SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fji'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_D_ESTD352_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		4 / 6 SER A 551
VAL A 552
GLY A 553
GLU A 198
 None
 0.83A 1fduD-5fjiA:
3.2		 1fduD-5fjiA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		3 / 3 GLN A  53
TYR A 343
ARG A 349
 None
EDO  A1871 ( 4.3A)
None
 0.94A 1gtbA-5fjiA:
undetectable		 1gtbA-5fjiA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_2
(HIV-II PROTEASE)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 9 ALA A 128
ILE A 393
GLY A  97
ILE A  98
PRO A 458
 None
 0.94A 1hshB-5fjiA:
undetectable		 1hshB-5fjiA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KB9_A_PCFA514_0
(CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		4 / 8 SER A 849
ILE A 646
VAL A 402
SER A 551
 None
 1.16A 1kb9A-5fjiA:
undetectable
1kb9C-5fjiA:
undetectable
1kb9D-5fjiA:
undetectable
1kb9E-5fjiA:
undetectable		 1kb9A-5fjiA:
20.17
1kb9C-5fjiA:
19.11
1kb9D-5fjiA:
14.56
1kb9E-5fjiA:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		3 / 3 PRO A  32
ASP A 333
ASP A  35
 None
None
EDO  A1874 ( 4.5A)
 0.64A 1sqfA-5fjiA:
undetectable		 1sqfA-5fjiA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 12 LEU A 583
THR A 401
THR A 462
ASP A 425
GLY A 573
 None
 1.44A 1v8bA-5fjiA:
undetectable		 1v8bA-5fjiA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YNN_C_RFPC1120_1
(DNA-DIRECTED RNA
POLYMERASE BETA
CHAIN)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 12 ASP A 281
ARG A 201
HIS A 191
ARG A 157
LEU A  96
 EDO  A1881 (-3.9A)
None
None
None
None
 1.29A 1ynnC-5fjiA:
0.0		 1ynnC-5fjiA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 12 GLY A 346
GLY A 184
ARG A  46
ILE A  85
MET A 339
 EDO  A1876 (-3.6A)
EDO  A1880 ( 4.3A)
EDO  A1876 (-3.9A)
None
None
 1.13A 2b25B-5fjiA:
undetectable		 2b25B-5fjiA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		4 / 6 HIS A 389
PHE A 107
GLY A 126
LYS A 127
 None
None
None
EDO  A1877 (-2.7A)
 1.48A 2i30A-5fjiA:
undetectable		 2i30A-5fjiA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 12 ALA A 235
ASP A 236
LEU A 272
LEU A 267
LEU A 761
 None
 1.01A 2jfaB-5fjiA:
undetectable		 2jfaB-5fjiA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		4 / 6 ARG A 337
GLY A 276
PHE A 274
PRO A 755
 None
 1.02A 2m2oB-5fjiA:
undetectable		 2m2oB-5fjiA:
3.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 9 THR A  55
TYR A 699
ALA A  57
LEU A  56
THR A 318
 None
None
NAG  A1001 ( 4.0A)
None
None
 1.26A 2npnA-5fjiA:
undetectable		 2npnA-5fjiA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_2
(PROTEASE)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 12 ARG A 347
GLY A 143
GLY A  97
ILE A  98
ILE A 180
 None
 0.95A 2o4sB-5fjiA:
undetectable		 2o4sB-5fjiA:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		4 / 6 ARG A 636
ASP A 824
ASN A 821
ASP A 764
 None
 1.21A 2okcA-5fjiA:
undetectable		 2okcA-5fjiA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		4 / 6 THR A 482
THR A 445
ASP A 442
ASP A 516
 None
None
None
NAG  A1501 (-3.6A)
 1.29A 2okcA-5fjiA:
undetectable		 2okcA-5fjiA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 12 GLY A 314
GLY A  67
SER A 311
VAL A 371
ILE A 706
 EDO  A1870 ( 3.7A)
None
EDO  A1870 (-4.9A)
None
