SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fhy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CET_A_CLQA1001_0
(PROTEIN (L-LACTATE
DEHYDROGENASE))		 5fhy B-TYPE FLAGELLAR
HOOK-ASSOCIATED
PROTEIN 2
(Pseudomonas
aeruginosa) 		5 / 9 VAL A 255
GLY A 254
ASP A 253
TYR A  95
ALA A  90
 None
 0.93A 1cetA-5fhyA:
undetectable		 1cetA-5fhyA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 5fhy B-TYPE FLAGELLAR
HOOK-ASSOCIATED
PROTEIN 2
(Pseudomonas
aeruginosa) 		3 / 3 PRO A 215
THR A 213
PRO A 211
 None
 0.82A 2d55C-5fhyA:
undetectable		 2d55C-5fhyA:
4.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_C_ACTC1113_0
(BLR5658 PROTEIN)		 5fhy B-TYPE FLAGELLAR
HOOK-ASSOCIATED
PROTEIN 2
(Pseudomonas
aeruginosa) 		4 / 4 ASN A 231
ALA A 244
GLY A 184
THR A 183
 None
 1.24A 4bboC-5fhyA:
undetectable		 4bboC-5fhyA:
19.87