-5fg9H:
98.31
5l5fI-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 12 THR H   1
SER H  20
GLN H  22
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.77A 5l5fH-5fg9H:
36.6
5l5fI-5fg9H:
26.1		 5l5fH-5fg9H:
98.31
5l5fI-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5F_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 11 THR H   1
THR H  21
LYS H  33
ALA H  49
THR H  52
 None
 0.38A 5l5fH-5fg9H:
36.6
5l5fN-5fg9H:
28.0		 5l5fH-5fg9H:
98.31
5l5fN-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 12 THR H   1
CYH H  31
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.37A 5l5fV-5fg9H:
37.3
5l5fW-5fg9H:
26.1		 5l5fV-5fg9H:
98.31
5l5fW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		8 / 12 THR H   1
GLN H  22
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.68A 5l5fV-5fg9H:
37.3
5l5fW-5fg9H:
26.1		 5l5fV-5fg9H:
98.31
5l5fW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 12 THR H   1
SER H  20
CYH H  31
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.66A 5l5fV-5fg9H:
37.3
5l5fW-5fg9H:
26.1		 5l5fV-5fg9H:
98.31
5l5fW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 12 THR H   1
SER H  20
GLN H  22
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.76A 5l5fV-5fg9H:
37.3
5l5fW-5fg9H:
26.1		 5l5fV-5fg9H:
98.31
5l5fW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 12 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.43A 5l5zV-5fg9H:
37.2
5l5zb-5fg9H:
27.9		 5l5zV-5fg9H:
98.31
5l5zb-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		9 / 12 THR H   1
SER H  20
THR H  21
GLN H  22
CYH H  31
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.75A 5l5zH-5fg9H:
35.8
5l5zI-5fg9H:
22.2		 5l5zH-5fg9H:
98.31
5l5zI-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		9 / 12 THR H   1
THR H  21
GLN H  22
CYH H  31
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 None
 0.69A 5l5zH-5fg9H:
35.8
5l5zI-5fg9H:
22.2		 5l5zH-5fg9H:
98.31
5l5zI-5fg9H:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 9 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.63A 5l5zK-5fg9H:
28.1
5l5zL-5fg9H:
23.1		 5l5zK-5fg9H:
29.54
5l5zL-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 12 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.45A 5l5zH-5fg9H:
36.5
5l5zN-5fg9H:
27.9		 5l5zH-5fg9H:
98.31
5l5zN-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		9 / 12 THR H   1
SER H  20
THR H  21
GLN H  22
CYH H  31
LYS H  33
ALA H  46
ALA H  49
THR H  52
 None
 0.75A 5l5zV-5fg9H:
37.2
5l5zW-5fg9H:
26.2		 5l5zV-5fg9H:
98.31
5l5zW-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		9 / 12 THR H   1
THR H  21
GLN H  22
CYH H  31
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 None
 0.68A 5l5zV-5fg9H:
37.2
5l5zW-5fg9H:
26.2		 5l5zV-5fg9H:
98.31
5l5zW-5fg9H:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 9 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.63A 5l5zY-5fg9H:
28.1
5l5zZ-5fg9H:
23.2		 5l5zY-5fg9H:
29.54
5l5zZ-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.41A 5l66V-5fg9H:
37.0
5l66b-5fg9H:
27.9		 5l66V-5fg9H:
98.31
5l66b-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		9 / 12 THR H   1
GLN H  22
CYH H  31
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.78A 5l66H-5fg9H:
36.4
5l66I-5fg9H:
22.1		 5l66H-5fg9H:
98.31
5l66I-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 12 THR H   1
SER H  20
GLN H  22
CYH H  31
LYS H  33
ALA H  46
THR H  52
 None
 0.81A 5l66H-5fg9H:
36.4
5l66I-5fg9H:
22.1		 5l66H-5fg9H:
98.31
5l66I-5fg9H:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 10 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
 None
 0.52A 5l66K-5fg9H:
13.5
5l66L-5fg9H:
23.3		 5l66K-5fg9H:
28.27
5l66L-5fg9H:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.44A 5l66H-5fg9H:
36.4
5l66N-5fg9H:
27.9		 5l66H-5fg9H:
98.31
5l66N-5fg9H:
29.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		9 / 12 THR H   1
GLN H  22
CYH H  31
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.79A 5l66V-5fg9H:
37.0
5l66W-5fg9H:
26.1		 5l66V-5fg9H:
98.31
5l66W-5fg9H:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 12 THR H   1
SER H  20
GLN H  22
CYH H  31
LYS H  33
ALA H  46
THR H  52
 None
 0.81A 5l66V-5fg9H:
37.0
5l66W-5fg9H:
26.1		 5l66V-5fg9H:
98.31
5l66W-5fg9H:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 10 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
 None
 0.52A 5l66Y-5fg9H:
28.2
5l66Z-5fg9H:
23.2		 5l66Y-5fg9H:
28.27
5l66Z-5fg9H:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 12 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.48A 5lf3b-5fg9H:
28.1		 5lf3b-5fg9H:
28.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 10 THR H   1
THR H  21
CYH H  31
ALA H  46
GLY H  47
ALA H  49
THR H  52
 None
 0.47A 5lf3H-5fg9H:
34.1
5lf3I-5fg9H:
26.3		 5lf3H-5fg9H:
55.23
5lf3I-5fg9H:
25.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
 None
 0.48A 5lf3K-5fg9H:
28.3
5lf3L-5fg9H:
24.7		 5lf3K-5fg9H:
28.27