NAG  A1002 ( 4.6A)
 1.00A 2wa2A-5fjiA:
undetectable		 2wa2A-5fjiA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		4 / 7 TYR A 249
ARG A 201
GLU A 510
SER A 452
 None
None
EDO  A1872 ( 4.9A)
EDO  A1881 ( 3.8A)
 1.21A 2zt7A-5fjiA:
2.8		 2zt7A-5fjiA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 10 GLU A  58
ILE A  85
GLY A  84
ILE A  50
MET A 339
 None
None
EDO  A1871 ( 4.6A)
None
None
 1.35A 3adsA-5fjiA:
undetectable		 3adsA-5fjiA:
16.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 12 ILE A 338
LEU A 142
LEU A 141
ILE A 186
MET A 279
 None
EDO  A1881 ( 4.0A)
None
None
None
 1.26A 3adsB-5fjiA:
undetectable		 3adsB-5fjiA:
16.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		3 / 3 THR A 656
SER A 594
LYS A 596
 EDO  A1875 ( 4.7A)
None
None
 1.11A 3aocC-5fjiA:
undetectable		 3aocC-5fjiA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_1
(CYTOCHROME P450 2R1)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 12 VAL A 336
ALA A 335
ALA A 328
MET A 339
THR A 340
 None
 1.09A 3czhA-5fjiA:
undetectable		 3czhA-5fjiA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_B_V2HB602_0
(CYTOCHROME P450 2R1)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 12 VAL A 336
ALA A 335
ALA A 328
MET A 339
THR A 340
 None
 1.08A 3dl9B-5fjiA:
undetectable		 3dl9B-5fjiA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		3 / 3 ARG A 522
ILE A 549
TRP A 571
 None
 1.11A 3e7iB-5fjiA:
undetectable		 3e7iB-5fjiA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		4 / 4 GLY A 756
VAL A 238
GLY A 170
THR A 169
 None
 0.94A 3ib2A-5fjiA:
undetectable		 3ib2A-5fjiA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID6_C_SAMC301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 12 GLY A 126
ALA A 122
ALA A 183
ILE A 180
GLN A 181
 None
 1.00A 3id6C-5fjiA:
undetectable		 3id6C-5fjiA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 12 ASN A 250
GLY A 156
ARG A 522
VAL A 552
ILE A 158
 None
 1.44A 3jb2A-5fjiA:
2.6		 3jb2A-5fjiA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 12 GLY A 485
GLY A 423
ALA A 491
ALA A 494
ASP A 492
 MAN  A1506 (-3.3A)
None
None
None
EDO  A1864 ( 4.8A)
 1.07A 3keeA-5fjiA:
undetectable		 3keeA-5fjiA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 12 GLY A 485
GLY A 423
ALA A 491
ALA A 494
ASP A 492
 MAN  A1506 (-3.3A)
None
None
None
EDO  A1864 ( 4.8A)
 1.10A 3keeD-5fjiA:
undetectable		 3keeD-5fjiA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		3 / 3 LEU A 404
TRP A 571
GLY A 553
 None
 0.80A 3l35A-5fjiA:
undetectable
3l35H-5fjiA:
undetectable		 3l35A-5fjiA:
3.83
3l35H-5fjiA:
1.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		3 / 3 LEU A 404
TRP A 571
GLY A 553
 None
 0.81A 3l35B-5fjiA:
undetectable
3l35K-5fjiA:
undetectable		 3l35B-5fjiA:
3.83
3l35K-5fjiA:
1.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 9 VAL A 504
ILE A 535
ALA A 568
THR A 567
VAL A 538
 None
 1.01A 3me6C-5fjiA:
undetectable		 3me6C-5fjiA:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBR_A_ASDA129_1
(STEROID
DELTA-ISOMERASE)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 12 SER A 452
VAL A  74
PHE A 100
PRO A 301
PHE A 306
 EDO  A1881 ( 3.8A)
None
EDO  A1873 ( 4.0A)
None
EDO  A1882 (-4.0A)
 1.38A 3nbrA-5fjiA:
undetectable		 3nbrA-5fjiA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		3 / 3 HIS A 637
