SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fim'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 5fim YGAU
(Escherichia
coli) 		4 / 7 GLY A  11
GLN A 142
MET A 131
ILE A  80
 None
 1.07A 1rxcF-5fimA:
undetectable		 1rxcF-5fimA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 5fim YGAU
(Escherichia
coli) 		4 / 7 GLY A  11
GLN A 142
MET A 131
ILE A  80
 None
 1.06A 1rxcL-5fimA:
undetectable		 1rxcL-5fimA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_0
(AMINOMETHYLTRANSFERA
SE)		 5fim YGAU
(Escherichia
coli) 		5 / 12 THR A 106
LEU A 107
ILE A 110
VAL A 114
LEU A 132
 None
 1.07A 1wsvA-5fimA:
undetectable		 1wsvA-5fimA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)		 5fim YGAU
(Escherichia
coli) 		5 / 12 THR A 106
LEU A 107
ILE A 110
VAL A 114
LEU A 132
 None
 1.12A 1wsvB-5fimA:
undetectable		 1wsvB-5fimA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 5fim YGAU
(Escherichia
coli) 		4 / 6 ILE A  48
LYS A  54
ILE A  80
HIS A  34
 None
 1.21A 3eteA-5fimA:
undetectable
3eteE-5fimA:
undetectable		 3eteA-5fimA:
17.92
3eteE-5fimA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 5fim YGAU
(Escherichia
coli) 		4 / 6 GLY A  11
GLN A 142
MET A 131
ILE A  80
 None
 1.07A 3kvvA-5fimA:
undetectable		 3kvvA-5fimA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 5fim YGAU
(Escherichia
coli) 		4 / 6 GLY A  11
GLN A 142
MET A 131
ILE A  80
 None
 1.07A 3kvvB-5fimA:
undetectable		 3kvvB-5fimA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 5fim YGAU
(Escherichia
coli) 		4 / 6 GLY A  11
GLN A 142
MET A 131
ILE A  80
 None
 1.07A 3kvvC-5fimA:
undetectable		 3kvvC-5fimA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 5fim YGAU
(Escherichia
coli) 		4 / 6 GLY A  11
GLN A 142
MET A 131
ILE A  80
 None
 1.10A 3kvvF-5fimA:
undetectable		 3kvvF-5fimA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 5fim YGAU
(Escherichia
coli) 		4 / 6 GLY A  11
GLN A 142
MET A 131
ILE A  80
 None
 1.13A 4e1vF-5fimA:
undetectable		 4e1vF-5fimA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5fim YGAU
(Escherichia
coli) 		5 / 12 ILE A  50
GLY A  53
PHE A   6
ALA A  55
ALA A  28
 None
 0.90A 5n0oB-5fimA:
undetectable		 5n0oB-5fimA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5fim YGAU
(Escherichia
coli) 		5 / 12 ILE A  50
GLY A  53
PHE A   6
ALA A  55
ALA A  28
 None
 0.91A 5n0tB-5fimA:
undetectable		 5n0tB-5fimA:
17.05