SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fje'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_A_IPHA101_0
(INSULIN)		 5fje COPPER STORAGE
PROTEIN 1
(Methylosinus
trichosporium) 		5 / 10 CYH A 110
LEU A  58
CYH A 117
ALA A  61
LEU A  19
 CU1  A1127 ( 2.1A)
CU1  A1127 ( 4.2A)
CU1  A1123 ( 2.1A)
None
CU1  A1123 (-4.9A)
 1.19A 4p65A-5fjeA:
undetectable
4p65B-5fjeA:
undetectable
4p65F-5fjeA:
undetectable
4p65H-5fjeA:
undetectable		 4p65A-5fjeA:
8.33
4p65B-5fjeA:
14.63
4p65F-5fjeA:
14.63
4p65H-5fjeA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 5fje COPPER STORAGE
PROTEIN 1
(Methylosinus
trichosporium) 		5 / 12 VAL A  29
ASP A  32
ASP A  21
HIS A  25
ALA A 109
 None
None
None
None
CU1  A1127 ( 4.2A)
 1.39A 5hnzB-5fjeA:
undetectable		 5hnzB-5fjeA:
16.31