ARG A 641
GLU A 643
 None
 1.03A 3qf1A-5fjiA:
undetectable		 3qf1A-5fjiA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_3
(NS3 PROTEASE, NS4A
PROTEIN)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		4 / 5 SER A  79
PRO A 712
TYR A 711
VAL A  60
 NAG  A1001 (-2.7A)
None
NAG  A1002 ( 4.3A)
None
 1.33A 3sufC-5fjiA:
undetectable		 3sufC-5fjiA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 12 HIS A 550
VAL A 502
GLY A 576
SER A 579
ALA A 398
 None
 0.99A 3sufD-5fjiA:
undetectable		 3sufD-5fjiA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		4 / 7 HIS A 550
LEU A 583
GLY A 576
PHE A 457
 None
 0.91A 3tehB-5fjiA:
undetectable		 3tehB-5fjiA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_1
(GLYCINE
N-METHYLTRANSFERASE)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		3 / 3 LEU A 231
HIS A 227
MET A 226
 None
 0.90A 3thrD-5fjiA:
2.5		 3thrD-5fjiA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 9 ARG A 822
LEU A 668
ASP A 764
LEU A 820
ASN A 821
 None
 1.46A 3wdmA-5fjiA:
undetectable		 3wdmA-5fjiA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		4 / 5 GLY A  65
ILE A 710
VAL A  60
SER A 311
 None
EDO  A1870 (-4.1A)
None
EDO  A1870 (-4.9A)
 1.26A 4d33B-5fjiA:
undetectable		 4d33B-5fjiA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DCM_A_SAMA401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE G)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 11 ALA A 506
GLY A 573
ILE A 549
ASN A 581
ASN A 505
 None
None
None
EDO  A1867 (-4.4A)
None
 1.14A 4dcmA-5fjiA:
undetectable		 4dcmA-5fjiA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		4 / 7 VAL A 171
VAL A 167
LEU A 800
VAL A 788
 None
 1.12A 4e1gB-5fjiA:
undetectable		 4e1gB-5fjiA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		3 / 3 ARG A 741
TRP A 329
GLY A 743
 IMD  A1885 (-3.5A)
None
None
 0.81A 4e7cA-5fjiA:
undetectable		 4e7cA-5fjiA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_B_BEZB1000_0
(BENZOATE-COENZYME A
LIGASE)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 9 ALA A 595
ALA A 572
GLY A 573
ILE A 549
ILE A 570
 None
 1.13A 4eatB-5fjiA:
2.5		 4eatB-5fjiA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		4 / 5 GLY A 314
VAL A  60
PRO A 712
TYR A 699
 EDO  A1870 ( 3.7A)
None
None
None
 0.87A 4grkA-5fjiA:
undetectable		 4grkA-5fjiA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		4 / 5 ASP A 381
ASN A 355
ILE A 352
VAL A 385
 None
 1.35A 4hytA-5fjiA:
4.9		 4hytA-5fjiA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		4 / 8 MET A 448
ALA A 449
VAL A  74
PHE A 100
 None
None
None
EDO  A1873 ( 4.0A)
 0.86A 4ltwA-5fjiA:
undetectable		 4ltwA-5fjiA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_2
(ADENOSINE KINASE)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		4 / 5 ASN A 250
SER A 218
LEU A 613
ASN A 617
 None
 0.98A 4n09C-5fjiA:
undetectable		 4n09C-5fjiA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_E_PARE500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 12 SER A 358
PHE A 356
SER A 369
ASP A 307
GLY A  75
 None
 1.30A 4qb9E-5fjiA:
undetectable		 4qb9E-5fjiA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W9N_C_CCSC1548_0
(ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		3 / 3 ALA A 826
TRP A 835
VAL A 836
