SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fic'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_0
(FTSJ)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		5 / 12 ALA A 522
GLY A 243
TRP A 242
LEU A 205
LEU A 259
 None
 0.81A 1eizA-5ficA:
undetectable		 1eizA-5ficA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_0
(FTSJ)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		5 / 12 ALA A 522
GLY A 243
TRP A 242
LEU A 205
LEU A 259
 None
 0.83A 1ej0A-5ficA:
undetectable		 1ej0A-5ficA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1001_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		5 / 12 PHE A 478
PHE A 453
PRO A 426
TYR A 438
ALA A 475
 None
 1.14A 1fm4A-5ficA:
undetectable		 1fm4A-5ficA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		3 / 3 ASP A 276
HIS A 317
HIS A 206
 ZN  A 702 (-2.4A)
PO4  A 709 (-4.0A)
ZN  A 701 ( 3.2A)
 0.60A 1oe1A-5ficA:
undetectable		 1oe1A-5ficA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		3 / 3 ASP A 276
HIS A 317
HIS A 206
 ZN  A 702 (-2.4A)
PO4  A 709 (-4.0A)
ZN  A 701 ( 3.2A)
 0.60A 1oe3A-5ficA:
undetectable		 1oe3A-5ficA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		5 / 12 GLY A 422
HIS A 423
HIS A 455
THR A 203
ALA A 480
 None
ZN  A 702 (-3.2A)
ZN  A 702 ( 3.1A)
None
None
 1.00A 1utdL-5ficA:
undetectable
1utdM-5ficA:
undetectable		 1utdL-5ficA:
9.11
1utdM-5ficA:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 7 LEU A 479
PRO A 425
GLY A 315
ASP A 276
 None
None
None
ZN  A 702 (-2.4A)
 0.90A 2ddwB-5ficA:
undetectable		 2ddwB-5ficA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_2
(ESTROGEN RECEPTOR)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 4 LEU A 470
THR A 469
ILE A 463
HIS A 552
 None
 0.97A 2jfaB-5ficA:
undetectable		 2jfaB-5ficA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		3 / 3 ASP A 276
HIS A 317
HIS A 206
 ZN  A 702 (-2.4A)
PO4  A 709 (-4.0A)
ZN  A 701 ( 3.2A)
 0.61A 2xxgA-5ficA:
undetectable		 2xxgA-5ficA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		3 / 3 ASP A 276
HIS A 317
HIS A 206
 ZN  A 702 (-2.4A)
PO4  A 709 (-4.0A)
ZN  A 701 ( 3.2A)
 0.62A 2xxgC-5ficA:
undetectable		 2xxgC-5ficA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 7 TYR A 438
SER A 434
GLN A 451
ILE A 440
 None
 1.28A 2xz5A-5ficA:
undetectable
2xz5B-5ficA:
undetectable		 2xz5A-5ficA:
17.84
2xz5B-5ficA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_D_CLMD221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		5 / 12 SER A 197
PHE A 452
VAL A 199
ALA A 449
HIS A 507
 None
 1.14A 3u9fD-5ficA:
undetectable
3u9fE-5ficA:
undetectable		 3u9fD-5ficA:
17.51
3u9fE-5ficA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_G_CLMG221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		5 / 12 SER A 197
PHE A 452
VAL A 199
ALA A 449
HIS A 507
 None
 1.22A 3u9fG-5ficA:
undetectable
3u9fH-5ficA:
undetectable		 3u9fG-5ficA:
17.51
3u9fH-5ficA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		3 / 3 GLN A 451
PHE A 464
TYR A 437
 None
 0.79A 3ucjB-5ficA:
undetectable		 3ucjB-5ficA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		3 / 3 GLN A 451
PHE A 464
TYR A 437
 None
 0.76A 3ucjA-5ficA:
undetectable		 3ucjA-5ficA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB501_1
(HEMOLYTIC LECTIN
CEL-III)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 5 ASP A 221
SER A 229
GLY A 228
ASP A 127