5lf3L-5fg9H:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 12 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.49A 5lf3N-5fg9H:
28.1		 5lf3N-5fg9H:
28.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 10 THR H   1
THR H  21
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
 None
 0.36A 5lf3V-5fg9H:
34.1
5lf3W-5fg9H:
26.4		 5lf3V-5fg9H:
55.23
5lf3W-5fg9H:
25.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
 None
 0.49A 5lf3Y-5fg9H:
28.3
5lf3Z-5fg9H:
24.7		 5lf3Y-5fg9H:
28.27
5lf3Z-5fg9H:
24.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 12 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.48A 5lf7V-5fg9H:
34.1
5lf7b-5fg9H:
28.2		 5lf7V-5fg9H:
55.23
5lf7b-5fg9H:
28.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
THR H  21
CYH H  31
ALA H  46
GLY H  47
ALA H  49
THR H  52
 None
 0.40A 5lf7H-5fg9H:
34.1
5lf7I-5fg9H:
26.3		 5lf7H-5fg9H:
55.23
5lf7I-5fg9H:
25.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
 None
 0.48A 5lf7K-5fg9H:
28.3
5lf7L-5fg9H:
24.7		 5lf7K-5fg9H:
28.27
5lf7L-5fg9H:
24.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 12 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.47A 5lf7H-5fg9H:
34.1
5lf7N-5fg9H:
28.2		 5lf7H-5fg9H:
55.23
5lf7N-5fg9H:
28.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 11 THR H   1
THR H  21
CYH H  31
ALA H  46
GLY H  47
ALA H  49
THR H  52
 None
 0.38A 5lf7V-5fg9H:
34.1
5lf7W-5fg9H:
26.4		 5lf7V-5fg9H:
55.23
5lf7W-5fg9H:
25.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 11 THR H   1
THR H  21
LYS H  33
GLY H  47
ALA H  49
 None
 0.47A 5lf7Y-5fg9H:
28.4
5lf7Z-5fg9H:
24.7		 5lf7Y-5fg9H:
28.27
5lf7Z-5fg9H:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OS7_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		3 / 3 HIS H 109
SER H 108
LYS H   7
 None
 1.23A 5os7A-5fg9H:
undetectable		 5os7A-5fg9H:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSG_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 10 LEU H 154
VAL H  13
VAL H   4
GLY H   5
LEU H 146
 None
 1.48A 6bsgA-5fg9H:
undetectable		 6bsgA-5fg9H:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSG_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 10 LEU H 154
VAL H  13
VAL H   4
TYR H 124
LEU H 146
 None
 0.92A 6bsgA-5fg9H:
undetectable		 6bsgA-5fg9H:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 10 LEU H 154
VAL H  13
VAL H   4
GLY H   5
LEU H 146
 None
 1.47A 6bsiA-5fg9H:
undetectable		 6bsiA-5fg9H:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 10 LEU H 154
VAL H  13
VAL H   4
TYR H 124
LEU H 146
 None
 0.99A 6bsiA-5fg9H:
undetectable		 6bsiA-5fg9H:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSJ_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 10 LEU H 154
VAL H  13
VAL H   4
GLY H   5
LEU H 146
 None
 1.48A 6bsjA-5fg9H:
undetectable		 6bsjA-5fg9H:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSJ_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		5 / 10 LEU H 154
VAL H  13
VAL H   4
TYR H 124
LEU H 146
 None
 0.89A 6bsjA-5fg9H:
undetectable		 6bsjA-5fg9H:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GMD_B_ACTB402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		3 / 3 HIS H 109
SER H 108
LYS H   7
 None
 1.23A 6gmdB-5fg9H:
undetectable		 6gmdB-5fg9H:
18.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 12 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.43A 6hwdV-5fg9H:
37.1
6hwdb-5fg9H:
28.0		 6hwdV-5fg9H:
94.05
6hwdb-5fg9H:
19.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		10 / 12 THR H   1
SER H  20
ALA H  27
CYH H  31
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.46A 6hwdH-5fg9H:
36.5
6hwdI-5fg9H:
22.1		 6hwdH-5fg9H:
94.05
6hwdI-5fg9H:
19.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		10 / 12 THR H   1
SER H  20
GLN H  22
ALA H  27
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.73A 6hwdH-5fg9H:
36.5
6hwdI-5fg9H:
22.1		 6hwdH-5fg9H:
94.05
6hwdI-5fg9H:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.52A 6hwdK-5fg9H:
27.8
6hwdL-5fg9H:
23.5		 6hwdK-5fg9H:
21.25
6hwdL-5fg9H:
15.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		7 / 12 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
THR H  52
 None
 0.43A 6hwdH-5fg9H:
36.5
6hwdN-5fg9H:
28.0		 6hwdH-5fg9H:
94.05
6hwdN-5fg9H:
19.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		10 / 11 THR H   1
SER H  20
ALA H  27
CYH H  31
LYS H  33
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.45A 6hwdV-5fg9H:
37.1		 6hwdV-5fg9H:
94.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		9 / 11 THR H   1
SER H  20
GLN H  22
ALA H  27
ALA H  46
GLY H  47
THR H  48
ALA H  49
THR H  52
 None
 0.74A 6hwdV-5fg9H:
37.1		 6hwdV-5fg9H:
94.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fg9 PROTEASOME SUBUNIT
BETA TYPE-2
(Saccharomyces
cerevisiae) 		6 / 11 THR H   1
THR H  21
ALA H  27
LYS H  33
GLY H  47
ALA H  49
 None
 0.52A 6hwdY-5fg9H:
21.2
6hwdZ-5fg9H:
23.4		 6hwdY-5fg9H:
21.25
6hwdZ-5fg9H:
15.25