 None
 0.40A 4w9nC-5fjiA:
4.1		 4w9nC-5fjiA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 12 ALA A 235
ASP A 236
LEU A 272
LEU A 267
LEU A 761
 None
 0.96A 4xi3B-5fjiA:
undetectable		 4xi3B-5fjiA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB201_0
(HYDROXYNITRILE LYASE)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 11 VAL A 278
VAL A 245
ILE A 252
ILE A 193
LEU A 268
 None
None
NAG  A1101 (-4.4A)
None
None
 1.04A 5e4dB-5fjiA:
undetectable		 5e4dB-5fjiA:
15.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		4 / 6 TYR A 249
GLY A 511
GLU A 510
ASP A 438
 None
None
EDO  A1872 ( 4.9A)
EDO  A1872 ( 4.8A)
 1.27A 5emlA-5fjiA:
2.5		 5emlA-5fjiA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FQD_E_LVYE1438_1
(PROTEIN CEREBLON
CASEIN KINASE I
ISOFORM ALPHA)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 12 SER A 369
TRP A 359
TRP A  68
ILE A 710
GLY A  67
 None
None
None
EDO  A1870 (-4.1A)
None
 1.34A 5fqdE-5fjiA:
undetectable
5fqdF-5fjiA:
undetectable		 5fqdE-5fjiA:
18.15
5fqdF-5fjiA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 11 THR A 678
THR A 760
GLY A 752
GLY A 757
ALA A 754
 None
 1.01A 5lf3K-5fjiA:
undetectable
5lf3L-5fjiA:
undetectable		 5lf3K-5fjiA:
13.77
5lf3L-5fjiA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M6G_A_SORA711_0
(BETA-GLUCOSIDASE)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		6 / 12 ASP A  93
ARG A 157
LYS A 190
HIS A 191
MET A 246
GLU A 510
 EDO  A1881 (-2.9A)
None
EDO  A1881 (-3.1A)
None
EDO  A1881 (-3.8A)
EDO  A1872 ( 4.9A)
 0.43A 5m6gA-5fjiA:
30.1		 5m6gA-5fjiA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		4 / 5 LEU A 501
VAL A 419
GLU A 416
LEU A 412
 None
 1.12A 5xooB-5fjiA:
undetectable		 5xooB-5fjiA:
6.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		4 / 5 LEU A 501
VAL A 499
GLU A 416
LEU A 412
 None
 1.11A 5xooB-5fjiA:
undetectable		 5xooB-5fjiA:
6.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_A_P2EA1201_0
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 12 VAL A 471
TYR A 588
LEU A 501
SER A 497
GLN A 496
 None
EDO  A1865 (-4.2A)
None
None
EDO  A1864 (-3.0A)
 1.35A 6ak3A-5fjiA:
undetectable		 6ak3A-5fjiA:
7.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		4 / 5 PRO A 860
VAL A 766
GLY A 847
VAL A 788
 None
 1.03A 6ak3B-5fjiA:
undetectable		 6ak3B-5fjiA:
7.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		4 / 6 SER A 219
GLN A 197
GLU A 629
THR A 225
 None
 1.43A 6djzA-5fjiA:
undetectable		 6djzA-5fjiA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 9 ASP A 625
SER A 219
TYR A 152
GLY A 509
ASN A 195
 None
 1.36A 6giqA-5fjiA:
0.7
6giqE-5fjiA:
undetectable
6giqI-5fjiA:
undetectable		 6giqA-5fjiA:
22.52
6giqE-5fjiA:
15.11
6giqI-5fjiA:
6.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NQA_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 10 GLY A 509
GLY A 156
VAL A 552
GLU A 198
ASN A 518
 None
None
None
None
NAG  A1501 (-3.4A)
 1.20A 6nqaK-5fjiA:
undetectable		 6nqaK-5fjiA:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NQA_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 5fji BETA-GLUCOSIDASE
(Aspergillus
fumigatus) 		5 / 10 GLY A 520
GLY A 156
VAL A 552
GLU A 198
ASN A 518
 None
None
None
None
NAG  A1501 (-3.4A)
 1.49A 6nqaK-5fjiA:
undetectable		 6nqaK-5fjiA:
19.98