SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fhi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 5fhi GLUTATHIONE
S-TRANSFERASE,
PUTATIVE
(Aspergillus
fumigatus) 		4 / 5 GLU A  87
THR A  78
LEU A  80
LEU A  81
 None
 1.20A 1u18B-5fhiA:
undetectable		 1u18B-5fhiA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 5fhi GLUTATHIONE
S-TRANSFERASE,
PUTATIVE
(Aspergillus
fumigatus) 		4 / 7 THR A 200
ASP A  12
SER A 165
LEU A 153
 None
 1.06A 2hdnE-5fhiA:
undetectable
2hdnF-5fhiA:
undetectable
2hdnH-5fhiA:
undetectable		 2hdnE-5fhiA:
8.97
2hdnF-5fhiA:
20.96
2hdnH-5fhiA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 5fhi GLUTATHIONE
S-TRANSFERASE,
PUTATIVE
(Aspergillus
fumigatus) 		3 / 3 ASN A 180
ASP A 136
ARG A 121
 None
 0.83A 3k13C-5fhiA:
undetectable		 3k13C-5fhiA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 5fhi GLUTATHIONE
S-TRANSFERASE,
PUTATIVE
(Aspergillus
fumigatus) 		3 / 3 PRO A 215
TYR A 119
GLY A 115
 None
 0.71A 4g2zA-5fhiA:
undetectable		 4g2zA-5fhiA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 5fhi GLUTATHIONE
S-TRANSFERASE,
PUTATIVE
(Aspergillus
fumigatus) 		5 / 12 LEU A 158
GLY A 162
SER A 154
LEU A 153
VAL A 190
 None
 0.81A 5twjA-5fhiA:
undetectable		 5twjA-5fhiA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_C_SAMC201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 5fhi GLUTATHIONE
S-TRANSFERASE,
PUTATIVE
(Aspergillus
fumigatus) 		5 / 12 LEU A 158
GLY A 162
SER A 154
LEU A 153
VAL A 190
 None
 0.82A 5twjC-5fhiA:
undetectable		 5twjC-5fhiA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_A_SAMA505_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 5fhi GLUTATHIONE
S-TRANSFERASE,
PUTATIVE
(Aspergillus
fumigatus) 		3 / 3 ILE A  67
ASN A  99
CYH A 160
 None
GSH  A 301 (-3.2A)
None
 0.83A 6bp4A-5fhiA:
undetectable		 6bp4A-5fhiA:
21.78