 None
 1.28A 3w9tB-5ficA:
undetectable		 3w9tB-5ficA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1003_1
(HEMOLYTIC LECTIN
CEL-III)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 5 ASP A 221
SER A 229
GLY A 228
ASP A 127
 None
 1.29A 3w9tC-5ficA:
undetectable		 3w9tC-5ficA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD501_1
(HEMOLYTIC LECTIN
CEL-III)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 5 ASP A 221
SER A 229
GLY A 228
ASP A 127
 None
 1.29A 3w9tD-5ficA:
undetectable		 3w9tD-5ficA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		5 / 12 TRP A 283
GLU A 210
HIS A 209
ASP A 289
ASP A 281
 None
 1.41A 3ximD-5ficA:
3.1		 3ximD-5ficA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		3 / 3 PHE A 268
VAL A 495
GLU A 513
 None
 0.74A 4fvqA-5ficA:
undetectable		 4fvqA-5ficA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 8 ASP A 499
ALA A 194
TYR A 502
SER A 506
 None
 1.07A 4l7iB-5ficA:
undetectable		 4l7iB-5ficA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 5 GLN A 130
SER A 131
ASP A 221
ASP A 216
 None
 1.35A 4qtuB-5ficA:
undetectable		 4qtuB-5ficA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 5 GLN A 130
SER A 131
ASP A 221
ASP A 216
 None
 1.36A 4qtuD-5ficA:
undetectable		 4qtuD-5ficA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_2
(CYTOCHROME P450 2D6)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		3 / 3 GLU A 460
ILE A 424
ALA A 477
 None
 0.65A 4wnwB-5ficA:
undetectable		 4wnwB-5ficA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 5 ALA A 342
HIS A 455
PRO A 278
PHE A 325
 None
ZN  A 702 ( 3.1A)
None
None
 1.42A 4ze2A-5ficA:
undetectable		 4ze2A-5ficA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		5 / 12 ILE A 440
ALA A 477
LEU A 479
GLY A 454
THR A 274
 None
 0.95A 5igtA-5ficA:
undetectable		 5igtA-5ficA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 4 HIS A 457
HIS A 317
HIS A 280
HIS A 206
 ZN  A 701 ( 3.2A)
PO4  A 709 (-4.0A)
PO4  A 709 (-3.8A)
ZN  A 701 ( 3.2A)
 0.86A 5mhwA-5ficA:
undetectable		 5mhwA-5ficA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 4 HIS A 457
HIS A 317
HIS A 280
HIS A 206
 ZN  A 701 ( 3.2A)
PO4  A 709 (-4.0A)
PO4  A 709 (-3.8A)
ZN  A 701 ( 3.2A)
 0.86A 5mhxA-5ficA:
undetectable		 5mhxA-5ficA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 4 HIS A 457
HIS A 317
HIS A 280
HIS A 206
 ZN  A 701 ( 3.2A)
PO4  A 709 (-4.0A)
PO4  A 709 (-3.8A)
ZN  A 701 ( 3.2A)
 0.86A 5mhyA-5ficA:
undetectable		 5mhyA-5ficA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 4 HIS A 457
HIS A 317
HIS A 280
HIS A 206
 ZN  A 701 ( 3.2A)
PO4  A 709 (-4.0A)
PO4  A 709 (-3.8A)
ZN  A 701 ( 3.2A)
 0.86A 5mhzA-5ficA:
undetectable		 5mhzA-5ficA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 4 HIS A 457
HIS A 317
HIS A 280
HIS A 206
 ZN  A 701 ( 3.2A)
PO4  A 709 (-4.0A)
PO4  A 709 (-3.8A)
ZN  A 701 ( 3.2A)
 0.86A 5mi1A-5ficA:
undetectable		 5mi1A-5ficA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 4 HIS A 457
HIS A 317
HIS A 280
HIS A 206
 ZN  A 701 ( 3.2A)
PO4  A 709 (-4.0A)
PO4  A 709 (-3.8A)
ZN  A 701 ( 3.2A)
 0.86A 5mi2A-5ficA:
undetectable		 5mi2A-5ficA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 4 HIS A 457
HIS A 317
HIS A 280
HIS A 206
 ZN  A 701 ( 3.2A)
PO4  A 709 (-4.0A)
PO4  A 709 (-3.8A)
ZN  A 701 ( 3.2A)
 0.87A 5miaA-5ficA:
undetectable		 5miaA-5ficA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 4 HIS A 457
HIS A 317
HIS A 280
HIS A 206
 ZN  A 701 ( 3.2A)
PO4  A 709 (-4.0A)
PO4  A 709 (-3.8A)
ZN  A 701 ( 3.2A)
 0.87A 5mibA-5ficA:
undetectable		 5mibA-5ficA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 4 HIS A 457
HIS A 317
HIS A 280
HIS A 206
 ZN  A 701 ( 3.2A)
PO4  A 709 (-4.0A)
PO4  A 709 (-3.8A)
ZN  A 701 ( 3.2A)
 0.86A 5micA-5ficA:
undetectable		 5micA-5ficA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 4 HIS A 457
HIS A 317
HIS A 280
HIS A 206
 ZN  A 701 ( 3.2A)
PO4  A 709 (-4.0A)
PO4  A 709 (-3.8A)
ZN  A 701 ( 3.2A)
 0.86A 5midA-5ficA:
undetectable		 5midA-5ficA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 4 HIS A 457
HIS A 317
HIS A 280
HIS A 206
 ZN  A 701 ( 3.2A)
PO4  A 709 (-4.0A)
PO4  A 709 (-3.8A)
ZN  A 701 ( 3.2A)
 0.87A 5mieA-5ficA:
undetectable		 5mieA-5ficA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_1
(SCRFP-TAG,GP41)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		5 / 12 LEU A 517
GLY A 492
GLU A 256
LEU A 259
LEU A 262
 None
 1.24A 5nwvA-5ficA:
undetectable		 5nwvA-5ficA:
5.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 6 ARG A 227
THR A 215
ASP A 216
ASP A 221
 None
 1.00A 5tdzA-5ficA:
undetectable		 5tdzA-5ficA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 4 LEU A 351
LEU A 367
SER A 377
ALA A 366
 None
 1.04A 5uunA-5ficA:
undetectable		 5uunA-5ficA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		3 / 3 ASP A 208
ARG A 226
ASP A 289
 None
 0.87A 5zvgA-5ficA:
undetectable		 5zvgA-5ficA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		3 / 3 ASP A 208
ARG A 226
ASP A 289
 None
 0.88A 5zvgB-5ficA:
undetectable		 5zvgB-5ficA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_2
(TUBULIN BETA CHAIN)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 5 LEU A 259
THR A 203
ARG A 198
ARG A 533
 None
None
PO4  A 710 (-3.5A)
None
 1.26A 6ew0B-5ficA:
undetectable		 6ew0B-5ficA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_2
(TUBULIN BETA CHAIN)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 5 LEU A 259
THR A 203
ARG A 198
ARG A 533
 None
None
PO4  A 710 (-3.5A)
None
 1.26A 6ew0D-5ficA:
undetectable		 6ew0D-5ficA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_2
(TUBULIN BETA CHAIN)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 5 LEU A 259
THR A 203
ARG A 198
ARG A 533
 None
None
PO4  A 710 (-3.5A)
None
 1.26A 6ew0H-5ficA:
undetectable		 6ew0H-5ficA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_2
(TUBULIN BETA CHAIN)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		4 / 5 LEU A 259
THR A 203
ARG A 198
ARG A 533
 None
None
PO4  A 710 (-3.5A)
None
 1.26A 6ew0I-5ficA:
undetectable		 6ew0I-5ficA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_1
(-)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		5 / 12 VAL A 314
ASN A 381
ARG A 287
PRO A 326
GLY A 324
 None
 1.13A 6gnfA-5ficA:
undetectable		 6gnfA-5ficA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_2
(-)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		5 / 12 VAL A 314
ASN A 381
ARG A 287
PRO A 326
GLY A 324
 None
 1.14A 6gnfC-5ficA:
undetectable		 6gnfC-5ficA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 5fic SPHINGOMYELIN
PHOSPHODIESTERASE
(Mus
musculus) 		5 / 9 ILE A 424
GLY A 315
GLY A 362
TYR A 340
ASN A 381
 None
 1.31A 6nm4B-5ficA:
undetectable		 6nm4B-5ficA:
16.07