SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fip'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 5fip GH5 CELLULASE
(unidentified) 		3 / 3 ALA A 100
VAL A 353
TRP A 108
 None
 0.89A 1bdwA-5fipA:
undetectable
1bdwB-5fipA:
undetectable		 1bdwA-5fipA:
7.21
1bdwB-5fipA:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 5fip GH5 CELLULASE
(unidentified) 		4 / 6 ALA A 339
SER A 264
ARG A 114
LEU A 330
 None
 1.14A 1gahA-5fipA:
undetectable		 1gahA-5fipA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 5fip GH5 CELLULASE
(unidentified) 		3 / 4 LYS A 173
ALA A 176
MET A 224
 EDO  A1390 (-3.3A)
None
None
 1.03A 1hk3A-5fipA:
undetectable		 1hk3A-5fipA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 5fip GH5 CELLULASE
(unidentified) 		4 / 8 PHE A 101
SER A  85
ARG A 114
ALA A 141
 None
 1.19A 1rqpA-5fipA:
undetectable		 1rqpA-5fipA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U1J_A_C2FA773_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 5fip GH5 CELLULASE
(unidentified) 		4 / 8 ARG A 367
LYS A 371
ASN A 144
SER A 105
 None
None
EDO  A1392 (-3.9A)
None
 1.26A 1u1jA-5fipA:
9.1		 1u1jA-5fipA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 5fip GH5 CELLULASE
(unidentified) 		5 / 12 ASN A 191
GLU A 192
HIS A 259
GLU A 294
TRP A 328
 None
None
None
None
IPA  A1394 (-4.3A)
 0.57A 2v3dA-5fipA:
16.3		 2v3dA-5fipA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 5fip GH5 CELLULASE
(unidentified) 		3 / 3 TYR A 261
GLU A 192
ASN A 156
 None
 0.87A 2y7hC-5fipA:
undetectable		 2y7hC-5fipA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 5fip GH5 CELLULASE
(unidentified) 		5 / 12 ARG A 114
GLU A 188
TYR A 261
ASN A 191
HIS A 153
 None
 1.45A 3bjmB-5fipA:
undetectable		 3bjmB-5fipA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LK0_D_Z80D92_1
(PROTEIN S100-B)		 5fip GH5 CELLULASE
(unidentified) 		3 / 3 HIS A 153
PHE A 171
PHE A 172
 None
 0.52A 3lk0D-5fipA:
undetectable		 3lk0D-5fipA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RLB_B_VIBB187_1
(THIT)		 5fip GH5 CELLULASE
(unidentified) 		5 / 12 ILE A  79
TYR A 147
GLY A  83
VAL A  51
ASN A 111
 None
 1.21A 3rlbB-5fipA:
undetectable		 3rlbB-5fipA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 5fip GH5 CELLULASE
(unidentified) 		5 / 12 ARG A 114
GLU A 188
TYR A 261
ASN A 191
HIS A 153
 None
 1.48A 3w2tA-5fipA:
undetectable		 3w2tA-5fipA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 5fip GH5 CELLULASE
(unidentified) 		5 / 12 ARG A 114
GLU A 188
TYR A 261
ASN A 191
HIS A 153
 None
 1.43A 3w2tB-5fipA:
undetectable		 3w2tB-5fipA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4APJ_A_ACTA1635_0
(ANGIOTENSIN-CONVERTI
NG ENZYME
BRADYKININ-POTENTIAT
ING PEPTIDE B)		 5fip GH5 CELLULASE
(unidentified) 		4 / 6 HIS A 259
GLU A 294
ASP A 151
SER A  85
 None
 1.07A 4apjA-5fipA:
undetectable
4apjP-5fipA:
undetectable		 4apjA-5fipA:
20.00
4apjP-5fipA:
3.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5fip GH5 CELLULASE
(unidentified) 		5 / 12 GLU A 310
LEU A 318
GLU A 299
ALA A 258
ILE A 280
 PEG  A1386 (-4.8A)
None
None
None
None
 1.21A 4hytA-5fipA:
undetectable		 4hytA-5fipA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MS4_A_2C0A501_1
(GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1)		 5fip GH5 CELLULASE
(unidentified) 		4 / 8 SER A 257
SER A 238
ILE A 154
GLU A 294
 None
 1.23A 4ms4A-5fipA:
2.1		 4ms4A-5fipA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA304_1
(TYROSINASE)		 5fip GH5 CELLULASE
(unidentified) 		4 / 5 ASN A 191
HIS A 153
GLU A 188
THR A 293
 None
 1.42A 4p6sA-5fipA:
undetectable		 4p6sA-5fipA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDQ_A_BEZA306_0
(GLYCOSIDE HYDROLASE
FAMILY PROTEIN)		 5fip GH5 CELLULASE
(unidentified) 		3 / 3 ARG A 367
ASP A 107
TRP A 108
 None
 1.22A 4xdqA-5fipA:
undetectable		 4xdqA-5fipA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 5fip GH5 CELLULASE
(unidentified) 		3 / 3 GLU A 316
TRP A 268
ASN A 321
 PEG  A1384 (-4.4A)
PEG  A1387 ( 4.3A)
PEG  A1387 (-3.7A)
 0.83A 5dv4A-5fipA:
undetectable		 5dv4A-5fipA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5fip GH5 CELLULASE
(unidentified) 		5 / 12 ALA A 311
LEU A 308
GLY A 296
SER A 298
PRO A 306
 None
PEG  A1386 (-3.8A)
None
None
PEG  A1386 (-4.8A)
 1.30A 5jglA-5fipA:
undetectable		 5jglA-5fipA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5fip GH5 CELLULASE
(unidentified) 		5 / 12 ALA A 311
LEU A 308
GLY A 296
SER A 298
PRO A 306
 None
PEG  A1386 (-3.8A)
None
None
PEG  A1386 (-4.8A)
 1.34A 5jglB-5fipA:
undetectable		 5jglB-5fipA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 5fip GH5 CELLULASE
(unidentified) 		4 / 6 GLY A 296
THR A 297
SER A 298
ASN A 327
 None
 0.84A 5k4pA-5fipA:
undetectable		 5k4pA-5fipA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5fip GH5 CELLULASE
(unidentified) 		4 / 6 SER A 266
TRP A 314
PHE A 317
GLU A 313
 IPA  A1395 (-4.8A)
None
PEG  A1387 (-4.7A)
None
 1.50A 5uo8A-5fipA:
undetectable
5uo8B-5fipA:
undetectable		 5uo8A-5fipA:
23.44
5uo8B-5fipA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 5fip GH5 CELLULASE
(unidentified) 		3 / 3 THR A 293
GLU A 188
HIS A 153
 None
 0.90A 5xiqB-5fipA:
undetectable		 5xiqB-5fipA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 5fip GH5 CELLULASE
(unidentified) 		3 / 3 THR A 293
GLU A 188
HIS A 153
 None
 0.92A 5xiqD-5fipA:
undetectable		 5xiqD-5fipA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 5fip GH5 CELLULASE
(unidentified) 		5 / 12 ARG A 114
GLU A 188
TYR A 261
ASN A 191
HIS A 153
 None
 1.46A 6b1eB-5fipA:
undetectable		 6b1eB-5fipA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_B_SAMB301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 5fip GH5 CELLULASE
(unidentified) 		5 / 12 ILE A 231
THR A 293
ILE A 138
VAL A 134
ILE A 185
 None
 1.02A 6emuB-5fipA:
undetectable		 6emuB-5fipA:
20.12